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The map label for this gene is nahR [H]

Identifier: 209549836

GI number: 209549836

Start: 2301500

End: 2302450

Strand: Direct

Name: nahR [H]

Synonym: Rleg2_2248

Alternate gene names: 209549836

Gene position: 2301500-2302450 (Clockwise)

Preceding gene: 209549832

Following gene: 209549837

Centisome position: 50.72

GC content: 65.93

Gene sequence:

>951_bases
ATGCTGAATTCAATTGACCTCTCCCGCAGCGATCTCAATCTGCTCGTGCTCTTCGAGGCGGTGCTGGAGGAGCGTCATGT
CGGCCGCGCCGCCGCGCGGCTGAACCTTACCTCTCCGGCCGTCAGCCATGGGCTGGGCCGGCTGCGGCGACTGCTGAACG
ATCCACTGTTCCTCAGAACGCCCAAGGGCGTCGTGCCGACGGCGCGCGCCATGGAACTGGCAGCACCGATCGCCGATGTG
CTCGCCCGCGTGCGAAGCATGCTTTCGGACGCCGAACCCTTCGATCCCGCAAACTCCACCCGCCGCTTCACGATCGCCGC
ACCGGACGGCGTTTCCGCCGTGCTGCTGGCGCCGCTTCTCGACAAGCTTCACCGCACCGCACCCGGCATCGATATCGGCA
TCCGCCAACTGCTGCCGGCGCCCAAGGAAACGTCGCCGGAGCGTGCATGGCGCGACGCATTCGCCGATCTCGACGACCGG
CTGACCGATATCGCGGTCATCCCCACCGAGCACATTCCGCAGCGCTTCCACGTCAGCCGGCTCTATGAGGAGGATTTCGT
CGTGGCGATGCGCACCGGCCATGCCTTCGCCGGCGAACCGACCCTGACCAGATACTGCGAGATGCAGCATCTGGTCGTCT
CGCTCAGCGGCGATCCCCATGGTTTCGTCGACGAGGCCCTGGCCAAGCACGGCTGCGCGCGGCGTGTCGCGCTGACCGTG
CCGAACTTCACATTCGCCCTCGCCATCCTCGCCGAAACCGATCTGCTCTGCGCGCTGCCGAGACGGTTTGCCGCCGTGCA
TGCGGCGCGCTTCGGACTGGAAAGCGTCAACGCGCCGCTGGAACTCACACGATTTCACATCAATGCCGCTCTGCCCAAGG
TCGCCTTGATGGATACCGGCGTCGCCTGGCTGCTGGGTGTTCTCGAGCAAACGCAACCGGCGGCGCCGTAA

Upstream 100 bases:

>100_bases
CATGACCTTGCTCCTTCAGCGATGCGAACGCCGTTTGCGCCCGCCACAGGACAGATCCCACTTCAGCGACAACTGAATCC
AATGATATGATTTCAGCGAT

Downstream 100 bases:

>100_bases
GGCCGCAAAATTCGGCAACGCCGAAGATCGATCTCATATTTTGCTGCCAAGACAGCGTCGGCAAGATCGGCTAGACTGCA
TGCGCCGACAGCTTGCGTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLNSIDLSRSDLNLLVLFEAVLEERHVGRAAARLNLTSPAVSHGLGRLRRLLNDPLFLRTPKGVVPTARAMELAAPIADV
LARVRSMLSDAEPFDPANSTRRFTIAAPDGVSAVLLAPLLDKLHRTAPGIDIGIRQLLPAPKETSPERAWRDAFADLDDR
LTDIAVIPTEHIPQRFHVSRLYEEDFVVAMRTGHAFAGEPTLTRYCEMQHLVVSLSGDPHGFVDEALAKHGCARRVALTV
PNFTFALAILAETDLLCALPRRFAAVHAARFGLESVNAPLELTRFHINAALPKVALMDTGVAWLLGVLEQTQPAAP

Sequences:

>Translated_316_residues
MLNSIDLSRSDLNLLVLFEAVLEERHVGRAAARLNLTSPAVSHGLGRLRRLLNDPLFLRTPKGVVPTARAMELAAPIADV
LARVRSMLSDAEPFDPANSTRRFTIAAPDGVSAVLLAPLLDKLHRTAPGIDIGIRQLLPAPKETSPERAWRDAFADLDDR
LTDIAVIPTEHIPQRFHVSRLYEEDFVVAMRTGHAFAGEPTLTRYCEMQHLVVSLSGDPHGFVDEALAKHGCARRVALTV
PNFTFALAILAETDLLCALPRRFAAVHAARFGLESVNAPLELTRFHINAALPKVALMDTGVAWLLGVLEQTQPAAP
>Mature_316_residues
MLNSIDLSRSDLNLLVLFEAVLEERHVGRAAARLNLTSPAVSHGLGRLRRLLNDPLFLRTPKGVVPTARAMELAAPIADV
LARVRSMLSDAEPFDPANSTRRFTIAAPDGVSAVLLAPLLDKLHRTAPGIDIGIRQLLPAPKETSPERAWRDAFADLDDR
LTDIAVIPTEHIPQRFHVSRLYEEDFVVAMRTGHAFAGEPTLTRYCEMQHLVVSLSGDPHGFVDEALAKHGCARRVALTV
PNFTFALAILAETDLLCALPRRFAAVHAARFGLESVNAPLELTRFHINAALPKVALMDTGVAWLLGVLEQTQPAAP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=304, Percent_Identity=27.3026315789474, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081766, Length=274, Percent_Identity=26.6423357664234, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786820, Length=113, Percent_Identity=35.3982300884956, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367136, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790147, Length=272, Percent_Identity=25.7352941176471, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34488; Mature: 34488

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSIDLSRSDLNLLVLFEAVLEERHVGRAAARLNLTSPAVSHGLGRLRRLLNDPLFLRT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEC
PKGVVPTARAMELAAPIADVLARVRSMLSDAEPFDPANSTRRFTIAAPDGVSAVLLAPLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
DKLHRTAPGIDIGIRQLLPAPKETSPERAWRDAFADLDDRLTDIAVIPTEHIPQRFHVSR
HHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECCHHCCHHHHHHH
LYEEDFVVAMRTGHAFAGEPTLTRYCEMQHLVVSLSGDPHGFVDEALAKHGCARRVALTV
HHCCCEEEEEECCCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCCEEEEEC
PNFTFALAILAETDLLCALPRRFAAVHAARFGLESVNAPLELTRFHINAALPKVALMDTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEHHHHCCHHHHHHCC
VAWLLGVLEQTQPAAP
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNSIDLSRSDLNLLVLFEAVLEERHVGRAAARLNLTSPAVSHGLGRLRRLLNDPLFLRT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEC
PKGVVPTARAMELAAPIADVLARVRSMLSDAEPFDPANSTRRFTIAAPDGVSAVLLAPLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
DKLHRTAPGIDIGIRQLLPAPKETSPERAWRDAFADLDDRLTDIAVIPTEHIPQRFHVSR
HHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECCHHCCHHHHHHH
LYEEDFVVAMRTGHAFAGEPTLTRYCEMQHLVVSLSGDPHGFVDEALAKHGCARRVALTV
HHCCCEEEEEECCCCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCCEEEEEC
PNFTFALAILAETDLLCALPRRFAAVHAARFGLESVNAPLELTRFHINAALPKVALMDTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEHHHHCCHHHHHHCC
VAWLLGVLEQTQPAAP
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]