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The map label for this gene is suhB [H]

Identifier: 209549537

GI number: 209549537

Start: 1986930

End: 1987754

Strand: Reverse

Name: suhB [H]

Synonym: Rleg2_1943

Alternate gene names: 209549537

Gene position: 1987754-1986930 (Counterclockwise)

Preceding gene: 209549538

Following gene: 209549530

Centisome position: 43.8

GC content: 65.82

Gene sequence:

>825_bases
ATGACTGCGACTGTCGACGTGACCGTTCTTGCCGATCTCTTGCGCCGTGCGGCGAAAGCGGAGATCCTGCCGCGCTTCCG
CCGGCTCGGTGAGAATGACGTGCGCGCCAAGAGCGAGGCGACCGATCTCGTCACCGAGGCCGACGAGCAGGCCGAGCGGA
TGATCAAGGCGGAAGCAGAGCGGCTTTGGCCGGGGGCGTTGTTCGTCGGTGAAGAAACGGTCGCAGCCGAGCCGGCATTG
CTCGGCAGGCTCGCAGATGCCGATCTCGCCATTGTCGTCGACCCGGTCGACGGCACGTTCAATTTCGCCGCCGGCATCCC
GGCCTTTGGTGTCATGGCCTCGGTCATTTCAGGCGGCGAGACTATTGCCGGCATCATCTACGATCCAATGGGCGATGACT
GGGTGATGGCGGAAAAGGGAGCCGGCGCCTGGCTGCGGCGGCCGGATGGCGAAGCACGGCGGCTGCGCGCGGCCGAGCCT
GTCGCGCTCGACCAGATGGTCGGCATGGCCTCGACAGGCTACCTGCCGCAGGAGAAGCGGGCCGAGATCCTCGGCAATCT
CGCCAAGGTCCGCTTCCTCACCAACTACCGCTGTGCCGCCCATGAATACCGCACCCTTGCCGGCGGCCATGTGCATTACC
TGATGTACAACAAGCTGATGCCCTGGGACCATCTGGCCGGCACGCTGATCTCGCAGGAAGCCGGCGCTTATGCCGCCCGC
TTCGACGGCTCGCCCTACCTGCCGCATCATCTCGATGGCGGGCTGCTGGTTGCGCCCGACAAGGCATCGTGGGACGTGCT
GCGCCGTGAGGTCGTCACGGTCTGA

Upstream 100 bases:

>100_bases
ATCTCCGCACCCGACAGAGAAAGCTGGCAGCTGATCCGGCGGGAGATCATCGGCATCTGATTTGGGCCCTTAGCGAGAGG
CCGGACCGAAAGGATTTGAC

Downstream 100 bases:

>100_bases
ACGCATGAAACCAGCCGCAGGCCACTGATTTTGCGGCTGGATTCTGAGACGGGGAGGCTGGCTTCGTTCGATAACGCGTA
TCGGTGGTTCGGCCCTACTC

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTATVDVTVLADLLRRAAKAEILPRFRRLGENDVRAKSEATDLVTEADEQAERMIKAEAERLWPGALFVGEETVAAEPAL
LGRLADADLAIVVDPVDGTFNFAAGIPAFGVMASVISGGETIAGIIYDPMGDDWVMAEKGAGAWLRRPDGEARRLRAAEP
VALDQMVGMASTGYLPQEKRAEILGNLAKVRFLTNYRCAAHEYRTLAGGHVHYLMYNKLMPWDHLAGTLISQEAGAYAAR
FDGSPYLPHHLDGGLLVAPDKASWDVLRREVVTV

Sequences:

>Translated_274_residues
MTATVDVTVLADLLRRAAKAEILPRFRRLGENDVRAKSEATDLVTEADEQAERMIKAEAERLWPGALFVGEETVAAEPAL
LGRLADADLAIVVDPVDGTFNFAAGIPAFGVMASVISGGETIAGIIYDPMGDDWVMAEKGAGAWLRRPDGEARRLRAAEP
VALDQMVGMASTGYLPQEKRAEILGNLAKVRFLTNYRCAAHEYRTLAGGHVHYLMYNKLMPWDHLAGTLISQEAGAYAAR
FDGSPYLPHHLDGGLLVAPDKASWDVLRREVVTV
>Mature_273_residues
TATVDVTVLADLLRRAAKAEILPRFRRLGENDVRAKSEATDLVTEADEQAERMIKAEAERLWPGALFVGEETVAAEPALL
GRLADADLAIVVDPVDGTFNFAAGIPAFGVMASVISGGETIAGIIYDPMGDDWVMAEKGAGAWLRRPDGEARRLRAAEPV
ALDQMVGMASTGYLPQEKRAEILGNLAKVRFLTNYRCAAHEYRTLAGGHVHYLMYNKLMPWDHLAGTLISQEAGAYAARF
DGSPYLPHHLDGGLLVAPDKASWDVLRREVVTV

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=222, Percent_Identity=26.1261261261261, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031789, Length=228, Percent_Identity=24.5614035087719, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788882, Length=216, Percent_Identity=30.0925925925926, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI193202572, Length=227, Percent_Identity=28.1938325991189, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=226, Percent_Identity=26.5486725663717, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321836, Length=247, Percent_Identity=24.2914979757085, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=26.4423076923077, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357957, Length=226, Percent_Identity=24.7787610619469, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24664922, Length=222, Percent_Identity=28.8288288288288, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24664926, Length=221, Percent_Identity=29.8642533936652, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29755; Mature: 29624

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATVDVTVLADLLRRAAKAEILPRFRRLGENDVRAKSEATDLVTEADEQAERMIKAEAE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLWPGALFVGEETVAAEPALLGRLADADLAIVVDPVDGTFNFAAGIPAFGVMASVISGGE
HCCCCEEEECCCHHHCCHHHHHHHCCCCEEEEEECCCCCEEHHCCCCHHHHHHHHHCCCC
TIAGIIYDPMGDDWVMAEKGAGAWLRRPDGEARRLRAAEPVALDQMVGMASTGYLPQEKR
EEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHH
AEILGNLAKVRFLTNYRCAAHEYRTLAGGHVHYLMYNKLMPWDHLAGTLISQEAGAYAAR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
FDGSPYLPHHLDGGLLVAPDKASWDVLRREVVTV
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TATVDVTVLADLLRRAAKAEILPRFRRLGENDVRAKSEATDLVTEADEQAERMIKAEAE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLWPGALFVGEETVAAEPALLGRLADADLAIVVDPVDGTFNFAAGIPAFGVMASVISGGE
HCCCCEEEECCCHHHCCHHHHHHHCCCCEEEEEECCCCCEEHHCCCCHHHHHHHHHCCCC
TIAGIIYDPMGDDWVMAEKGAGAWLRRPDGEARRLRAAEPVALDQMVGMASTGYLPQEKR
EEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHH
AEILGNLAKVRFLTNYRCAAHEYRTLAGGHVHYLMYNKLMPWDHLAGTLISQEAGAYAAR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
FDGSPYLPHHLDGGLLVAPDKASWDVLRREVVTV
CCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]