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The map label for this gene is ruvA [H]

Identifier: 209550796

GI number: 209550796

Start: 3307425

End: 3308039

Strand: Direct

Name: ruvA [H]

Synonym: Rleg2_3220

Alternate gene names: 209550796

Gene position: 3307425-3308039 (Clockwise)

Preceding gene: 209550795

Following gene: 209550797

Centisome position: 72.88

GC content: 65.53

Gene sequence:

>615_bases
ATGATCGGCAAGCTGAAAGGCACCATAGACGAGATCGGCGAAGACTATGTGCTCGTCGATGTGCACGGCGTCTGCTACGT
CGCCCACTGCTCGGCCCGCACCCTGTCCAAGCTCGGCTCGGCCGACGAGGCCTGCGTGCTGTTCATCGAGACCTATGTGC
GCGAGGACCAGTTGAAGCTGTTCGGCTTTATGACCGCCTTGGAGCGGGAATGGTTCAATCTGCTGCAGAGTGTCCAGGGC
GTCGGCGCCAAGGTGGCGCTCGCCGTGCTCTCGACCCTGACGCCGGGCGAACTCGCCAATGCGATCGCCCTGCAGGACCG
CGCCGCTGTCTCCCGCGCGCCGGGCGTCGGCCCGAAGGTGGCCATGCGTCTCGTCACCGAACTCAAGAACCGGGCGCCGG
CCTTTGCCGGGGAAGCGATCAATATCGCCCTCAAGCAGGAGCTCGGCGAAGGTGTCGCGGCCGCCCCCGTGGCCGATGCG
GTTTCAGCGCTGACCAACCTCGGCTACAGCAGAGACCAGGCCGCCAACGCGGTTGCCGCAGCAATGAAGACGGCCGGCGA
CGACGCCGATAGCGCCAAGCTGATCAGGCTGGGATTGAAGGAACTGGCACGGTGA

Upstream 100 bases:

>100_bases
GGCTACAAGATTTTGACCCGCGACCCCCGCGGATACCGATCTTATTTCCCCTCCGTTGAACTTATCACGCCTGAAACCCA
CCCTTGAGAGACCGCGCCCC

Downstream 100 bases:

>100_bases
AGGCCGGAAAACCGATGATTGGATGTCGAGGCGGCCGGTTTTTGGTGTATTGCTGTGACAGGTTTCAAAACGGAATGAGA
GCATGAGCGAACCCGCCCGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSADEACVLFIETYVREDQLKLFGFMTALEREWFNLLQSVQG
VGAKVALAVLSTLTPGELANAIALQDRAAVSRAPGVGPKVAMRLVTELKNRAPAFAGEAINIALKQELGEGVAAAPVADA
VSALTNLGYSRDQAANAVAAAMKTAGDDADSAKLIRLGLKELAR

Sequences:

>Translated_204_residues
MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSADEACVLFIETYVREDQLKLFGFMTALEREWFNLLQSVQG
VGAKVALAVLSTLTPGELANAIALQDRAAVSRAPGVGPKVAMRLVTELKNRAPAFAGEAINIALKQELGEGVAAAPVADA
VSALTNLGYSRDQAANAVAAAMKTAGDDADSAKLIRLGLKELAR
>Mature_204_residues
MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSADEACVLFIETYVREDQLKLFGFMTALEREWFNLLQSVQG
VGAKVALAVLSTLTPGELANAIALQDRAAVSRAPGVGPKVAMRLVTELKNRAPAFAGEAINIALKQELGEGVAAAPVADA
VSALTNLGYSRDQAANAVAAAMKTAGDDADSAKLIRLGLKELAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=36.0975609756098, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21397; Mature: 21397

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSADEACVLFIETYVREDQLKL
CCCCCCCCHHHCCCCEEEEEECCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FGFMTALEREWFNLLQSVQGVGAKVALAVLSTLTPGELANAIALQDRAAVSRAPGVGPKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHH
AMRLVTELKNRAPAFAGEAINIALKQELGEGVAAAPVADAVSALTNLGYSRDQAANAVAA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
AMKTAGDDADSAKLIRLGLKELAR
HHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSADEACVLFIETYVREDQLKL
CCCCCCCCHHHCCCCEEEEEECCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FGFMTALEREWFNLLQSVQGVGAKVALAVLSTLTPGELANAIALQDRAAVSRAPGVGPKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHH
AMRLVTELKNRAPAFAGEAINIALKQELGEGVAAAPVADAVSALTNLGYSRDQAANAVAA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
AMKTAGDDADSAKLIRLGLKELAR
HHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA