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The map label for this gene is cobU [H]

Identifier: 209549726

GI number: 209549726

Start: 2192693

End: 2193217

Strand: Reverse

Name: cobU [H]

Synonym: Rleg2_2133

Alternate gene names: 209549726

Gene position: 2193217-2192693 (Counterclockwise)

Preceding gene: 209549728

Following gene: 209549725

Centisome position: 48.33

GC content: 61.52

Gene sequence:

>525_bases
ATGACGACCGCTTCCGCCAATACAGTCTTCATCCTCGGCGGCGCACGCTCCGGCAAATCCCGCTTTGCCGAAAACCTTGT
CGTTTCAACCGGCCTCGACCGCCACTATCTCGCGACCGGGCGGGCCTGGGACGAGGAGATGCAGGCGCGCATTGCCCAAC
ACAGGGCCGATCGCGGCCCATCATGGACGACGCATGAGGAGCCGCTCGATCTCGTCGGCAAGCTCGCCGCCATCGATGGT
GAGGACCGCGTCGTGCTGATCGACTGCCTGACGCTCTGGGTTACCAATCTGATGATGGAGCAGCGCGATATGGCCGGAGA
ATTTTTCGCGCTCGCCGATTATTTGCCGCGGGCAAAGGCGCGGCTTGTTTTCGTTTCCAACGAGGTCGGCCTTGGCATCG
TGCCGGACAATCGGATGGCGCGGGATTTTCGCGATCATGCCGGCCGGCTCCACCAGATGATCGCGGCAAAGGCCGCCGAA
GTCTATTTTATCGCGGCAGGCCTGCCGCTGAAAATGAAGGGTTAA

Upstream 100 bases:

>100_bases
TTCACGGCGCGGACGCGCCGTGGCTGGATTCCTGTGACAAGCACAGGAATGAGGGAAGAGAGCGGGGCGAAGCTGCGGTT
TCTCTGGAGGTCGCCTGCTC

Downstream 100 bases:

>100_bases
ATCCATGAACCAGCAAAAGATTCCCGCAACCGTCATCACCGGCTTCCTCGGCGCCGGCAAGACGACGATGATCCGCAATC
TGCTGACCAATGCCGGCGGC

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTTASANTVFILGGARSGKSRFAENLVVSTGLDRHYLATGRAWDEEMQARIAQHRADRGPSWTTHEEPLDLVGKLAAIDG
EDRVVLIDCLTLWVTNLMMEQRDMAGEFFALADYLPRAKARLVFVSNEVGLGIVPDNRMARDFRDHAGRLHQMIAAKAAE
VYFIAAGLPLKMKG

Sequences:

>Translated_174_residues
MTTASANTVFILGGARSGKSRFAENLVVSTGLDRHYLATGRAWDEEMQARIAQHRADRGPSWTTHEEPLDLVGKLAAIDG
EDRVVLIDCLTLWVTNLMMEQRDMAGEFFALADYLPRAKARLVFVSNEVGLGIVPDNRMARDFRDHAGRLHQMIAAKAAE
VYFIAAGLPLKMKG
>Mature_173_residues
TTASANTVFILGGARSGKSRFAENLVVSTGLDRHYLATGRAWDEEMQARIAQHRADRGPSWTTHEEPLDLVGKLAAIDGE
DRVVLIDCLTLWVTNLMMEQRDMAGEFFALADYLPRAKARLVFVSNEVGLGIVPDNRMARDFRDHAGRLHQMIAAKAAEV
YFIAAGLPLKMKG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=180, Percent_Identity=38.8888888888889, Blast_Score=120, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19243; Mature: 19112

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASANTVFILGGARSGKSRFAENLVVSTGLDRHYLATGRAWDEEMQARIAQHRADRGP
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCC
SWTTHEEPLDLVGKLAAIDGEDRVVLIDCLTLWVTNLMMEQRDMAGEFFALADYLPRAKA
CCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
RLVFVSNEVGLGIVPDNRMARDFRDHAGRLHQMIAAKAAEVYFIAAGLPLKMKG
EEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEECC
>Mature Secondary Structure 
TTASANTVFILGGARSGKSRFAENLVVSTGLDRHYLATGRAWDEEMQARIAQHRADRGP
CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCC
SWTTHEEPLDLVGKLAAIDGEDRVVLIDCLTLWVTNLMMEQRDMAGEFFALADYLPRAKA
CCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
RLVFVSNEVGLGIVPDNRMARDFRDHAGRLHQMIAAKAAEVYFIAAGLPLKMKG
EEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]