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The map label for this gene is moaC [H]

Identifier: 209549417

GI number: 209549417

Start: 1869931

End: 1870428

Strand: Direct

Name: moaC [H]

Synonym: Rleg2_1823

Alternate gene names: 209549417

Gene position: 1869931-1870428 (Clockwise)

Preceding gene: 209549416

Following gene: 209549418

Centisome position: 41.21

GC content: 64.06

Gene sequence:

>498_bases
ATGAGCGGCGGAAAGCCCGGCCTCACGCATATCGATGCCTCCGGCGAGGCGCATATGGTCGATGTCTCCGACAAGGCCGA
GACGGTGCGCATCGCCACGGCAGAGGGCCATGTGAAAATGGCGGCGGAAACGCTGGCACTGATCCGCCAGGGCAATGCCA
AGAAGGGCGATGTCATCCGCACGGCGCGCCTTGCCGGCATCATGGCGGCAAAACGCACCGCTGATCTCATTCCGCTCTGC
CATCCGCTGATGTTGACCAAGGTCACCGTCGAGATCGAGGAAGATGCCGCCCTGCCGGGCCTGCGCGTCACGGCAACCGC
CAAGCTGACCGGCAAGACCGGTGTGGAGATGGAGGCGCTGACCGCCGTCTCGGTCGCCTGCCTTACCATCTACGACATGG
CCAAGGCCGCCGATAAGGCAATGGAGATCGGCGGCGTCAGGCTGCTCGAAAAATCCGGCGGCAAGTCGGGCGATTTCCGT
CATCCGGAGGCGAGATGA

Upstream 100 bases:

>100_bases
AGCACCTTCCTTGTCGGCGAAAGCCTGATGCGAAAAGACGACGTAACGGCCGCCACCCGCGCGCTGCTCTTCGGCGAAGC
CGCCATCGCGGCCGAATGAT

Downstream 100 bases:

>100_bases
ACCTTCTCCCGGTCGCAGAGGCCTTAAGCCGGCTGCTCTCCCGCGCAACGCCCGTCGCGGCATCCGAGACATTGCCGCTC
GCCGAGGCTGAAGGCCGCGT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSGGKPGLTHIDASGEAHMVDVSDKAETVRIATAEGHVKMAAETLALIRQGNAKKGDVIRTARLAGIMAAKRTADLIPLC
HPLMLTKVTVEIEEDAALPGLRVTATAKLTGKTGVEMEALTAVSVACLTIYDMAKAADKAMEIGGVRLLEKSGGKSGDFR
HPEAR

Sequences:

>Translated_165_residues
MSGGKPGLTHIDASGEAHMVDVSDKAETVRIATAEGHVKMAAETLALIRQGNAKKGDVIRTARLAGIMAAKRTADLIPLC
HPLMLTKVTVEIEEDAALPGLRVTATAKLTGKTGVEMEALTAVSVACLTIYDMAKAADKAMEIGGVRLLEKSGGKSGDFR
HPEAR
>Mature_164_residues
SGGKPGLTHIDASGEAHMVDVSDKAETVRIATAEGHVKMAAETLALIRQGNAKKGDVIRTARLAGIMAAKRTADLIPLCH
PLMLTKVTVEIEEDAALPGLRVTATAKLTGKTGVEMEALTAVSVACLTIYDMAKAADKAMEIGGVRLLEKSGGKSGDFRH
PEAR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=67.3202614379085, Blast_Score=195, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=45.6375838926174, Blast_Score=133, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=50.6329113924051, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=51.0344827586207, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17259; Mature: 17128

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGKPGLTHIDASGEAHMVDVSDKAETVRIATAEGHVKMAAETLALIRQGNAKKGDVIR
CCCCCCCCEEEECCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHH
TARLAGIMAAKRTADLIPLCHPLMLTKVTVEIEEDAALPGLRVTATAKLTGKTGVEMEAL
HHHHHHHHHHHHHHCHHHHHHHHEEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHH
TAVSVACLTIYDMAKAADKAMEIGGVRLLEKSGGKSGDFRHPEAR
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGGKPGLTHIDASGEAHMVDVSDKAETVRIATAEGHVKMAAETLALIRQGNAKKGDVIR
CCCCCCCEEEECCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHH
TARLAGIMAAKRTADLIPLCHPLMLTKVTVEIEEDAALPGLRVTATAKLTGKTGVEMEAL
HHHHHHHHHHHHHHCHHHHHHHHEEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHH
TAVSVACLTIYDMAKAADKAMEIGGVRLLEKSGGKSGDFRHPEAR
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]