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The map label for this gene is yybE [H]

Identifier: 209549276

GI number: 209549276

Start: 1709109

End: 1710059

Strand: Direct

Name: yybE [H]

Synonym: Rleg2_1679

Alternate gene names: 209549276

Gene position: 1709109-1710059 (Clockwise)

Preceding gene: 209549268

Following gene: 209549278

Centisome position: 37.66

GC content: 63.72

Gene sequence:

>951_bases
ATGCTGCACTCCAGAAAGCTTCTCTATATCAACGAGATCGCCCGCTCGGGTTCGATCCGTAAGGCGGCAGCGCGCTTGAA
CGTCGCCTCGTCTGCGATCAACCGGCAGATATTGGCGCTGGAGGCGGAGATGGGGGCGCCGCTTTTCGAACGCCTGCCGC
GCGGCCTGCGCCTGACGGCGGCCGGCGAGCTCTGCATCGAACATATTCGCGAGGTGCTGAAGAACTACGAGCGGCTGGAG
GGCCGCATCCGCAGCCTGAAGATGCAGCAGGCCGGCAAGGTCCGTATCGTCACCACGGTTGGGCTTGCCGCCGGGCCGCT
GCCTGACATCGTTTCCCGCTTCCAGTCGGAGCATCCGCGGGTCTTCATGCAACTGCGCAACGATGCCGGCACGATGACCG
TCAATCCGGTACTTTCGGGAGAAGTGGATATCGGCCTCGGCTTCAATATTCCGGCCACACCCGGTATCCGCGCGCTCGGC
AGTTTCGACATCCCGATCGGCGTCGTCCTGCCGCCCGGCCATCATCTGATCGGGCCGGGTCCGATCAACCTTGCCGACAT
CGTCCAGGAACGCCTGGTGCTGGCCCAGCAGGGCACCAGCCTGCGTGACGTGATCAATCTGGCCCTGGCGCGGCTCGACG
TGCATGTCGAGCCGGTGCTTGAAACCAATGCCTCGGAGATGTTGAAGAAGCTGGTCAAGTCGGGGGCGGGGCTGACGATC
CTCAACCCGCTCGACGTCATCACTGAGTGCCGGCAGGGCGAATTGGTCTTCCGGCCGATCGCCGAGCCGCATGCGCGCCA
CCAGCCGATGAAGCTTTTTGCCCGCGCCCGTGCGCCGCTCGATTCCGCCACCAGCCTGTTCGTCGAATATCTGCTCGCCG
AACTTGCTGGCCTCGTGCAGGAACTGCAGGCCAAAGGCCATATCGCGATGGAAAAGCCTGTTGCCCCTTAG

Upstream 100 bases:

>100_bases
AAGCATCAAATTTCGTGCGCAATGATGCCTTTTTGGCATCTCAGCAACGGCCTGTTCCAAATTTGCGCTGACTGCTTCAA
TTTTATGCAACGAGGTTGCG

Downstream 100 bases:

>100_bases
AACAGGATGTTTTCCGAAAACCGCTCACACTCTTCGGCATCATGCTCCAGGTGCTTTCGCCGGCGCTATCGTGAATAGAG
GTTGGAAAGCGGATAGCGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLHSRKLLYINEIARSGSIRKAAARLNVASSAINRQILALEAEMGAPLFERLPRGLRLTAAGELCIEHIREVLKNYERLE
GRIRSLKMQQAGKVRIVTTVGLAAGPLPDIVSRFQSEHPRVFMQLRNDAGTMTVNPVLSGEVDIGLGFNIPATPGIRALG
SFDIPIGVVLPPGHHLIGPGPINLADIVQERLVLAQQGTSLRDVINLALARLDVHVEPVLETNASEMLKKLVKSGAGLTI
LNPLDVITECRQGELVFRPIAEPHARHQPMKLFARARAPLDSATSLFVEYLLAELAGLVQELQAKGHIAMEKPVAP

Sequences:

>Translated_316_residues
MLHSRKLLYINEIARSGSIRKAAARLNVASSAINRQILALEAEMGAPLFERLPRGLRLTAAGELCIEHIREVLKNYERLE
GRIRSLKMQQAGKVRIVTTVGLAAGPLPDIVSRFQSEHPRVFMQLRNDAGTMTVNPVLSGEVDIGLGFNIPATPGIRALG
SFDIPIGVVLPPGHHLIGPGPINLADIVQERLVLAQQGTSLRDVINLALARLDVHVEPVLETNASEMLKKLVKSGAGLTI
LNPLDVITECRQGELVFRPIAEPHARHQPMKLFARARAPLDSATSLFVEYLLAELAGLVQELQAKGHIAMEKPVAP
>Mature_316_residues
MLHSRKLLYINEIARSGSIRKAAARLNVASSAINRQILALEAEMGAPLFERLPRGLRLTAAGELCIEHIREVLKNYERLE
GRIRSLKMQQAGKVRIVTTVGLAAGPLPDIVSRFQSEHPRVFMQLRNDAGTMTVNPVLSGEVDIGLGFNIPATPGIRALG
SFDIPIGVVLPPGHHLIGPGPINLADIVQERLVLAQQGTSLRDVINLALARLDVHVEPVLETNASEMLKKLVKSGAGLTI
LNPLDVITECRQGELVFRPIAEPHARHQPMKLFARARAPLDSATSLFVEYLLAELAGLVQELQAKGHIAMEKPVAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=266, Percent_Identity=29.6992481203008, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI157672245, Length=246, Percent_Identity=25.2032520325203, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790399, Length=301, Percent_Identity=26.2458471760797, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787601, Length=174, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788887, Length=259, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082132, Length=263, Percent_Identity=22.8136882129278, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786401, Length=256, Percent_Identity=25.390625, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367136, Length=257, Percent_Identity=24.124513618677, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787530, Length=295, Percent_Identity=22.0338983050847, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=286, Percent_Identity=22.3776223776224, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=301, Percent_Identity=22.2591362126246, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=24.0677966101695, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693105, Length=280, Percent_Identity=22.5, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=264, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=26.6129032258064, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788296, Length=245, Percent_Identity=26.9387755102041, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081904, Length=290, Percent_Identity=23.7931034482759, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34364; Mature: 34364

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHSRKLLYINEIARSGSIRKAAARLNVASSAINRQILALEAEMGAPLFERLPRGLRLTA
CCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHEEEEHHHCCHHHHHCCCCEEEEH
AGELCIEHIREVLKNYERLEGRIRSLKMQQAGKVRIVTTVGLAAGPLPDIVSRFQSEHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
VFMQLRNDAGTMTVNPVLSGEVDIGLGFNIPATPGIRALGSFDIPIGVVLPPGHHLIGPG
EEEEECCCCCCEEECCEECCCEEEECCCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCC
PINLADIVQERLVLAQQGTSLRDVINLALARLDVHVEPVLETNASEMLKKLVKSGAGLTI
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEECHHHCCCHHHHHHHHHHCCCCEEE
LNPLDVITECRQGELVFRPIAEPHARHQPMKLFARARAPLDSATSLFVEYLLAELAGLVQ
ECHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ELQAKGHIAMEKPVAP
HHHHCCCEECCCCCCC
>Mature Secondary Structure
MLHSRKLLYINEIARSGSIRKAAARLNVASSAINRQILALEAEMGAPLFERLPRGLRLTA
CCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHEEEEHHHCCHHHHHCCCCEEEEH
AGELCIEHIREVLKNYERLEGRIRSLKMQQAGKVRIVTTVGLAAGPLPDIVSRFQSEHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
VFMQLRNDAGTMTVNPVLSGEVDIGLGFNIPATPGIRALGSFDIPIGVVLPPGHHLIGPG
EEEEECCCCCCEEECCEECCCEEEECCCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCC
PINLADIVQERLVLAQQGTSLRDVINLALARLDVHVEPVLETNASEMLKKLVKSGAGLTI
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEECHHHCCCHHHHHHHHHHCCCCEEE
LNPLDVITECRQGELVFRPIAEPHARHQPMKLFARARAPLDSATSLFVEYLLAELAGLVQ
ECHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ELQAKGHIAMEKPVAP
HHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]