Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 209549818

GI number: 209549818

Start: 2285699

End: 2286166

Strand: Reverse

Name: lrp [H]

Synonym: Rleg2_2230

Alternate gene names: 209549818

Gene position: 2286166-2285699 (Counterclockwise)

Preceding gene: 209549821

Following gene: 209549815

Centisome position: 50.38

GC content: 62.61

Gene sequence:

>468_bases
GTGCCGAACGTCCTTGATGGGATCGATCGCCATATCCTGCGCGTGCTTCAGCGCGACGGGCGCATTTCGAATGTCGAACT
GGCGAAGGAAGTGGGGCTGTCGCCTTCGCCGTGCCTGCGCCGTGTGCGGCTCTTGGAAGAGGCGGGTGTTATCGATCGCT
ATGTTGCGGTGCTGGGCCCGGCAAAGGTCGGGGCGGGGCTGACAGTTTTTGCCCGCGTATGGTTCAAGACCCAGGATGCC
GAGGTGACGCTGCGCTTCGCAGAAGCCGTCCGGCGGTTTCCCGAGGTGATGGAATGCTACCTGACGACGGGGGAATGCGA
CGCCGTTCTGCGGATCGTCACCGCCGATCTTCACAGCTATTGGCGTTTCCAGGCCGACCACCTGACCCGCATTCCGAGCG
TGCTCAGCGTCAAGACCGATGTGCCGATGGAAACGCTGAAGCGAAGCTACGAGCTGCCGGTTCGGTAG

Upstream 100 bases:

>100_bases
CAACAATAGAGCATGTCTTGCGCAATGAGCTTGCGAAGAGGCCTCAAAATTGCGAATATTTGGCATATTATGCTATTATA
AAAGAAATAGGAGCTATAAA

Downstream 100 bases:

>100_bases
GCGCGCGTGGCGCATCACACGCTCATCTACGACTTCCCATCGACTGGGAGGCCTGGCTGCGCAGCGCCGATGTCCGGGAT
GTCGATCCGACGAGCGGGCT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MPNVLDGIDRHILRVLQRDGRISNVELAKEVGLSPSPCLRRVRLLEEAGVIDRYVAVLGPAKVGAGLTVFARVWFKTQDA
EVTLRFAEAVRRFPEVMECYLTTGECDAVLRIVTADLHSYWRFQADHLTRIPSVLSVKTDVPMETLKRSYELPVR

Sequences:

>Translated_155_residues
MPNVLDGIDRHILRVLQRDGRISNVELAKEVGLSPSPCLRRVRLLEEAGVIDRYVAVLGPAKVGAGLTVFARVWFKTQDA
EVTLRFAEAVRRFPEVMECYLTTGECDAVLRIVTADLHSYWRFQADHLTRIPSVLSVKTDVPMETLKRSYELPVR
>Mature_154_residues
PNVLDGIDRHILRVLQRDGRISNVELAKEVGLSPSPCLRRVRLLEEAGVIDRYVAVLGPAKVGAGLTVFARVWFKTQDAE
VTLRFAEAVRRFPEVMECYLTTGECDAVLRIVTADLHSYWRFQADHLTRIPSVLSVKTDVPMETLKRSYELPVR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=43.7086092715232, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=34.4370860927152, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17563; Mature: 17431

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNVLDGIDRHILRVLQRDGRISNVELAKEVGLSPSPCLRRVRLLEEAGVIDRYVAVLGP
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCH
AKVGAGLTVFARVWFKTQDAEVTLRFAEAVRRFPEVMECYLTTGECDAVLRIVTADLHSY
HHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WRFQADHLTRIPSVLSVKTDVPMETLKRSYELPVR
HHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
PNVLDGIDRHILRVLQRDGRISNVELAKEVGLSPSPCLRRVRLLEEAGVIDRYVAVLGP
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCH
AKVGAGLTVFARVWFKTQDAEVTLRFAEAVRRFPEVMECYLTTGECDAVLRIVTADLHSY
HHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WRFQADHLTRIPSVLSVKTDVPMETLKRSYELPVR
HHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]