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The map label for this gene is pah [H]

Identifier: 209549372

GI number: 209549372

Start: 1820640

End: 1821551

Strand: Direct

Name: pah [H]

Synonym: Rleg2_1777

Alternate gene names: 209549372

Gene position: 1820640-1821551 (Clockwise)

Preceding gene: 209549370

Following gene: 209549374

Centisome position: 40.12

GC content: 65.57

Gene sequence:

>912_bases
ATGACCACCTCGCCCTCCTTTCTCGGCCTTCCCAATCGCCTCGCTGATGACCGGTTGCCCCGCGCGGTGATTTTCGCGGC
CGCTCATGGCACCACCTATCCCGGCAAGGACGGCAGCGGCTATGCCTTGGCGGCCGGCGCCATCCGTTCTGCAAGCCAGG
ACGATGCCGGTCTCATCGAGCACTGGGATTTCGATCTCGGCGGTCCGCTGTTCGACGGCAAGCCGATCTCATGCATCGAC
GCCGGCGATGTCGAGACCGCCATGCGCGACAATATCGGCAACCGGGCGCGGATCGAGGCGAAGACGCGCGAGGTATTGGC
ACTGCCGGCCATACCGATCCTGCTCGGCGGCGACTGTTCCGTGACCATTCCTTTCCTTGCCGGCTTTGCGGCGCAAGGGC
CGGTCTGGGTCCTGCAGATCGACGCCCATATCGATTGGCGCGACGAGGTGCATGGCGAACATCACGGCTATTCCAGTCCG
ATGCGCCGGGCGAGCGAGATGTCGCATGTCGCCGGCATGGTGCAGGTCGGCCTGCGCAGCGTCGGCAGCGCGCGCACCGC
CGACATCGAAGCGGCGCAACGCTATGGTAGCTGTTTTGTCACCGCTCGCGAGGTTCATAGCCAGGGCGTCGGCGCCGCCC
TCCAGCATATCCCGGAAGGAGCGCAGGTCGTCGTCACCCTTGATTGCGACAGCATCGATCCCGGCATCATGCCCGGTGTG
GCGGCGCGGACCCCTGGTGGCCTCACCTACACTGAAGTGATCGACCTGATTGCGGGCCTCGGCAGGCGGGCGAGGATCGC
AGGATTCGACCTTGTCGAGTTCTATCCTCCTGCCGACATCGACGGCCTGTCGGCGCTCACCGCCTCGCGGCTTCTCGTCA
ATGCGATCGGCGCCATCGTCCGGCAGGCTTGA

Upstream 100 bases:

>100_bases
GCGGGATATGGCGAGCGGCGTAATTAAGCTCTCCCAAAAAGTTCTCAAAAATTTCCAAAGGCGCTAAACAGGTCAGGATC
GAACGCAGGACCATCAGGAA

Downstream 100 bases:

>100_bases
TCCTGCTTCTCGCAGCAAGCCGTCCACGGGGTGATTGCGCTTTTTCTCCTAGGCAACTTTGCCCAGACGTGGCTCCGTCC
CAGCCAGAAGCCGCTGAAAG

Product: arginase/agmatinase/formiminoglutamase

Products: NA

Alternate protein names: Proclavaminic acid amidino hydrolase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTTSPSFLGLPNRLADDRLPRAVIFAAAHGTTYPGKDGSGYALAAGAIRSASQDDAGLIEHWDFDLGGPLFDGKPISCID
AGDVETAMRDNIGNRARIEAKTREVLALPAIPILLGGDCSVTIPFLAGFAAQGPVWVLQIDAHIDWRDEVHGEHHGYSSP
MRRASEMSHVAGMVQVGLRSVGSARTADIEAAQRYGSCFVTAREVHSQGVGAALQHIPEGAQVVVTLDCDSIDPGIMPGV
AARTPGGLTYTEVIDLIAGLGRRARIAGFDLVEFYPPADIDGLSALTASRLLVNAIGAIVRQA

Sequences:

>Translated_303_residues
MTTSPSFLGLPNRLADDRLPRAVIFAAAHGTTYPGKDGSGYALAAGAIRSASQDDAGLIEHWDFDLGGPLFDGKPISCID
AGDVETAMRDNIGNRARIEAKTREVLALPAIPILLGGDCSVTIPFLAGFAAQGPVWVLQIDAHIDWRDEVHGEHHGYSSP
MRRASEMSHVAGMVQVGLRSVGSARTADIEAAQRYGSCFVTAREVHSQGVGAALQHIPEGAQVVVTLDCDSIDPGIMPGV
AARTPGGLTYTEVIDLIAGLGRRARIAGFDLVEFYPPADIDGLSALTASRLLVNAIGAIVRQA
>Mature_302_residues
TTSPSFLGLPNRLADDRLPRAVIFAAAHGTTYPGKDGSGYALAAGAIRSASQDDAGLIEHWDFDLGGPLFDGKPISCIDA
GDVETAMRDNIGNRARIEAKTREVLALPAIPILLGGDCSVTIPFLAGFAAQGPVWVLQIDAHIDWRDEVHGEHHGYSSPM
RRASEMSHVAGMVQVGLRSVGSARTADIEAAQRYGSCFVTAREVHSQGVGAALQHIPEGAQVVVTLDCDSIDPGIMPGVA
ARTPGGLTYTEVIDLIAGLGRRARIAGFDLVEFYPPADIDGLSALTASRLLVNAIGAIVRQA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=229, Percent_Identity=30.5676855895196, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1789306, Length=244, Percent_Identity=28.6885245901639, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.22 [H]

Molecular weight: Translated: 31843; Mature: 31712

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSPSFLGLPNRLADDRLPRAVIFAAAHGTTYPGKDGSGYALAAGAIRSASQDDAGLIE
CCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCE
HWDFDLGGPLFDGKPISCIDAGDVETAMRDNIGNRARIEAKTREVLALPAIPILLGGDCS
ECCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCEEEEHHHHHEEECCCEEEEECCCCC
VTIPFLAGFAAQGPVWVLQIDAHIDWRDEVHGEHHGYSSPMRRASEMSHVAGMVQVGLRS
EEHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGSARTADIEAAQRYGSCFVTAREVHSQGVGAALQHIPEGAQVVVTLDCDSIDPGIMPGV
CCCCCHHHHHHHHHHCCEEEEHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCC
AARTPGGLTYTEVIDLIAGLGRRARIAGFDLVEFYPPADIDGLSALTASRLLVNAIGAIV
CCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHH
RQA
HCC
>Mature Secondary Structure 
TTSPSFLGLPNRLADDRLPRAVIFAAAHGTTYPGKDGSGYALAAGAIRSASQDDAGLIE
CCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCE
HWDFDLGGPLFDGKPISCIDAGDVETAMRDNIGNRARIEAKTREVLALPAIPILLGGDCS
ECCCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCEEEEHHHHHEEECCCEEEEECCCCC
VTIPFLAGFAAQGPVWVLQIDAHIDWRDEVHGEHHGYSSPMRRASEMSHVAGMVQVGLRS
EEHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGSARTADIEAAQRYGSCFVTAREVHSQGVGAALQHIPEGAQVVVTLDCDSIDPGIMPGV
CCCCCHHHHHHHHHHCCEEEEHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCC
AARTPGGLTYTEVIDLIAGLGRRARIAGFDLVEFYPPADIDGLSALTASRLLVNAIGAIV
CCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHH
RQA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8088547 [H]