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The map label for this gene is aatC [H]

Identifier: 209549143

GI number: 209549143

Start: 1568715

End: 1569932

Strand: Direct

Name: aatC [H]

Synonym: Rleg2_1544

Alternate gene names: 209549143

Gene position: 1568715-1569932 (Clockwise)

Preceding gene: 209549142

Following gene: 209549144

Centisome position: 34.57

GC content: 62.64

Gene sequence:

>1218_bases
ATGGAAGAGTTTCACAAAGTCCGGCGTTTGCCGCCTTATGTTTTCGAACAGGTCAACCGTTTGAAAGCAAGCGCGCGAGC
GGGCGGCGCCGATATCATCGATCTCGGCATGGGAAACCCCGACCTTCCCACTCCCCAGTCGATCGTCGACAAGCTGTGCG
AGGTCGTGCAGGATCCGCGCACCCACCGCTATTCCTCCTCCAAGGGCATTCCGGGGCTGCGCCGCGCCCAGGCCGCCTAT
TATGCCCGCCGTTTCGGCGTCAAGCTCAACCCGGATACCCAGGTGGTCGCCACCTTGGGCTCCAAGGAAGGCTTCGCCAA
CATGGCGCAGGCGATCACCGCGCCCGGCGATGTCATCCTCTGCCCGAACCCGACCTATCCGATCCACGCCTTCGGCTTCC
TGATGGCGGGCGGCGTGATACGCTCCATGTCGGTGGAGCCGGACGAGAGCTTTTTCCCGCCGCTTGAGCGCGCGGTCCGG
CATTCGATCCCGAAGCCCCTGGCGCTGATCCTCAACTACCCCTCGAATCCGACGGCCCTCGTCGCAACGCTCGATTTCTA
CAAGGACGTCATCGCCTTCGCCAAGAAGCACGACATCATCGTGCTTTCCGACCTTGCCTATTCGGAGATCTATTTCGACG
GCGCACCGCCGCCCTCGGTTCTCGAAGTGCCGGGTGCAATCGATGTGACGGTCGAGTTCACCTCGATGTCGAAGACCTTC
TCCATGCCCGGCTGGCGTATGGGCTTTGCCGTCGGCAACGAGCGGCTGATTGCGGCACTCACCCGCGTCAAGTCCTACCT
CGACTACGGCGCCTTCACGCCGATCCAGGTGGCGGCGACGCATGCGCTGAACGGCGACGGCTCCGACATTGCTGAAGTCC
GCAACGTCTACAAGCGCCGCCGCGACGTTATGGTCGAAAGCTTCGGCAAGGCCGGCTTCGACGTGCCGCCGCCGGCTGCG
ACCATGTTCGCCTGGGCGAAGATCCCGGAAAAGTTCCGTCATCTCGGTTCGCTTGAGTTTTCCAAGCTGCTGGTCGAGAA
GGCCGACGTCGCCGTTGCCCCGGGCATCGGCTTCGGCGAGCAGGGCGACGACTACGTCCGTCTGGCGCTGGTCGAGAACG
AACACCGCATCCGCCAGGCTGCGCGCAACATCAAGAAGTTCATGTCGACGGCAGACGAAACGATGCACAACGTCATTTCG
CTGAACGCGCACCGTTAA

Upstream 100 bases:

>100_bases
ATGAATACGGCGTTGCGATTCTGAAGTTCGTGTCGCAGCCGCCGGGAGACGGAACGAACTTCGACTGCGGCCCGAAAGCC
GCCTTTCCATGGGGAATGAA

Downstream 100 bases:

>100_bases
TCCAACTCCTAAGGCAGCCGCGTCCTGCGGCTGCCGCCACACAGACATTCAGGATCGATCCATGGCAGATGCCCTCAAAA
TCGGCATTGCGGGCTTGGGC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MEEFHKVRRLPPYVFEQVNRLKASARAGGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAAY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFLMAGGVIRSMSVEPDESFFPPLERAVR
HSIPKPLALILNYPSNPTALVATLDFYKDVIAFAKKHDIIVLSDLAYSEIYFDGAPPPSVLEVPGAIDVTVEFTSMSKTF
SMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRNVYKRRRDVMVESFGKAGFDVPPPAA
TMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGEQGDDYVRLALVENEHRIRQAARNIKKFMSTADETMHNVIS
LNAHR

Sequences:

>Translated_405_residues
MEEFHKVRRLPPYVFEQVNRLKASARAGGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAAY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFLMAGGVIRSMSVEPDESFFPPLERAVR
HSIPKPLALILNYPSNPTALVATLDFYKDVIAFAKKHDIIVLSDLAYSEIYFDGAPPPSVLEVPGAIDVTVEFTSMSKTF
SMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRNVYKRRRDVMVESFGKAGFDVPPPAA
TMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGEQGDDYVRLALVENEHRIRQAARNIKKFMSTADETMHNVIS
LNAHR
>Mature_405_residues
MEEFHKVRRLPPYVFEQVNRLKASARAGGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAAY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFLMAGGVIRSMSVEPDESFFPPLERAVR
HSIPKPLALILNYPSNPTALVATLDFYKDVIAFAKKHDIIVLSDLAYSEIYFDGAPPPSVLEVPGAIDVTVEFTSMSKTF
SMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRNVYKRRRDVMVESFGKAGFDVPPPAA
TMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGEQGDDYVRLALVENEHRIRQAARNIKKFMSTADETMHNVIS
LNAHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=23.5443037974684, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=23.5443037974684, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=22.5063938618926, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=22.5063938618926, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI169881281, Length=242, Percent_Identity=23.5537190082645, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=52.3560209424084, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=25.5208333333333, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=25, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787710, Length=334, Percent_Identity=24.5508982035928, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=22.6829268292683, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=401, Percent_Identity=24.1895261845387, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=401, Percent_Identity=24.1895261845387, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=22.6315789473684, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=20.9718670076726, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573069, Length=424, Percent_Identity=24.7641509433962, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=424, Percent_Identity=24.7641509433962, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=424, Percent_Identity=24.7641509433962, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=424, Percent_Identity=24.7641509433962, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.6979166666667, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44522; Mature: 44522

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFHKVRRLPPYVFEQVNRLKASARAGGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPR
CCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSKGIPGLRRAQAAYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFLMAGGVIRSMSVEPDESFFPPLERAVRHSIPKPLALILNYPSNPTAL
CCCCCCCHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEE
VATLDFYKDVIAFAKKHDIIVLSDLAYSEIYFDGAPPPSVLEVPGAIDVTVEFTSMSKTF
EEHHHHHHHHHHHHHCCCEEEEECCCEEHEEECCCCCCCCEECCCEEEEEEEEECCCHHH
SMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRNVYKRR
CCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHH
RDVMVESFGKAGFDVPPPAATMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGE
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCC
QGDDYVRLALVENEHRIRQAARNIKKFMSTADETMHNVISLNAHR
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEFHKVRRLPPYVFEQVNRLKASARAGGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPR
CCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSKGIPGLRRAQAAYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFLMAGGVIRSMSVEPDESFFPPLERAVRHSIPKPLALILNYPSNPTAL
CCCCCCCHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEE
VATLDFYKDVIAFAKKHDIIVLSDLAYSEIYFDGAPPPSVLEVPGAIDVTVEFTSMSKTF
EEHHHHHHHHHHHHHCCCEEEEECCCEEHEEECCCCCCCCEECCCEEEEEEEEECCCHHH
SMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRNVYKRR
CCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHH
RDVMVESFGKAGFDVPPPAATMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGE
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCC
QGDDYVRLALVENEHRIRQAARNIKKFMSTADETMHNVISLNAHR
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]