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The map label for this gene is mcpA [H]

Identifier: 209549771

GI number: 209549771

Start: 2235421

End: 2237241

Strand: Reverse

Name: mcpA [H]

Synonym: Rleg2_2181

Alternate gene names: 209549771

Gene position: 2237241-2235421 (Counterclockwise)

Preceding gene: 209549773

Following gene: 209549770

Centisome position: 49.3

GC content: 64.58

Gene sequence:

>1821_bases
ATGCGCAACATCAAGATTTCCACACGCCTTTACTGCCTCGTCGGCTTCACGCTTGCCGTGCTCGCGGCAACGATGGTGTT
CTTTCTGAACTATTCCTATTCCGAGCTGCAAGCGGAGCGGAAGGCGGGGCTGGAGAAGATGGAGGCGACGGCGATCGGCA
TCTTCGACAAATATTACAAGATGGAGCAGGCGGGCACGATGACCCGCGAGCAGGCCCAGGCGGCCGCCAAGGACGTGATC
GGTGCGATGCGCTACGGCGCAGACGGCTATTTCTGGATCAACGACATGCATCCGACCATGGTGATGCACCCGATCAAGCC
GGCGCTCAACGGCACCGACATCTCGCAGATGAAGGATCCGAACGGCAAGTTCCTGTTCGTCGAATTCGTCAACAAGGTGA
AGAAGGACGGCAAGGGCTTCGTCGATTATTACTGGCCGAAGCCGGGCGCCGACGAGCCGGTGCTAAAATATTCCTATGTC
GCCGGTTTCGAGCCCTGGGGCTGGATCGTCGGCACCGGCGTCTATGCCGATGACCTAGCCGCGCTCTATCGCCAGAATGC
GATCTGGGCGGCAGTGCTCTGCCTGCTCGGTGCGGCCGCCACTGTTGCCATCGCCTATGCCATCGTGCGCAGCGTGACGG
CGCCGATCGCCCGGCTGAAGACGGCGATGAACGCGATCGCCGCCGAAGAGGCATCGGTGGAGATCGCCGGCAGCGAGTGC
CGTGACGAAATCGGCCAGATGGCCAAGGCGCTGCTGGTGCTGCGCGATTCCGTCGACGAGCGCAGCGCGCTGCGTGGGCG
GGAAGACGAAAGACAGCGGCAGATCGAAGATGAGCGCCGCGGCAACGAGGCGAGCCTGCGTTCGGCCTCGGAGCGGCAGA
CCCTTGCGATGCAGGCGCTCGGCGTCGGCCTGGAGAAGCTCGCTGGCGGCGACCTGACGGTTGCGATCGGCGATATCGGC
GAGGACTACGCCAAGCTGAGGGGCGACTTCAACGCCGCCGTCGATGCGCTGAACGGCGTCATCCATGCGATCGCCGAGTC
GAGCAGCGTCGTCAACGACAGCGCTTCCGACATCAGCGAGGCGACCGGCAATCTTTCGAAGCGCACGGAACAGCAGGCGG
CGGCACTCGAAGAAACGGCGGCAGCGCTCGACGAGATCACCGCGACGGTCAAGACGGCATCCGAGCGGGCGAACGAGGCG
CGCGAGATGGTGGCCGAAACCAAGGCGAGCGCCGGCCGCTCCGGCGATATCGTCCGCAATGCGGTGACGGCGATGGGCCG
GATCGAGGAATCGTCGAGCCGCATCAACCAGATCATCTCGGTTATCGACGAGATCGCCTTCCAGACGAACCTTCTGGCGC
TGAATGCCGGCGTCGAGGCTGCGCGGGCAGGCGAGGCGGGCCGCGGCTTTGCCGTCGTCGCCCAGGAAGTGCGCGAACTC
GCCCAGCGTTCCGCCAATGCGGCCAAGGAGATCAAGGAATTGATCAGCCGGTCGGCGACCGAGGTCGAGGGCGGGGTGGC
GCTGGTGCGCTCGACGGGTGAGGCGTTGCTGGAGATCGAAGCGCTGGTCAACAAGGTCAACGATCACGTCGCGTCGATCG
CGACGGCGGCCCGCGAACAGTCGACCGGGCTGAACGAGATCAACGGTTCCGTCAACCATATGGACCAGATGACGCAGCAG
AATGCCGCGATGGTCGAGGAGACGACGGCGGCGAGCCGCACACTCGCCGACGAAAGCACCCAGCTGAAGACGCTGCTTTC
GAATTTCCGGCTGCGCGGGGCGGGGCAATCGCCCGGAGCCCGGTACACACGGGCAGCGTGA

Upstream 100 bases:

>100_bases
CTCACGTCATTTAATTGTCTTCTAATCAAACTTTACGCTCCAGTAATTCTGATGGGTCAGTATGTGAACGATTTCACATA
GAAGACTCGCCGGGAACCTC

Downstream 100 bases:

>100_bases
GTTAAACGACAGATCAAAGGCCGCGAAAGCGGCCTTTTTCATCTCCGTCGCGTTCAGATTGTGCCGGTAAGTTTTCATTC
ACCGTTTTTAATTAAAATTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MRNIKISTRLYCLVGFTLAVLAATMVFFLNYSYSELQAERKAGLEKMEATAIGIFDKYYKMEQAGTMTREQAQAAAKDVI
GAMRYGADGYFWINDMHPTMVMHPIKPALNGTDISQMKDPNGKFLFVEFVNKVKKDGKGFVDYYWPKPGADEPVLKYSYV
AGFEPWGWIVGTGVYADDLAALYRQNAIWAAVLCLLGAAATVAIAYAIVRSVTAPIARLKTAMNAIAAEEASVEIAGSEC
RDEIGQMAKALLVLRDSVDERSALRGREDERQRQIEDERRGNEASLRSASERQTLAMQALGVGLEKLAGGDLTVAIGDIG
EDYAKLRGDFNAAVDALNGVIHAIAESSSVVNDSASDISEATGNLSKRTEQQAAALEETAAALDEITATVKTASERANEA
REMVAETKASAGRSGDIVRNAVTAMGRIEESSSRINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
AQRSANAAKEIKELISRSATEVEGGVALVRSTGEALLEIEALVNKVNDHVASIATAAREQSTGLNEINGSVNHMDQMTQQ
NAAMVEETTAASRTLADESTQLKTLLSNFRLRGAGQSPGARYTRAA

Sequences:

>Translated_606_residues
MRNIKISTRLYCLVGFTLAVLAATMVFFLNYSYSELQAERKAGLEKMEATAIGIFDKYYKMEQAGTMTREQAQAAAKDVI
GAMRYGADGYFWINDMHPTMVMHPIKPALNGTDISQMKDPNGKFLFVEFVNKVKKDGKGFVDYYWPKPGADEPVLKYSYV
AGFEPWGWIVGTGVYADDLAALYRQNAIWAAVLCLLGAAATVAIAYAIVRSVTAPIARLKTAMNAIAAEEASVEIAGSEC
RDEIGQMAKALLVLRDSVDERSALRGREDERQRQIEDERRGNEASLRSASERQTLAMQALGVGLEKLAGGDLTVAIGDIG
EDYAKLRGDFNAAVDALNGVIHAIAESSSVVNDSASDISEATGNLSKRTEQQAAALEETAAALDEITATVKTASERANEA
REMVAETKASAGRSGDIVRNAVTAMGRIEESSSRINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
AQRSANAAKEIKELISRSATEVEGGVALVRSTGEALLEIEALVNKVNDHVASIATAAREQSTGLNEINGSVNHMDQMTQQ
NAAMVEETTAASRTLADESTQLKTLLSNFRLRGAGQSPGARYTRAA
>Mature_606_residues
MRNIKISTRLYCLVGFTLAVLAATMVFFLNYSYSELQAERKAGLEKMEATAIGIFDKYYKMEQAGTMTREQAQAAAKDVI
GAMRYGADGYFWINDMHPTMVMHPIKPALNGTDISQMKDPNGKFLFVEFVNKVKKDGKGFVDYYWPKPGADEPVLKYSYV
AGFEPWGWIVGTGVYADDLAALYRQNAIWAAVLCLLGAAATVAIAYAIVRSVTAPIARLKTAMNAIAAEEASVEIAGSEC
RDEIGQMAKALLVLRDSVDERSALRGREDERQRQIEDERRGNEASLRSASERQTLAMQALGVGLEKLAGGDLTVAIGDIG
EDYAKLRGDFNAAVDALNGVIHAIAESSSVVNDSASDISEATGNLSKRTEQQAAALEETAAALDEITATVKTASERANEA
REMVAETKASAGRSGDIVRNAVTAMGRIEESSSRINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
AQRSANAAKEIKELISRSATEVEGGVALVRSTGEALLEIEALVNKVNDHVASIATAAREQSTGLNEINGSVNHMDQMTQQ
NAAMVEETTAASRTLADESTQLKTLLSNFRLRGAGQSPGARYTRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=47.1910112359551, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1788195, Length=296, Percent_Identity=43.5810810810811, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1787690, Length=303, Percent_Identity=41.2541254125413, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1788194, Length=300, Percent_Identity=41.6666666666667, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789453, Length=244, Percent_Identity=37.2950819672131, Blast_Score=156, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65117; Mature: 65117

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIKISTRLYCLVGFTLAVLAATMVFFLNYSYSELQAERKAGLEKMEATAIGIFDKYYK
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MEQAGTMTREQAQAAAKDVIGAMRYGADGYFWINDMHPTMVMHPIKPALNGTDISQMKDP
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHEEECCCCCCCCCCHHHCCCC
NGKFLFVEFVNKVKKDGKGFVDYYWPKPGADEPVLKYSYVAGFEPWGWIVGTGVYADDLA
CCCEEHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEHHHCCCCCCCHHEECCCHHHHHH
ALYRQNAIWAAVLCLLGAAATVAIAYAIVRSVTAPIARLKTAMNAIAAEEASVEIAGSEC
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHH
RDEIGQMAKALLVLRDSVDERSALRGREDERQRQIEDERRGNEASLRSASERQTLAMQAL
HHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GVGLEKLAGGDLTVAIGDIGEDYAKLRGDFNAAVDALNGVIHAIAESSSVVNDSASDISE
HCCHHHHCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
ATGNLSKRTEQQAAALEETAAALDEITATVKTASERANEAREMVAETKASAGRSGDIVRN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AVTAMGRIEESSSRINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSANAAKEIKELISRSATEVEGGVALVRSTGEALLEIEALVNKVNDHVASIATAAREQ
HHHCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGLNEINGSVNHMDQMTQQNAAMVEETTAASRTLADESTQLKTLLSNFRLRGAGQSPGA
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCC
RYTRAA
CCCCCC
>Mature Secondary Structure
MRNIKISTRLYCLVGFTLAVLAATMVFFLNYSYSELQAERKAGLEKMEATAIGIFDKYYK
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MEQAGTMTREQAQAAAKDVIGAMRYGADGYFWINDMHPTMVMHPIKPALNGTDISQMKDP
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHEEECCCCCCCCCCHHHCCCC
NGKFLFVEFVNKVKKDGKGFVDYYWPKPGADEPVLKYSYVAGFEPWGWIVGTGVYADDLA
CCCEEHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEHHHCCCCCCCHHEECCCHHHHHH
ALYRQNAIWAAVLCLLGAAATVAIAYAIVRSVTAPIARLKTAMNAIAAEEASVEIAGSEC
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHH
RDEIGQMAKALLVLRDSVDERSALRGREDERQRQIEDERRGNEASLRSASERQTLAMQAL
HHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GVGLEKLAGGDLTVAIGDIGEDYAKLRGDFNAAVDALNGVIHAIAESSSVVNDSASDISE
HCCHHHHCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
ATGNLSKRTEQQAAALEETAAALDEITATVKTASERANEAREMVAETKASAGRSGDIVRN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AVTAMGRIEESSSRINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSANAAKEIKELISRSATEVEGGVALVRSTGEALLEIEALVNKVNDHVASIATAAREQ
HHHCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGLNEINGSVNHMDQMTQQNAAMVEETTAASRTLADESTQLKTLLSNFRLRGAGQSPGA
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCC
RYTRAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]