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The map label for this gene is mraY [H]

Identifier: 209550177

GI number: 209550177

Start: 2637490

End: 2638590

Strand: Reverse

Name: mraY [H]

Synonym: Rleg2_2597

Alternate gene names: 209550177

Gene position: 2638590-2637490 (Counterclockwise)

Preceding gene: 209550178

Following gene: 209550176

Centisome position: 58.15

GC content: 60.76

Gene sequence:

>1101_bases
ATGCTGATCTGGCTTGTCGAACTGTCGGAATATTTCAAATTTCTGAACCTGTTCAGATATATTACCTTCCGTACAGGCGC
TGCTCTCTTCACCTCAGCCCTGATCGTCTTCCTGTTCGGACCGACGATCATCAATTCGCTGCGTATCCGGCAGGGCAAGG
GCCAGCCGATCCGCGCCGATGGGCCGCAGACCCATTTCAAGAAGGCCGGCACGCCGACCATGGGCGGGCTGATGATCCTT
GCCGGCATCGTCGGCGCGTCGCTGCTCTGGGCCGATCTTTCCAACGTCTATGTCGTCGCCACGCTGCTGGTGACGCTCGG
CTTCGGCGCGATCGGCTTCTATGACGATTATCTCAAGGTCACCAAGCAGAGCCATATGGGCTTTTCCGGCAAGGCGCGTC
TCGGCATCGAATTCGTCATCGCCGGCATCGCCGTCTATTTCATGATGCGCACCGCTCTTGCCTCGGGCGTTGCCGGCTCG
ACCTTCGGCTCGTCGATCGCCTTTCCCTTCTTCAAGGACTTCATGATCAATATCGGCATCATGTTCGTCGTCTTCGGCGG
CTTCGTGATCGTCGGCGCCGGAAATGCCGTCAACCTGACCGACGGCCTTGACGGGCTTGCTATCGTGCCTGTCATGATCG
CCGCCGCCTCCTTCGGCGTCATTGCCTATCTCGCCGGCAACGTGGTGTTTGCGAACTACCTGCAGATCAATTTCGTGCCC
GGCACCGGCGAGCTCGCCGTCGTTCTCGGCGCCGTTATCGGCGCCGGCCTCGGCTTTCTCTGGTTCAACGCGCCGCCGGC
CGCCATCTTCATGGGCGATACCGGCTCGCTCGCACTCGGCGGTACGATCGGCACTGTTGCCGTCGCCACCAAGCACGAGA
TCGTCATGGCGATCATCGGCGGCCTCTTCGTCATGGAGACGCTCTCGGTCATCATCCAGGTCGGCTTCTTCAAGATGACC
GGCCGGCGCGTCTTCCTGATGGCGCCGATCCATCACCACTTCGAGAAGAAGGGCTGGACCGAAAGCCAGGTGGTGATCCG
CTTCTGGATCATCGCCGTCGGCCTTGCCATGCTCGGCCTCTCGACGCTGAAGCTGCGGTGA

Upstream 100 bases:

>100_bases
GGCATCGGTTTCGGCAAGATCGTTGCCGCGCTCCTTGACAAGTTCCCGCCATTTTCCGACACGCAACGCGAATTTTGATC
GGGTAAATAAGGGGCCCTGA

Downstream 100 bases:

>100_bases
GGCGGCGATGATCCCGGTCACGACGCTCAAGGACAGGAAGGTCGCGCTCTTCGGGCTCGGCGGCTCGGGCCTTGCCACCG
CCCGGGCGCTGGTTTCGGGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLIWLVELSEYFKFLNLFRYITFRTGAALFTSALIVFLFGPTIINSLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGIVGASLLWADLSNVYVVATLLVTLGFGAIGFYDDYLKVTKQSHMGFSGKARLGIEFVIAGIAVYFMMRTALASGVAGS
TFGSSIAFPFFKDFMINIGIMFVVFGGFVIVGAGNAVNLTDGLDGLAIVPVMIAAASFGVIAYLAGNVVFANYLQINFVP
GTGELAVVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGTIGTVAVATKHEIVMAIIGGLFVMETLSVIIQVGFFKMT
GRRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVGLAMLGLSTLKLR

Sequences:

>Translated_366_residues
MLIWLVELSEYFKFLNLFRYITFRTGAALFTSALIVFLFGPTIINSLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGIVGASLLWADLSNVYVVATLLVTLGFGAIGFYDDYLKVTKQSHMGFSGKARLGIEFVIAGIAVYFMMRTALASGVAGS
TFGSSIAFPFFKDFMINIGIMFVVFGGFVIVGAGNAVNLTDGLDGLAIVPVMIAAASFGVIAYLAGNVVFANYLQINFVP
GTGELAVVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGTIGTVAVATKHEIVMAIIGGLFVMETLSVIIQVGFFKMT
GRRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVGLAMLGLSTLKLR
>Mature_366_residues
MLIWLVELSEYFKFLNLFRYITFRTGAALFTSALIVFLFGPTIINSLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGIVGASLLWADLSNVYVVATLLVTLGFGAIGFYDDYLKVTKQSHMGFSGKARLGIEFVIAGIAVYFMMRTALASGVAGS
TFGSSIAFPFFKDFMINIGIMFVVFGGFVIVGAGNAVNLTDGLDGLAIVPVMIAAASFGVIAYLAGNVVFANYLQINFVP
GTGELAVVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGTIGTVAVATKHEIVMAIIGGLFVMETLSVIIQVGFFKMT
GRRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVGLAMLGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=368, Percent_Identity=50, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39051; Mature: 39051

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIWLVELSEYFKFLNLFRYITFRTGAALFTSALIVFLFGPTIINSLRIRQGKGQPIRAD
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
GPQTHFKKAGTPTMGGLMILAGIVGASLLWADLSNVYVVATLLVTLGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TKQSHMGFSGKARLGIEFVIAGIAVYFMMRTALASGVAGSTFGSSIAFPFFKDFMINIGI
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
MFVVFGGFVIVGAGNAVNLTDGLDGLAIVPVMIAAASFGVIAYLAGNVVFANYLQINFVP
HHHHHCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEC
GTGELAVVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGTIGTVAVATKHEIVMAIIG
CCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCEEECCCHHEEEEHHHHHHHHHHHH
GLFVMETLSVIIQVGFFKMTGRRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVGLAMLGL
HHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCH
STLKLR
HHHCCC
>Mature Secondary Structure
MLIWLVELSEYFKFLNLFRYITFRTGAALFTSALIVFLFGPTIINSLRIRQGKGQPIRAD
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
GPQTHFKKAGTPTMGGLMILAGIVGASLLWADLSNVYVVATLLVTLGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TKQSHMGFSGKARLGIEFVIAGIAVYFMMRTALASGVAGSTFGSSIAFPFFKDFMINIGI
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
MFVVFGGFVIVGAGNAVNLTDGLDGLAIVPVMIAAASFGVIAYLAGNVVFANYLQINFVP
HHHHHCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEC
GTGELAVVLGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGTIGTVAVATKHEIVMAIIG
CCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCEEECCCHHEEEEHHHHHHHHHHHH
GLFVMETLSVIIQVGFFKMTGRRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVGLAMLGL
HHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCH
STLKLR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA