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The map label for this gene is yccK [H]

Identifier: 209549640

GI number: 209549640

Start: 2110274

End: 2111263

Strand: Direct

Name: yccK [H]

Synonym: Rleg2_2047

Alternate gene names: 209549640

Gene position: 2110274-2111263 (Clockwise)

Preceding gene: 209549639

Following gene: 209549646

Centisome position: 46.5

GC content: 61.92

Gene sequence:

>990_bases
ATGCATAAGCGTGAACTCGGAAAGAGCGGTCTCGAAGTCTCGGCCATCGGTCTCGGCTGCATGGGGCTAAGTTATGGATA
TGGCCCAGCGACAGATATCCAGGAAGCCGTCGCGCTGATCCGGCAGGCGGTCGAACGTGGCGTGACCTTCTTCGACACCG
CGGAAGCCTACGGCCCCTATAGAAACGAAGAGCTTTTGGGAGAAGCACTTGCTCCCTTTCGCAGCGAGGTAGTGATCGCC
ACCAAATTCGGCTTCAACTTCGATGCCAATGGCGGCCAGAGTGGCATGAACAGCCGGCCCGAGCAGATCCGGGCAGTTGC
CGACCAGGCGTTGAAGCGCTTGAAGACCGATGTCATCGATCTGTTCTACCAGCATCGCGTCGATCCGGATGTTCCGATCG
AGGACGTCGCTGGCACGGTCAAGGCGCTGATTTCAGAAGGCAAGGTGAAGCATTTCGGCCTCTCGGAAGCCGGCTCCAAG
ACGATCCGCCGCGCCCATGCCGTTCAGCCGGTGGCGGCGCTGCAGAGCGAATATTCGCTCTGGTGGCGCGAGCCCGAGCA
GGATATCCTGCCGGTGCTCGAAGAGCTCGGCATCGGCTTCGTGCCGTTCAGCCCGCTCGGCAAGGGCTTCCTCACCGGCG
CGATCAGCGAAACCACAACCTTCGACAGCAAGGACTTCCGCAACATCGTGCCGCGCTTTTCACCGGAAGCGCGAAAGGCC
AACCAGGCGCTCGTCGATCTCCTCGCAGAGATCGCCGCGCGCAAGCAGGCGACCTCCGCCCAGGTGGCGCTCGCCTGGCT
GCTGGCGCAAAAACCCTGGATCGTGCCGATCCCCGGCACCACCAAGCTGCATCGCCTGGAGGAGAATATCCGGGCCGCCG
AGGTCGAACTGACGGCGGAGGATCTCGGCAATATCGAAAGCGCGCTCGCCACCATCAAGGTGGAAGGCGATCGATATCCC
GCGCATCTGCAGGCAAGGGTCAATCGCTGA

Upstream 100 bases:

>100_bases
ATGACCCATATCGCCATCCAGGAACAGCTCGACGGCAAGGTGGTCGACTGGATGGAGCATGTCACTGACAGCGAGTACCA
AGCTTAGAAAGGAAAAGGCG

Downstream 100 bases:

>100_bases
GAACAGAAGCGGCCGCCATCATGTGCGGCCGCTCTTCATTGATCGCATCACCGTCTCGGCGCCGGCGCATTCTCCTCGAA
AGCCGGGATCGCCTCGAGCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MHKRELGKSGLEVSAIGLGCMGLSYGYGPATDIQEAVALIRQAVERGVTFFDTAEAYGPYRNEELLGEALAPFRSEVVIA
TKFGFNFDANGGQSGMNSRPEQIRAVADQALKRLKTDVIDLFYQHRVDPDVPIEDVAGTVKALISEGKVKHFGLSEAGSK
TIRRAHAVQPVAALQSEYSLWWREPEQDILPVLEELGIGFVPFSPLGKGFLTGAISETTTFDSKDFRNIVPRFSPEARKA
NQALVDLLAEIAARKQATSAQVALAWLLAQKPWIVPIPGTTKLHRLEENIRAAEVELTAEDLGNIESALATIKVEGDRYP
AHLQARVNR

Sequences:

>Translated_329_residues
MHKRELGKSGLEVSAIGLGCMGLSYGYGPATDIQEAVALIRQAVERGVTFFDTAEAYGPYRNEELLGEALAPFRSEVVIA
TKFGFNFDANGGQSGMNSRPEQIRAVADQALKRLKTDVIDLFYQHRVDPDVPIEDVAGTVKALISEGKVKHFGLSEAGSK
TIRRAHAVQPVAALQSEYSLWWREPEQDILPVLEELGIGFVPFSPLGKGFLTGAISETTTFDSKDFRNIVPRFSPEARKA
NQALVDLLAEIAARKQATSAQVALAWLLAQKPWIVPIPGTTKLHRLEENIRAAEVELTAEDLGNIESALATIKVEGDRYP
AHLQARVNR
>Mature_329_residues
MHKRELGKSGLEVSAIGLGCMGLSYGYGPATDIQEAVALIRQAVERGVTFFDTAEAYGPYRNEELLGEALAPFRSEVVIA
TKFGFNFDANGGQSGMNSRPEQIRAVADQALKRLKTDVIDLFYQHRVDPDVPIEDVAGTVKALISEGKVKHFGLSEAGSK
TIRRAHAVQPVAALQSEYSLWWREPEQDILPVLEELGIGFVPFSPLGKGFLTGAISETTTFDSKDFRNIVPRFSPEARKA
NQALVDLLAEIAARKQATSAQVALAWLLAQKPWIVPIPGTTKLHRLEENIRAAEVELTAEDLGNIESALATIKVEGDRYP
AHLQARVNR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=30.6748466257669, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436966, Length=326, Percent_Identity=30.6748466257669, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=30.6748466257669, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=30.3030303030303, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436969, Length=327, Percent_Identity=30.2752293577982, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=30.2469135802469, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI223718702, Length=295, Percent_Identity=28.4745762711864, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI41327764, Length=199, Percent_Identity=30.6532663316583, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI41152114, Length=308, Percent_Identity=27.5974025974026, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=31.974921630094, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=31.2883435582822, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=29.483282674772, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=30.0653594771242, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788081, Length=275, Percent_Identity=26.9090909090909, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=27.5071633237822, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI48994888, Length=294, Percent_Identity=29.2517006802721, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=27.0588235294118, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=26.9349845201238, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=351, Percent_Identity=28.7749287749288, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=25.2559726962457, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=25.4355400696864, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=25, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640980, Length=324, Percent_Identity=26.2345679012346, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45549126, Length=321, Percent_Identity=26.4797507788162, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646155, Length=163, Percent_Identity=32.5153374233129, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=26.3392857142857, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36004; Mature: 36004

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKRELGKSGLEVSAIGLGCMGLSYGYGPATDIQEAVALIRQAVERGVTFFDTAEAYGPY
CCCHHHCCCCCEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCC
RNEELLGEALAPFRSEVVIATKFGFNFDANGGQSGMNSRPEQIRAVADQALKRLKTDVID
CCHHHHHHHHCCHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFYQHRVDPDVPIEDVAGTVKALISEGKVKHFGLSEAGSKTIRRAHAVQPVAALQSEYSL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WWREPEQDILPVLEELGIGFVPFSPLGKGFLTGAISETTTFDSKDFRNIVPRFSPEARKA
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHH
NQALVDLLAEIAARKQATSAQVALAWLLAQKPWIVPIPGTTKLHRLEENIRAAEVELTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHEEECHH
DLGNIESALATIKVEGDRYPAHLQARVNR
HHCCHHHHHEEEEECCCCCCHHHHEECCC
>Mature Secondary Structure
MHKRELGKSGLEVSAIGLGCMGLSYGYGPATDIQEAVALIRQAVERGVTFFDTAEAYGPY
CCCHHHCCCCCEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCC
RNEELLGEALAPFRSEVVIATKFGFNFDANGGQSGMNSRPEQIRAVADQALKRLKTDVID
CCHHHHHHHHCCHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFYQHRVDPDVPIEDVAGTVKALISEGKVKHFGLSEAGSKTIRRAHAVQPVAALQSEYSL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WWREPEQDILPVLEELGIGFVPFSPLGKGFLTGAISETTTFDSKDFRNIVPRFSPEARKA
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHH
NQALVDLLAEIAARKQATSAQVALAWLLAQKPWIVPIPGTTKLHRLEENIRAAEVELTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHEEECHH
DLGNIESALATIKVEGDRYPAHLQARVNR
HHCCHHHHHEEEEECCCCCCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]