| Definition | Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome. |
|---|---|
| Accession | NC_011369 |
| Length | 4,537,948 |
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The map label for this gene is gno [H]
Identifier: 209549728
GI number: 209549728
Start: 2197348
End: 2198118
Strand: Reverse
Name: gno [H]
Synonym: Rleg2_2136
Alternate gene names: 209549728
Gene position: 2198118-2197348 (Counterclockwise)
Preceding gene: 209549729
Following gene: 209549726
Centisome position: 48.44
GC content: 64.59
Gene sequence:
>771_bases ATGAGCATATCGGATAGATTTTCATTGGCGGGTCAGGTGGCGCTCGTGACCGGTGGCGGCCGCGGTCTGGGCTTCGAGAT GGCGCGGGTGCTTGCCGAGGCCGGCGCGCATGTCATCGTCACCGGACGCACAGCGGCGACGCTGGAGGAGGCCGTAAGCA CGCTGCGTGCGGCGGGCGGCTCGGCGGAGGCTGCCGTGTTCGACATCGCCGACCGAAAGGCCCAGCGTGCTGTGATGGTC GATATCGAAAAGGTTCACGGCCGTCTCGATATTCTGATCAATAATGTCGGCGCCCGCGACAGGCGGCCGCTGACCGAATT CGACGATGATGGCATCATCGAGCTGCTGCGCACCGATCTGGCCGCGGCGATGATGCTTTCGCGCGATGCCGCGGTGCTGA TGAAGCGGCGCAATTATGGCCGCCTGATCGCGGTGACCTCGATCAGCGGTCATGTCGTCATGCCCGGCGACTGCGTCTAT CCGGCTGCCAAGCAGGGCCTGACCGGACTGATGCGCGGCATGGCGGTCGAATTCGGCCCTTACGGTATCACCAGCAACGC GATTGCACCCGGCTGGTTCGCCACGGAGACGAACGCGGAAATGGCCGCGAATGAGGAATTGATGCCCTTCGTGCGCCAGC GCATCCCGGTCCAACGCTGGGGACGCCCGGACGAGATCGCCGGCGCTGCGCTGTTTCTTGCAAGCGGCGCCGCCTCCTTC GTCAACGGCCATGTATTGACTGTCGACGGCGGCATGACGGTCAGGATGTGA
Upstream 100 bases:
>100_bases CCGGGCTGCTCGGTTAGGCTGCCCCTCTTTGTACTCTTGCCAAATTAGTTGACTGAGTCCATTAAATCTCGCGGCGAGAC CGGTTGAGAGCGATGAAACC
Downstream 100 bases:
>100_bases GGAGATACCCGCCGGCGTTGTGCCGGCTTCGGATGAAAAGACTTGCCGTTGATAACGGCTGGAAATATCGGCTTGGCGCG ACTATCAATTAATAGGGCGT
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 256; Mature: 255
Protein sequence:
>256_residues MSISDRFSLAGQVALVTGGGRGLGFEMARVLAEAGAHVIVTGRTAATLEEAVSTLRAAGGSAEAAVFDIADRKAQRAVMV DIEKVHGRLDILINNVGARDRRPLTEFDDDGIIELLRTDLAAAMMLSRDAAVLMKRRNYGRLIAVTSISGHVVMPGDCVY PAAKQGLTGLMRGMAVEFGPYGITSNAIAPGWFATETNAEMAANEELMPFVRQRIPVQRWGRPDEIAGAALFLASGAASF VNGHVLTVDGGMTVRM
Sequences:
>Translated_256_residues MSISDRFSLAGQVALVTGGGRGLGFEMARVLAEAGAHVIVTGRTAATLEEAVSTLRAAGGSAEAAVFDIADRKAQRAVMV DIEKVHGRLDILINNVGARDRRPLTEFDDDGIIELLRTDLAAAMMLSRDAAVLMKRRNYGRLIAVTSISGHVVMPGDCVY PAAKQGLTGLMRGMAVEFGPYGITSNAIAPGWFATETNAEMAANEELMPFVRQRIPVQRWGRPDEIAGAALFLASGAASF VNGHVLTVDGGMTVRM >Mature_255_residues SISDRFSLAGQVALVTGGGRGLGFEMARVLAEAGAHVIVTGRTAATLEEAVSTLRAAGGSAEAAVFDIADRKAQRAVMVD IEKVHGRLDILINNVGARDRRPLTEFDDDGIIELLRTDLAAAMMLSRDAAVLMKRRNYGRLIAVTSISGHVVMPGDCVYP AAKQGLTGLMRGMAVEFGPYGITSNAIAPGWFATETNAEMAANEELMPFVRQRIPVQRWGRPDEIAGAALFLASGAASFV NGHVLTVDGGMTVRM
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=29.4117647058824, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=30.8641975308642, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=27.5193798449612, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.3643724696356, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=26.2548262548263, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.9595141700405, Blast_Score=94, Evalue=8e-20, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=28.1632653061224, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=28.3505154639175, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=30.2127659574468, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=25.3886010362694, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=26.8, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=29.4736842105263, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI32455239, Length=172, Percent_Identity=30.2325581395349, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI5031765, Length=172, Percent_Identity=30.2325581395349, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503301, Length=260, Percent_Identity=28.8461538461538, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI223718074, Length=194, Percent_Identity=30.9278350515464, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI209862901, Length=220, Percent_Identity=28.6363636363636, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI19923983, Length=220, Percent_Identity=28.6363636363636, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI142976729, Length=193, Percent_Identity=23.3160621761658, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI7657478, Length=206, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=37.6984126984127, Blast_Score=172, Evalue=1e-44, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=34.7490347490347, Blast_Score=140, Evalue=8e-35, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=33.201581027668, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=32.2448979591837, Blast_Score=114, Evalue=8e-27, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=33.203125, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=29.1338582677165, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=33.6065573770492, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.6122448979592, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25.7692307692308, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=27.34375, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.1255060728745, Blast_Score=75, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30.4, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=31.6176470588235, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=29.4776119402985, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=32.9588014981273, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=30.5970149253731, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=30.6818181818182, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=31.3432835820896, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=28.8617886178862, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=30.03663003663, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=28.4644194756554, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=31.1111111111111, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=29.5019157088123, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.2258064516129, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=28.0769230769231, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=29.7101449275362, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=26.9076305220884, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=28.7822878228782, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=29.2592592592593, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=30, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=24.8995983935743, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.9693486590038, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=26.2096774193548, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=26.2745098039216, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=26.0223048327138, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17568967, Length=202, Percent_Identity=32.1782178217822, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.4611398963731, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71982365, Length=201, Percent_Identity=28.8557213930348, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17558628, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=31.9230769230769, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17555612, Length=220, Percent_Identity=30.4545454545455, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI71997099, Length=250, Percent_Identity=30, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI193203117, Length=172, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538182, Length=260, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203115, Length=173, Percent_Identity=26.0115606936416, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.3787878787879, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=5e-18, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=31.0880829015544, Blast_Score=83, Evalue=5e-17, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=27.3809523809524, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=31.3253012048193, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=32.1428571428571, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=30.859375, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=29.4117647058824, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.4820717131474, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=27.6422764227642, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=34.5, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=30.9941520467836, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI28574402, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=27.8409090909091, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24584744, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI161076933, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=28.9340101522843, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584748, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584752, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24640492, Length=168, Percent_Identity=25.5952380952381, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571387, Length=206, Percent_Identity=30.5825242718447, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI116007236, Length=247, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27130; Mature: 26998
Theoretical pI: Translated: 6.53; Mature: 6.53
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 5.1 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.7 %Met (Mature Protein) 5.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSISDRFSLAGQVALVTGGGRGLGFEMARVLAEAGAHVIVTGRTAATLEEAVSTLRAAGG CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCC SAEAAVFDIADRKAQRAVMVDIEKVHGRLDILINNVGARDRRPLTEFDDDGIIELLRTDL CCCEEEEEHHHHHHHHHHEEEHHHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH AAAMMLSRDAAVLMKRRNYGRLIAVTSISGHVVMPGDCVYPAAKQGLTGLMRGMAVEFGP HHHHHHCCCHHHHHHHCCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHEEECCC YGITSNAIAPGWFATETNAEMAANEELMPFVRQRIPVQRWGRPDEIAGAALFLASGAASF CCCCCCCCCCCEEEECCCCHHHCCCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCHHH VNGHVLTVDGGMTVRM HCCEEEEECCCEEEEC >Mature Secondary Structure SISDRFSLAGQVALVTGGGRGLGFEMARVLAEAGAHVIVTGRTAATLEEAVSTLRAAGG CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCC SAEAAVFDIADRKAQRAVMVDIEKVHGRLDILINNVGARDRRPLTEFDDDGIIELLRTDL CCCEEEEEHHHHHHHHHHEEEHHHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH AAAMMLSRDAAVLMKRRNYGRLIAVTSISGHVVMPGDCVYPAAKQGLTGLMRGMAVEFGP HHHHHHCCCHHHHHHHCCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHEEECCC YGITSNAIAPGWFATETNAEMAANEELMPFVRQRIPVQRWGRPDEIAGAALFLASGAASF CCCCCCCCCCCEEEECCCCHHHCCCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCHHH VNGHVLTVDGGMTVRM HCCEEEEECCCEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]