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The map label for this gene is hflK [H]

Identifier: 209550123

GI number: 209550123

Start: 2573101

End: 2574189

Strand: Reverse

Name: hflK [H]

Synonym: Rleg2_2541

Alternate gene names: 209550123

Gene position: 2574189-2573101 (Counterclockwise)

Preceding gene: 209550124

Following gene: 209550122

Centisome position: 56.73

GC content: 62.63

Gene sequence:

>1089_bases
ATGCCCTGGAGCAATCAGAATGGCGGCGGCGGCCCTTGGGGCGGCGGCGGCGGTAATAATAATCAGGGACCATGGGGCCA
GGGGCCGAACCGCCCGCGGGGCGGTGGCAGCGGCAAGGGCGGACCGCCCGATCTGGAAGATATCATCCGGCGCGGCCAGG
ACCAGCTGCGCAACATCGTTCCCGGCGGTTTCAACGGCGGCGTGGCGGTGATCGTCGCGGCGGTCGTCGCCATTTTCTGG
CTGATCCAGTGCGTCTACGTGGTGCAGCCGGACGAACGCGGCGTCGAGCTGCGGTTCGGCAAGCCGAAGGACGAGATCTC
GATGCCCGGCCTGCATTTCCATCTCTGGCCGCTGGAATCCGTTGAGACCGTCAAGGTGACCGTGCAACAGCTGAATATCG
GAGCGACCTCTGCGTCGTCTTCAAACGGGCTGATGCTGTCGAGCGACAAGAGCGTCATCAATGTACAGTTCGCCGTCTTC
TACACGGTCAGCGATCCGAAGGCCTATCTCTTCAACGTCGAAAATCCGGCAGAGACCCTGCAGCAGGTTTCCGACAGCGC
CATGCGCGAAATCGTCGGGCGTCGTCCGGCGCAGGACGCCTTCCGCAGCAATCGCCAGCCGATCGAAGTGGATGTGCTCA
ATATCGTACAGGATACGATGAACCGTTACGGCGCCGGCGTGACCGTGACCGGTGTGACGATCCAGAACGTGGCGCCGCCG
CGCGAAGTCGCCGATGCCTTCGAAGAAGTGCAGCGTGCCGGCCGAGACCGCGACAGCACGATCGAAGACGCCAACCGCTA
TACCAACCAGAAGCTCGGTCAGGCGCGAGGCGATGCGGCACGAATCCGTGAAGATGCAGCCGCCTACAAGAACCGTGTCG
TGAAGGAGGCGGAAGGTGAGGCGCAGCGCTTCACCGCAATCAACGACGAATATTCGAAGGCGCCCGAAGTGACCCGCAAG
CGGCTGTTCATCGAAACGATGGAGCAGGTGCTGAAGAACTCGAAGAAGGTCATCATCGACGAGAAGCAGGGCGTGCTGCC
CTATCTGCCGCTCAATGAGCTCGGCAAGCCGGCGCAGCAGGGAGGTTGA

Upstream 100 bases:

>100_bases
GAAAGCCGCTGCGGCGATACTTATAACGGTCCCAACGCATCCGCCGGTCAGCCCCCACGGTTCCGGATGCGTGGAAGACT
TAACGAACAACGAGGTTTTG

Downstream 100 bases:

>100_bases
ACCATGACATCGAACAGACTTCCCATCATTCTCCTCATCCTCGCCATCGTGCTGGTCGGCCTCTATTCGTCGATCTTCGT
GGTGAATGCCCGCGAGCAGG

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPWSNQNGGGGPWGGGGGNNNQGPWGQGPNRPRGGGSGKGGPPDLEDIIRRGQDQLRNIVPGGFNGGVAVIVAAVVAIFW
LIQCVYVVQPDERGVELRFGKPKDEISMPGLHFHLWPLESVETVKVTVQQLNIGATSASSSNGLMLSSDKSVINVQFAVF
YTVSDPKAYLFNVENPAETLQQVSDSAMREIVGRRPAQDAFRSNRQPIEVDVLNIVQDTMNRYGAGVTVTGVTIQNVAPP
REVADAFEEVQRAGRDRDSTIEDANRYTNQKLGQARGDAARIREDAAAYKNRVVKEAEGEAQRFTAINDEYSKAPEVTRK
RLFIETMEQVLKNSKKVIIDEKQGVLPYLPLNELGKPAQQGG

Sequences:

>Translated_362_residues
MPWSNQNGGGGPWGGGGGNNNQGPWGQGPNRPRGGGSGKGGPPDLEDIIRRGQDQLRNIVPGGFNGGVAVIVAAVVAIFW
LIQCVYVVQPDERGVELRFGKPKDEISMPGLHFHLWPLESVETVKVTVQQLNIGATSASSSNGLMLSSDKSVINVQFAVF
YTVSDPKAYLFNVENPAETLQQVSDSAMREIVGRRPAQDAFRSNRQPIEVDVLNIVQDTMNRYGAGVTVTGVTIQNVAPP
REVADAFEEVQRAGRDRDSTIEDANRYTNQKLGQARGDAARIREDAAAYKNRVVKEAEGEAQRFTAINDEYSKAPEVTRK
RLFIETMEQVLKNSKKVIIDEKQGVLPYLPLNELGKPAQQGG
>Mature_361_residues
PWSNQNGGGGPWGGGGGNNNQGPWGQGPNRPRGGGSGKGGPPDLEDIIRRGQDQLRNIVPGGFNGGVAVIVAAVVAIFWL
IQCVYVVQPDERGVELRFGKPKDEISMPGLHFHLWPLESVETVKVTVQQLNIGATSASSSNGLMLSSDKSVINVQFAVFY
TVSDPKAYLFNVENPAETLQQVSDSAMREIVGRRPAQDAFRSNRQPIEVDVLNIVQDTMNRYGAGVTVTGVTIQNVAPPR
EVADAFEEVQRAGRDRDSTIEDANRYTNQKLGQARGDAARIREDAAAYKNRVVKEAEGEAQRFTAINDEYSKAPEVTRKR
LFIETMEQVLKNSKKVIIDEKQGVLPYLPLNELGKPAQQGG

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=364, Percent_Identity=35.7142857142857, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 39424; Mature: 39293

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWSNQNGGGGPWGGGGGNNNQGPWGQGPNRPRGGGSGKGGPPDLEDIIRRGQDQLRNIV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHCC
PGGFNGGVAVIVAAVVAIFWLIQCVYVVQPDERGVELRFGKPKDEISMPGLHFHLWPLES
CCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCHHHCCCCCCEEEECCCCC
VETVKVTVQQLNIGATSASSSNGLMLSSDKSVINVQFAVFYTVSDPKAYLFNVENPAETL
CHHHHEEHHHHCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCEEEEECCCHHHHH
QQVSDSAMREIVGRRPAQDAFRSNRQPIEVDVLNIVQDTMNRYGAGVTVTGVTIQNVAPP
HHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
REVADAFEEVQRAGRDRDSTIEDANRYTNQKLGQARGDAARIREDAAAYKNRVVKEAEGE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
AQRFTAINDEYSKAPEVTRKRLFIETMEQVLKNSKKVIIDEKQGVLPYLPLNELGKPAQQ
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCHHC
GG
CC
>Mature Secondary Structure 
PWSNQNGGGGPWGGGGGNNNQGPWGQGPNRPRGGGSGKGGPPDLEDIIRRGQDQLRNIV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHCC
PGGFNGGVAVIVAAVVAIFWLIQCVYVVQPDERGVELRFGKPKDEISMPGLHFHLWPLES
CCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCHHHCCCCCCEEEECCCCC
VETVKVTVQQLNIGATSASSSNGLMLSSDKSVINVQFAVFYTVSDPKAYLFNVENPAETL
CHHHHEEHHHHCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCEEEEECCCHHHHH
QQVSDSAMREIVGRRPAQDAFRSNRQPIEVDVLNIVQDTMNRYGAGVTVTGVTIQNVAPP
HHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
REVADAFEEVQRAGRDRDSTIEDANRYTNQKLGQARGDAARIREDAAAYKNRVVKEAEGE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
AQRFTAINDEYSKAPEVTRKRLFIETMEQVLKNSKKVIIDEKQGVLPYLPLNELGKPAQQ
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCHHC
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]