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The map label for this gene is ruvB [H]

Identifier: 209550797

GI number: 209550797

Start: 3308122

End: 3309162

Strand: Direct

Name: ruvB [H]

Synonym: Rleg2_3221

Alternate gene names: 209550797

Gene position: 3308122-3309162 (Clockwise)

Preceding gene: 209550796

Following gene: 209550798

Centisome position: 72.9

GC content: 63.78

Gene sequence:

>1041_bases
ATGAGCGAACCCGCCCGCCTGATATCGCCGGAAAAGCGGGGCGAAGATCTCGACATCACCTTGCGCCCGCAATCGCTGGA
CGAATTCACCGGCCAGGCGGAAGCGCGCGCCAATCTCAAGGTCTTCATCGAGGCGGCGAAGAATCGCGGCGAGGCGCTGG
ACCATGTGCTCTTCGTCGGCCCGCCCGGCCTCGGCAAGACGACGCTGGCGCAGATCATGGCGAAGGAACTCGGCGTCAAT
TTCCGCTCGACGTCAGGTCCCGTGATTGCCAAGGCCGGCGATCTCGCCGCGCTGCTCACCAATCTCGAGGAGCGCGACGT
GCTCTTCATCGACGAGATCCATCGCCTCAACCCGGCTGTCGAGGAAATTCTCTATCCGGCCATGGAAGATTTCCAGCTCG
ACCTGATCATCGGCGAAGGCCCCGCCGCCCGCTCGGTGAAAATCGATCTGTCGAAATTCACCCTGGTGGCGGCCACCACC
CGCCTCGGCCTGCTGACGACGCCGCTGCGCGACCGTTTCGGCATCCCGGTGCGCCTGAGCTTTTATACCGTCGAGGAGCT
GGAATTGATCGTTCGCCGCGGCGCGCGGCTGATGAACCTACCGATAACCGAAGAGGGCGCCCGCGAAATAGCAAGACGCG
CCCGCGGCACACCGCGCATCGCCGGCCGTCTGCTGCGGCGCGTGCGCGATTTCGCCGAGGTGGCAAGGGCCGAGGCGGTG
ACGCGTGAGATCGCCGACGAGGCGCTGACCCGCTTGCTGGTCGACAATGTCGGCTTCGACCAGCTCGACAAACGTTACCT
CAACATGATCGCCGTCAATTTCGGCGGCGGCCCGGTCGGCATCGAAACCATCGCCGCCGGCCTTTCCGAGCCGCGTGACG
CGATCGAGGACATCATCGAGCCTTATATGATCCAGCAGGGTTTCATTCAGCGCACGCCACGCGGCCGTGTTCTGACCGCA
ATCGCGTGGAAACATCTCGGAATGCAACCGCCCAAGGAAATGGAGGCTGCGCAGTTCCGGCTGTTCCAGGAGGACAACTG
A

Upstream 100 bases:

>100_bases
AAGGAACTGGCACGGTGAAGGCCGGAAAACCGATGATTGGATGTCGAGGCGGCCGGTTTTTGGTGTATTGCTGTGACAGG
TTTCAAAACGGAATGAGAGC

Downstream 100 bases:

>100_bases
GTGATCACCCGCCGCGGATTCTTCAAGGTTCTTGGCGGCGGCATTGCAGGCGTCATGTCGCTTGGTGGTTACGCCTTCGC
TTATGAACCGCTGGCGCGGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVN
FRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATT
RLGLLTTPLRDRFGIPVRLSFYTVEELELIVRRGARLMNLPITEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
TREIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIEPYMIQQGFIQRTPRGRVLTA
IAWKHLGMQPPKEMEAAQFRLFQEDN

Sequences:

>Translated_346_residues
MSEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVN
FRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATT
RLGLLTTPLRDRFGIPVRLSFYTVEELELIVRRGARLMNLPITEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
TREIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIEPYMIQQGFIQRTPRGRVLTA
IAWKHLGMQPPKEMEAAQFRLFQEDN
>Mature_345_residues
SEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATTR
LGLLTTPLRDRFGIPVRLSFYTVEELELIVRRGARLMNLPITEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAVT
REIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIEPYMIQQGFIQRTPRGRVLTAI
AWKHLGMQPPKEMEAAQFRLFQEDN

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=61.377245508982, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1787119, Length=268, Percent_Identity=25.7462686567164, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38414; Mature: 38283

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVG
CCCCCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHCCCHHEEEEEHHCCCHHHHEEEEEC
PPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATTRLGLLTTPLRDRFGIPVRLS
HHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHEECCHHHHCCCCEEEE
FYTVEELELIVRRGARLMNLPITEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
EEEHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TREIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHH
PYMIQQGFIQRTPRGRVLTAIAWKHLGMQPPKEMEAAQFRLFQEDN
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVG
CCCCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHCCCHHEEEEEHHCCCHHHHEEEEEC
PPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATTRLGLLTTPLRDRFGIPVRLS
HHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHEECCHHHHCCCCEEEE
FYTVEELELIVRRGARLMNLPITEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
EEEHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TREIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHH
PYMIQQGFIQRTPRGRVLTAIAWKHLGMQPPKEMEAAQFRLFQEDN
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA