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The map label for this gene is ntrY [H]

Identifier: 209549228

GI number: 209549228

Start: 1657916

End: 1660186

Strand: Direct

Name: ntrY [H]

Synonym: Rleg2_1629

Alternate gene names: 209549228

Gene position: 1657916-1660186 (Clockwise)

Preceding gene: 209549227

Following gene: 209549229

Centisome position: 36.53

GC content: 65.21

Gene sequence:

>2271_bases
ATGACGCAGGATGGGGTATCGCCGGCGGCGGCGGGCGAGGCGGTGACCACGGTGACCGATCGCCGCGCCCTTTTCGCCGT
GCCCGGCCTGGTGCTCGCCGGTGGAGCGCTTCTCTGCGCCACGGCGACACTGTTTGTGCTGCTCGGCCTCACGCCGATCG
CGCCGACGTCGCATGTCGTCATCACCTCGGTCATCGTCAATTCCTTCTTCGTCCTGACGCTGCTGGCGCTGATCGCCCGT
GAGGTGGCAAGGCTGCTCAAGGCGCGTACCCGCGGCCGGGCGGCTGCACGCCTGCATATCCGCATCGTCGTGCTCTTCTC
GATCGTCGCGATCACGCCGGCGATCCTCGTCGCCATCTTTGCCAGCATCACGCTGAATGCCGGCCTCGATCGCTGGTTTG
CGTTGCGCACCCAGTCGATCGTCAGCTCGTCGCGCAACATCGGCCAAGCCTATATGATGGAAAACGCCAGCTACCTGCAG
GGGCAGACGGTTTCCATGGCCAACGACCTGGAGCGCAACCGCGCGCTCTACAGCCTCGACAGGACGGGCTTTGCCGACCT
GATGACGCGCCAGGCGAGGGGGCGCGGCCTGCTCGGCTCCTTCCTCGTCGAGCGCGACGGTTCGGTGATCGTCCAGGCCG
ACATCACCACCGAAAAGCCGTTGCCGGCAATCCCGCAGGACGCGCTGGAGAAGGCCGCGGCCGGCCAGCCGACGCTCATT
CCGCCTGGCGTCACCAACCTCGTCGGCGCCATCATCAAGCTCGATGCCATCCAGGGCACCTTCCTCTATACGGTGCGCGC
CGTCGATCCGAAGGTCATGGGCGCCATGCGGATGATGGAAGAGAACGCCACCGAATATCGCTCGATGGAAGCCAACCGCT
TCTCGCTGCAGATCGCGTTCGCCGTGCTCTATATCGGCTTCGCGCTGATCGTGCTGCTCGCGGCGATCTGGACGGCGATC
GCGGTGGCCGACCGCATCGTCCGGCCGATCCGGCTCCTGATCACCGCGGCCGACAGCGTGGCGTCGGGCAATATGGATAT
CGTCGTGCCGGTGCACGCCGTCGATGGCGACGTCGCCAATCTGTCGCGTACCTTCAACAAGATGATTTCGGAAATCCGCA
CCCAGCGCGACGAGATCCTCGAAGCCAAGGACGAGGTCGACGACCGCCGCCGCTTCATCGAGGCGGTGCTGTCGGGCGTC
ACCGCAGCGGTCATCGGCGTCGAGCAGGACCGCCGCATCGCCATCGTCAACAGTTCGGCCGAGACGCTGATGTCGCTGTC
GGCCGATGAGATGCTCGGCAAGCAGCTGGCCGAGATCGCGCCTGAGGTCGATCACGTGCTGACCGAGGCGGCGTCGCGGC
ATCGCGGCGATTTCCGCAAGCAGATCGCGCTCGTGCGCGGCGGCACCGTGCGGACGCTGAGCGTGCAGGTCACCCGCGAG
GAAGTGCGCGATATGAGCGAATCCTATGTGATCACGCTCGACGACATCACCGACCTCGTCATCGCCCAGCGCTCGACCGC
CTGGGGTGACGTCGCACGGCGCATCGCCCATGAGATCAAGAACCCGCTGACCCCGATCCAGCTTTCCGCCGAGCGCATTC
AGCGCCGCTACGGCAAGCAGATCGATCCGGGCGATCGGACCGTCTTCGACCAGTGCACGGATACGATCATCCGCCAGGTC
GGCGATATCGGTCGCATGGTCGACGAATTCTCCGCCTTCGCCCGCATGCCGAAGCCGACCAAGGAGCCGAGCGACCTGCG
CGAGATCCTGCGCGACGCGATCTTCCTGCGCGAGATGGGCAACAACCACGTCACCTTCGGGCAGGATTTCGGCGACCAGC
CGCTGGAGGGCCTGTTCGACAGCCGCATGCTCGGCCAGGCTTTCGGAAATCTGATCAAGAATGCCGTGGAGGCAATCGAG
GCCGTTCCGAGCGACGAACGGGACGAACGCAAGATTCTCGTTCGCGCCGCCCTCGATGCCGCCCGCGACCGCTTCACCGT
CGATGTCATCGACAATGGCCGCGGCCTGCCGGTGGAGAACCGCCACAGCATTCTGGAACCCTATATGACGATGCGCGAGA
AGGGCACCGGCCTCGGTCTCGCCATCGTCAAGAAGATCATCGAAGAACATGGCGGGCAGCTCGAGCTGCATGATGCGCCC
GCCGATTTTGACCGGGGAAGAGGGGCCATGATCCGCGTGCATCTGCCACGCCGGGATCCGACGCCCACCTCTCCCGCAGC
CAATGACAAGGAAAGCGTTTATGGCCTCTGA

Upstream 100 bases:

>100_bases
GCTCCCGATCGAGTCGTTCCAGCGCTGGCTTTCTTGAGCCGGCGTTCTTTGGGTTCGATCGGATGGCGCGGGCGGCGGGT
GCCGTCTGAAGAGAGGCCGA

Downstream 100 bases:

>100_bases
TATTCTCGTCGTCGACGACGAGCACGATATTCGCGAGATCGTTTCCGGCATTCTCTCCGACGAGGGACACGAAACGCGCA
CGGCCCATGACAGCGACAGT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MTQDGVSPAAAGEAVTTVTDRRALFAVPGLVLAGGALLCATATLFVLLGLTPIAPTSHVVITSVIVNSFFVLTLLALIAR
EVARLLKARTRGRAAARLHIRIVVLFSIVAITPAILVAIFASITLNAGLDRWFALRTQSIVSSSRNIGQAYMMENASYLQ
GQTVSMANDLERNRALYSLDRTGFADLMTRQARGRGLLGSFLVERDGSVIVQADITTEKPLPAIPQDALEKAAAGQPTLI
PPGVTNLVGAIIKLDAIQGTFLYTVRAVDPKVMGAMRMMEENATEYRSMEANRFSLQIAFAVLYIGFALIVLLAAIWTAI
AVADRIVRPIRLLITAADSVASGNMDIVVPVHAVDGDVANLSRTFNKMISEIRTQRDEILEAKDEVDDRRRFIEAVLSGV
TAAVIGVEQDRRIAIVNSSAETLMSLSADEMLGKQLAEIAPEVDHVLTEAASRHRGDFRKQIALVRGGTVRTLSVQVTRE
EVRDMSESYVITLDDITDLVIAQRSTAWGDVARRIAHEIKNPLTPIQLSAERIQRRYGKQIDPGDRTVFDQCTDTIIRQV
GDIGRMVDEFSAFARMPKPTKEPSDLREILRDAIFLREMGNNHVTFGQDFGDQPLEGLFDSRMLGQAFGNLIKNAVEAIE
AVPSDERDERKILVRAALDAARDRFTVDVIDNGRGLPVENRHSILEPYMTMREKGTGLGLAIVKKIIEEHGGQLELHDAP
ADFDRGRGAMIRVHLPRRDPTPTSPAANDKESVYGL

Sequences:

>Translated_756_residues
MTQDGVSPAAAGEAVTTVTDRRALFAVPGLVLAGGALLCATATLFVLLGLTPIAPTSHVVITSVIVNSFFVLTLLALIAR
EVARLLKARTRGRAAARLHIRIVVLFSIVAITPAILVAIFASITLNAGLDRWFALRTQSIVSSSRNIGQAYMMENASYLQ
GQTVSMANDLERNRALYSLDRTGFADLMTRQARGRGLLGSFLVERDGSVIVQADITTEKPLPAIPQDALEKAAAGQPTLI
PPGVTNLVGAIIKLDAIQGTFLYTVRAVDPKVMGAMRMMEENATEYRSMEANRFSLQIAFAVLYIGFALIVLLAAIWTAI
AVADRIVRPIRLLITAADSVASGNMDIVVPVHAVDGDVANLSRTFNKMISEIRTQRDEILEAKDEVDDRRRFIEAVLSGV
TAAVIGVEQDRRIAIVNSSAETLMSLSADEMLGKQLAEIAPEVDHVLTEAASRHRGDFRKQIALVRGGTVRTLSVQVTRE
EVRDMSESYVITLDDITDLVIAQRSTAWGDVARRIAHEIKNPLTPIQLSAERIQRRYGKQIDPGDRTVFDQCTDTIIRQV
GDIGRMVDEFSAFARMPKPTKEPSDLREILRDAIFLREMGNNHVTFGQDFGDQPLEGLFDSRMLGQAFGNLIKNAVEAIE
AVPSDERDERKILVRAALDAARDRFTVDVIDNGRGLPVENRHSILEPYMTMREKGTGLGLAIVKKIIEEHGGQLELHDAP
ADFDRGRGAMIRVHLPRRDPTPTSPAANDKESVYGL
>Mature_755_residues
TQDGVSPAAAGEAVTTVTDRRALFAVPGLVLAGGALLCATATLFVLLGLTPIAPTSHVVITSVIVNSFFVLTLLALIARE
VARLLKARTRGRAAARLHIRIVVLFSIVAITPAILVAIFASITLNAGLDRWFALRTQSIVSSSRNIGQAYMMENASYLQG
QTVSMANDLERNRALYSLDRTGFADLMTRQARGRGLLGSFLVERDGSVIVQADITTEKPLPAIPQDALEKAAAGQPTLIP
PGVTNLVGAIIKLDAIQGTFLYTVRAVDPKVMGAMRMMEENATEYRSMEANRFSLQIAFAVLYIGFALIVLLAAIWTAIA
VADRIVRPIRLLITAADSVASGNMDIVVPVHAVDGDVANLSRTFNKMISEIRTQRDEILEAKDEVDDRRRFIEAVLSGVT
AAVIGVEQDRRIAIVNSSAETLMSLSADEMLGKQLAEIAPEVDHVLTEAASRHRGDFRKQIALVRGGTVRTLSVQVTREE
VRDMSESYVITLDDITDLVIAQRSTAWGDVARRIAHEIKNPLTPIQLSAERIQRRYGKQIDPGDRTVFDQCTDTIIRQVG
DIGRMVDEFSAFARMPKPTKEPSDLREILRDAIFLREMGNNHVTFGQDFGDQPLEGLFDSRMLGQAFGNLIKNAVEAIEA
VPSDERDERKILVRAALDAARDRFTVDVIDNGRGLPVENRHSILEPYMTMREKGTGLGLAIVKKIIEEHGGQLELHDAPA
DFDRGRGAMIRVHLPRRDPTPTSPAANDKESVYGL

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=495, Percent_Identity=19.7979797979798, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790300, Length=357, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=212, Percent_Identity=29.7169811320755, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82677; Mature: 82546

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDGVSPAAAGEAVTTVTDRRALFAVPGLVLAGGALLCATATLFVLLGLTPIAPTSHVV
CCCCCCCCHHCCCHHHHHHCCHHHHHCCHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHH
ITSVIVNSFFVLTLLALIAREVARLLKARTRGRAAARLHIRIVVLFSIVAITPAILVAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASITLNAGLDRWFALRTQSIVSSSRNIGQAYMMENASYLQGQTVSMANDLERNRALYSLD
HHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCHHHHHHHHHHCCHHHHHC
RTGFADLMTRQARGRGLLGSFLVERDGSVIVQADITTEKPLPAIPQDALEKAAAGQPTLI
CCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCC
PPGVTNLVGAIIKLDAIQGTFLYTVRAVDPKVMGAMRMMEENATEYRSMEANRFSLQIAF
CCCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVLYIGFALIVLLAAIWTAIAVADRIVRPIRLLITAADSVASGNMDIVVPVHAVDGDVAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
LSRTFNKMISEIRTQRDEILEAKDEVDDRRRFIEAVLSGVTAAVIGVEQDRRIAIVNSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCH
ETLMSLSADEMLGKQLAEIAPEVDHVLTEAASRHRGDFRKQIALVRGGTVRTLSVQVTRE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEEEHH
EVRDMSESYVITLDDITDLVIAQRSTAWGDVARRIAHEIKNPLTPIQLSAERIQRRYGKQ
HHHCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
IDPGDRTVFDQCTDTIIRQVGDIGRMVDEFSAFARMPKPTKEPSDLREILRDAIFLREMG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
NNHVTFGQDFGDQPLEGLFDSRMLGQAFGNLIKNAVEAIEAVPSDERDERKILVRAALDA
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ARDRFTVDVIDNGRGLPVENRHSILEPYMTMREKGTGLGLAIVKKIIEEHGGQLELHDAP
HCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCC
ADFDRGRGAMIRVHLPRRDPTPTSPAANDKESVYGL
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
TQDGVSPAAAGEAVTTVTDRRALFAVPGLVLAGGALLCATATLFVLLGLTPIAPTSHVV
CCCCCCCHHCCCHHHHHHCCHHHHHCCHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHH
ITSVIVNSFFVLTLLALIAREVARLLKARTRGRAAARLHIRIVVLFSIVAITPAILVAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASITLNAGLDRWFALRTQSIVSSSRNIGQAYMMENASYLQGQTVSMANDLERNRALYSLD
HHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCHHHHHHHHHHCCHHHHHC
RTGFADLMTRQARGRGLLGSFLVERDGSVIVQADITTEKPLPAIPQDALEKAAAGQPTLI
CCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCC
PPGVTNLVGAIIKLDAIQGTFLYTVRAVDPKVMGAMRMMEENATEYRSMEANRFSLQIAF
CCCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVLYIGFALIVLLAAIWTAIAVADRIVRPIRLLITAADSVASGNMDIVVPVHAVDGDVAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
LSRTFNKMISEIRTQRDEILEAKDEVDDRRRFIEAVLSGVTAAVIGVEQDRRIAIVNSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCH
ETLMSLSADEMLGKQLAEIAPEVDHVLTEAASRHRGDFRKQIALVRGGTVRTLSVQVTRE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEEEHH
EVRDMSESYVITLDDITDLVIAQRSTAWGDVARRIAHEIKNPLTPIQLSAERIQRRYGKQ
HHHCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
IDPGDRTVFDQCTDTIIRQVGDIGRMVDEFSAFARMPKPTKEPSDLREILRDAIFLREMG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
NNHVTFGQDFGDQPLEGLFDSRMLGQAFGNLIKNAVEAIEAVPSDERDERKILVRAALDA
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ARDRFTVDVIDNGRGLPVENRHSILEPYMTMREKGTGLGLAIVKKIIEEHGGQLELHDAP
HCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCC
ADFDRGRGAMIRVHLPRRDPTPTSPAANDKESVYGL
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]