Click here to switch to the map view.

The map label for this gene is suhB [H]

Identifier: 209549538

GI number: 209549538

Start: 1987795

End: 1988622

Strand: Reverse

Name: suhB [H]

Synonym: Rleg2_1944

Alternate gene names: 209549538

Gene position: 1988622-1987795 (Counterclockwise)

Preceding gene: 209549539

Following gene: 209549537

Centisome position: 43.82

GC content: 62.92

Gene sequence:

>828_bases
ATGACCATTTCAGATCAGGATATTCTCTTTCTCGGCGATTGCGTGAAGGAGGCGGCACGCGCGGAAATCATGCCGCGGTT
CCGCAATCTCGGCGCCGCCGACGTTTCAGAAAAGACCTCGGCAATCGACGTGGTGACGCAGGCCGATCTGCTCGCCGAAC
ACCGGATCACCGCGGCGCTGAAAGAGCGCTTTCCCGCAGCCCTCGTCGTGGGTGAGGAAGCCTATGACGCCGACCGGTCC
GTCGTGCCGGCCCTTGCCGATGCCGAGCTTGCCTTCGTCATCGACCCTGTCGACGGCACCTTCAATTTTGCCGCCGGGCT
TCCCGTCTTCGGGACGATGCTCGCGGCCACCGTCAGGGGCGAGACGGTCGCCGGCATCATTTACGATCCCGTTCTCGGCG
ACACCGTGACGGCGATCAAAGGGGCGGGCGCCTTCCTGACGCGGCAGGATGGGCAATCGAGCAGACTGAGGGTTGCTGAG
CCTGCCGCTTTGAACCAGATGGTCGGCGGCATCTCTTGGGGCCATATGGACGACCCGGACCGCTCGCGCATTGCAGCCAA
CATGGCGAAGATCAGGATGACCTTCGCCTTCAACTGCTCGGCCTATGAATATTGGATGGTCGCCTCCGGCAAACTGCATT
TCATCGGCCATGCGAAGCTGATGCCCTGGGATCACCTAGCCGGCGTGCTCGCGCATCAGGAGTCCGGCGGCTATACGGCG
AGATTCGACGGTACGCCCTATCGCCCCGGCGAGACGACGGGCGGCATCATCTCCGCACCCGACAGAGAAAGCTGGCAGCT
GATCCGGCGGGAGATCATCGGCATCTGA

Upstream 100 bases:

>100_bases
CTCGATCCGAAACTCTTCGACTTTTCCACCCTTGGTGTCACCGATCCTTCATGAAAGTCCGGCTAAGCAGCTGGCTATTG
CATGAAGCGCAGGAATTCGC

Downstream 100 bases:

>100_bases
TTTGGGCCCTTAGCGAGAGGCCGGACCGAAAGGATTTGACATGACTGCGACTGTCGACGTGACCGTTCTTGCCGATCTCT
TGCGCCGTGCGGCGAAAGCG

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTISDQDILFLGDCVKEAARAEIMPRFRNLGAADVSEKTSAIDVVTQADLLAEHRITAALKERFPAALVVGEEAYDADRS
VVPALADAELAFVIDPVDGTFNFAAGLPVFGTMLAATVRGETVAGIIYDPVLGDTVTAIKGAGAFLTRQDGQSSRLRVAE
PAALNQMVGGISWGHMDDPDRSRIAANMAKIRMTFAFNCSAYEYWMVASGKLHFIGHAKLMPWDHLAGVLAHQESGGYTA
RFDGTPYRPGETTGGIISAPDRESWQLIRREIIGI

Sequences:

>Translated_275_residues
MTISDQDILFLGDCVKEAARAEIMPRFRNLGAADVSEKTSAIDVVTQADLLAEHRITAALKERFPAALVVGEEAYDADRS
VVPALADAELAFVIDPVDGTFNFAAGLPVFGTMLAATVRGETVAGIIYDPVLGDTVTAIKGAGAFLTRQDGQSSRLRVAE
PAALNQMVGGISWGHMDDPDRSRIAANMAKIRMTFAFNCSAYEYWMVASGKLHFIGHAKLMPWDHLAGVLAHQESGGYTA
RFDGTPYRPGETTGGIISAPDRESWQLIRREIIGI
>Mature_274_residues
TISDQDILFLGDCVKEAARAEIMPRFRNLGAADVSEKTSAIDVVTQADLLAEHRITAALKERFPAALVVGEEAYDADRSV
VPALADAELAFVIDPVDGTFNFAAGLPVFGTMLAATVRGETVAGIIYDPVLGDTVTAIKGAGAFLTRQDGQSSRLRVAEP
AALNQMVGGISWGHMDDPDRSRIAANMAKIRMTFAFNCSAYEYWMVASGKLHFIGHAKLMPWDHLAGVLAHQESGGYTAR
FDGTPYRPGETTGGIISAPDRESWQLIRREIIGI

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=218, Percent_Identity=31.1926605504587, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI5031789, Length=267, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221625487, Length=267, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221625507, Length=144, Percent_Identity=31.9444444444444, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788882, Length=231, Percent_Identity=27.7056277056277, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=217, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320493, Length=248, Percent_Identity=26.6129032258064, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321836, Length=214, Percent_Identity=28.0373831775701, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24664926, Length=215, Percent_Identity=29.3023255813954, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24664922, Length=205, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357957, Length=226, Percent_Identity=27.8761061946903, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24664918, Length=225, Percent_Identity=26.2222222222222, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357303, Length=243, Percent_Identity=29.2181069958848, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21357329, Length=230, Percent_Identity=29.1304347826087, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29614; Mature: 29483

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISDQDILFLGDCVKEAARAEIMPRFRNLGAADVSEKTSAIDVVTQADLLAEHRITAAL
CCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KERFPAALVVGEEAYDADRSVVPALADAELAFVIDPVDGTFNFAAGLPVFGTMLAATVRG
HHHCCEEEEECCHHHCCCCCCCCHHCCCEEEEEEECCCCCEEHHCCCHHHHHHHHHHHCC
ETVAGIIYDPVLGDTVTAIKGAGAFLTRQDGQSSRLRVAEPAALNQMVGGISWGHMDDPD
CEEEEEEECCCCCCHHHHHHCCCEEEECCCCCCCCEEEECCHHHHHHHCCCCCCCCCCCH
RSRIAANMAKIRMTFAFNCSAYEYWMVASGKLHFIGHAKLMPWDHLAGVLAHQESGGYTA
HHHHHHHHEEEEEEEEECCCCEEEEEEECCEEEEEECCCCCCHHHHHHHHHCCCCCCEEE
RFDGTPYRPGETTGGIISAPDRESWQLIRREIIGI
EECCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TISDQDILFLGDCVKEAARAEIMPRFRNLGAADVSEKTSAIDVVTQADLLAEHRITAAL
CCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KERFPAALVVGEEAYDADRSVVPALADAELAFVIDPVDGTFNFAAGLPVFGTMLAATVRG
HHHCCEEEEECCHHHCCCCCCCCHHCCCEEEEEEECCCCCEEHHCCCHHHHHHHHHHHCC
ETVAGIIYDPVLGDTVTAIKGAGAFLTRQDGQSSRLRVAEPAALNQMVGGISWGHMDDPD
CEEEEEEECCCCCCHHHHHHCCCEEEECCCCCCCCEEEECCHHHHHHHCCCCCCCCCCCH
RSRIAANMAKIRMTFAFNCSAYEYWMVASGKLHFIGHAKLMPWDHLAGVLAHQESGGYTA
HHHHHHHHEEEEEEEEECCCCEEEEEEECCEEEEEECCCCCCHHHHHHHHHCCCCCCEEE
RFDGTPYRPGETTGGIISAPDRESWQLIRREIIGI
EECCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]