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The map label for this gene is rhbB [H]

Identifier: 209549837

GI number: 209549837

Start: 2302589

End: 2304004

Strand: Direct

Name: rhbB [H]

Synonym: Rleg2_2249

Alternate gene names: 209549837

Gene position: 2302589-2304004 (Clockwise)

Preceding gene: 209549836

Following gene: 209549839

Centisome position: 50.74

GC content: 65.61

Gene sequence:

>1416_bases
ATGTCGGCAATTGCATCTCTGTTTCAGGAAGCTGCCCGGCTTGCGGCCGGGTTTCGGCAGGCGACACCCGCCCGCCATAT
GCCCACTCACGACTACGCCACCTCGCTTGCCTGTTTTAACGAACCGCTGCCGACGGTCGGTTCGCAGATGCTTGAGGTCA
TCACGCAGCTCGCAGATGGCGCCGAACCCGGGCTGCATGCGACGACAGGCCCACGCTTCTTCGGTTGGGTCATCGGCGGT
TCCCATCCCGTCGGCGTCGCAGCCGATTTCCTCACCAGCGCCTGGGGCCAGAATGCCGGAAACCATACCGCCGCCCCGGC
CGCAGCCGCCGTCGAGACCGTCGCTGCGAGATGGCTTCTCGATCTCCTGAAGCTGCCGGCTGAAAGCTCAGTCGGTTTCG
TCACGGGCGCGACGGTGGCGAACTTCACCTGCCTTGCCGCCGCCCGCGGCGAGGTGCTGCGCCAGGTCGGCTGGGATGGC
GATGCCCGCGGCCTGTTCAGTGCGCCCGAAATCACCGTGCTGATCGGTGACGATGCTCACACGACGGTATTCTCCGCGCT
GCAATTCCTCGGCCTCGGCCATGATCGCGTGCTGCGCGTGCGCACCGATCCGGTGGGACGGATAGACCCGGCCGCGCTGG
CCGGCGCGCTCGATATGGTCTCCGGTCCCATCATCGCTATTCTGCAGGCGGGGCAGATCAATACCGGCGCTTTCGACGAC
TTCGCCGCGATCATCCCGCTGCTGAAAGCGAAAGGCGCCTGGGTGCATATCGACGGCGCCTTCGGCCTCTGGGCGCAGGC
GTCGGTGAAGACCAGCCATCTCAGCCGCGGCATCGAAGCCGCCGACAGCTGGGCGACCGACGGCCACAAATGGCTGCAGA
CCCCCTATGATTGCGGCTATGCGATCGTCCGCAACGAACTCGCCCATCGCCGCGCCATGACGATCGCCGCAAGCTATCTG
CCGCTCGCCGGCGAAGGCGAACGCGATCCTTCCCACTACGTGCCGGAGCTATCAAGACGGGCGCGCGGCTTTGCCACCTG
GGCGATGCTGAAACATCTCGGCCGTGAAGGCGTGGCCGCCCTCATCGACCAGTGCTGCGCCTCGGCGCGGCTGGCGGCCG
ACCTGCTCGGGCGCGAGCCCGGCATCGCCATTCTGAACGAGGTAACGCTGAACCAGCTCGTCATCCGCTTCGCGGCCGAC
CGTCCGGACGAAGAAGGCGATGCCATGACCAGAAAGACGATCGAAAAGATCCAGGCGGATGGCCTGATCTTCGCCGGCGG
CGCCAAATGGCACGGCCGCGACGTGTTACGCCTCTCCGTCACCAATTTTCAGACGACATCGGATCAGGCGGAACTGGCGG
CGGAGAGCATCATCGCTGCGTACAGGAGCGTCAGCGGCAATTCCCATCAGCGCTAA

Upstream 100 bases:

>100_bases
TTTTGCTGCCAAGACAGCGTCGGCAAGATCGGCTAGACTGCATGCGCCGACAGCTTGCGTCGAGGGCATCCAGGGGACGG
TCGGCGGCAGGGGGATCCGC

Downstream 100 bases:

>100_bases
TGCATGTCGCCCGGAAGTGTGCAGCGGTTCCGGGATAACGACAGGCATCAAAACAAAAGCCGTTGCGTCCTTTGCCAATC
CATAGCCCTGCAAAATCTGG

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSAIASLFQEAARLAAGFRQATPARHMPTHDYATSLACFNEPLPTVGSQMLEVITQLADGAEPGLHATTGPRFFGWVIGG
SHPVGVAADFLTSAWGQNAGNHTAAPAAAAVETVAARWLLDLLKLPAESSVGFVTGATVANFTCLAAARGEVLRQVGWDG
DARGLFSAPEITVLIGDDAHTTVFSALQFLGLGHDRVLRVRTDPVGRIDPAALAGALDMVSGPIIAILQAGQINTGAFDD
FAAIIPLLKAKGAWVHIDGAFGLWAQASVKTSHLSRGIEAADSWATDGHKWLQTPYDCGYAIVRNELAHRRAMTIAASYL
PLAGEGERDPSHYVPELSRRARGFATWAMLKHLGREGVAALIDQCCASARLAADLLGREPGIAILNEVTLNQLVIRFAAD
RPDEEGDAMTRKTIEKIQADGLIFAGGAKWHGRDVLRLSVTNFQTTSDQAELAAESIIAAYRSVSGNSHQR

Sequences:

>Translated_471_residues
MSAIASLFQEAARLAAGFRQATPARHMPTHDYATSLACFNEPLPTVGSQMLEVITQLADGAEPGLHATTGPRFFGWVIGG
SHPVGVAADFLTSAWGQNAGNHTAAPAAAAVETVAARWLLDLLKLPAESSVGFVTGATVANFTCLAAARGEVLRQVGWDG
DARGLFSAPEITVLIGDDAHTTVFSALQFLGLGHDRVLRVRTDPVGRIDPAALAGALDMVSGPIIAILQAGQINTGAFDD
FAAIIPLLKAKGAWVHIDGAFGLWAQASVKTSHLSRGIEAADSWATDGHKWLQTPYDCGYAIVRNELAHRRAMTIAASYL
PLAGEGERDPSHYVPELSRRARGFATWAMLKHLGREGVAALIDQCCASARLAADLLGREPGIAILNEVTLNQLVIRFAAD
RPDEEGDAMTRKTIEKIQADGLIFAGGAKWHGRDVLRLSVTNFQTTSDQAELAAESIIAAYRSVSGNSHQR
>Mature_470_residues
SAIASLFQEAARLAAGFRQATPARHMPTHDYATSLACFNEPLPTVGSQMLEVITQLADGAEPGLHATTGPRFFGWVIGGS
HPVGVAADFLTSAWGQNAGNHTAAPAAAAVETVAARWLLDLLKLPAESSVGFVTGATVANFTCLAAARGEVLRQVGWDGD
ARGLFSAPEITVLIGDDAHTTVFSALQFLGLGHDRVLRVRTDPVGRIDPAALAGALDMVSGPIIAILQAGQINTGAFDDF
AAIIPLLKAKGAWVHIDGAFGLWAQASVKTSHLSRGIEAADSWATDGHKWLQTPYDCGYAIVRNELAHRRAMTIAASYLP
LAGEGERDPSHYVPELSRRARGFATWAMLKHLGREGVAALIDQCCASARLAADLLGREPGIAILNEVTLNQLVIRFAADR
PDEEGDAMTRKTIEKIQADGLIFAGGAKWHGRDVLRLSVTNFQTTSDQAELAAESIIAAYRSVSGNSHQR

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197276620, Length=375, Percent_Identity=24.2666666666667, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4503875, Length=375, Percent_Identity=24.2666666666667, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI194294551, Length=328, Percent_Identity=26.8292682926829, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI58331246, Length=371, Percent_Identity=23.989218328841, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4503281, Length=425, Percent_Identity=24.7058823529412, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI132814448, Length=425, Percent_Identity=24.7058823529412, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI197383062, Length=329, Percent_Identity=25.531914893617, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI92110055, Length=358, Percent_Identity=24.5810055865922, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534817, Length=441, Percent_Identity=25.8503401360544, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17534819, Length=441, Percent_Identity=25.8503401360544, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71993058, Length=336, Percent_Identity=24.702380952381, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17555682, Length=336, Percent_Identity=24.702380952381, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71993062, Length=311, Percent_Identity=25.4019292604502, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI133931025, Length=436, Percent_Identity=21.1009174311927, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221476190, Length=441, Percent_Identity=25.3968253968254, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24585143, Length=441, Percent_Identity=25.3968253968254, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24585139, Length=441, Percent_Identity=25.3968253968254, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136594, Length=329, Percent_Identity=25.8358662613982, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573972, Length=439, Percent_Identity=24.373576309795, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24586044, Length=425, Percent_Identity=24.2352941176471, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17136190, Length=430, Percent_Identity=22.093023255814, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24585135, Length=441, Percent_Identity=22.4489795918367, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356415, Length=312, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24652373, Length=426, Percent_Identity=23.0046948356808, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24657193, Length=305, Percent_Identity=23.2786885245902, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24657185, Length=305, Percent_Identity=23.2786885245902, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24657188, Length=305, Percent_Identity=23.2786885245902, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 49964; Mature: 49833

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIASLFQEAARLAAGFRQATPARHMPTHDYATSLACFNEPLPTVGSQMLEVITQLADG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
AEPGLHATTGPRFFGWVIGGSHPVGVAADFLTSAWGQNAGNHTAAPAAAAVETVAARWLL
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DLLKLPAESSVGFVTGATVANFTCLAAARGEVLRQVGWDGDARGLFSAPEITVLIGDDAH
HHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCH
TTVFSALQFLGLGHDRVLRVRTDPVGRIDPAALAGALDMVSGPIIAILQAGQINTGAFDD
HHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHH
FAAIIPLLKAKGAWVHIDGAFGLWAQASVKTSHLSRGIEAADSWATDGHKWLQTPYDCGY
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHCCCHHCCH
AIVRNELAHRRAMTIAASYLPLAGEGERDPSHYVPELSRRARGFATWAMLKHLGREGVAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LIDQCCASARLAADLLGREPGIAILNEVTLNQLVIRFAADRPDEEGDAMTRKTIEKIQAD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
GLIFAGGAKWHGRDVLRLSVTNFQTTSDQAELAAESIIAAYRSVSGNSHQR
CEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAIASLFQEAARLAAGFRQATPARHMPTHDYATSLACFNEPLPTVGSQMLEVITQLADG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
AEPGLHATTGPRFFGWVIGGSHPVGVAADFLTSAWGQNAGNHTAAPAAAAVETVAARWLL
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
DLLKLPAESSVGFVTGATVANFTCLAAARGEVLRQVGWDGDARGLFSAPEITVLIGDDAH
HHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCH
TTVFSALQFLGLGHDRVLRVRTDPVGRIDPAALAGALDMVSGPIIAILQAGQINTGAFDD
HHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHH
FAAIIPLLKAKGAWVHIDGAFGLWAQASVKTSHLSRGIEAADSWATDGHKWLQTPYDCGY
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHCCCHHCCH
AIVRNELAHRRAMTIAASYLPLAGEGERDPSHYVPELSRRARGFATWAMLKHLGREGVAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LIDQCCASARLAADLLGREPGIAILNEVTLNQLVIRFAADRPDEEGDAMTRKTIEKIQAD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
GLIFAGGAKWHGRDVLRLSVTNFQTTSDQAELAAESIIAAYRSVSGNSHQR
CEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]