BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome.
Accession	NC_011369
Length	4,537,948

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The map label for this gene is fabG [C]

Identifier: 209549043

GI number: 209549043

Start: 1463935

End: 1464768

Strand: Direct

Name: fabG [C]

Synonym: Rleg2_1440

Alternate gene names: 209549043

Gene position: 1463935-1464768 (Clockwise)

Preceding gene: 209549042

Following gene: 209549049

Centisome position: 32.26

GC content: 62.71

Gene sequence:

>834_bases
ATGCGTGATTTCACCGCCCGTCCCGAAGATGGACTCGTCTGGATCTCGGGTGCGAGTTCCGGCATCGGCCGCGCGCTTGC
GCTGAAGCTTGCCGGCGAAGGATACAAGGTCGCCGTCACCGCCCGAAGCCACGAAAAGCTGGTCGAACTGCAGGCCGAGG
CCAGCGGCCTTGCCGGCAGCATCATCGTTCTCGATGGCGACGTCACTGATGCCGAGGACATGGAGCATATCATGGCCTCC
ATCGAATATGAGCACGGCACACTCGCCATGGCGGTCCTCAATGCCGGCGTCTATTTGCCTGTTCATGCCGAGGACCTGAA
CCGCGCCGATTTCGAAAAGAGTTTTGCCGTCAATCTCTCCGGCGTCGTCAACTGCCTGTTGCCGGCGGTCCGCCATATGA
AGGCCAAAGGGCAGGGACAGATCGCCATCGTCTCCTCCGTCACCGGCTATGGCGGCCTGCCGACGGGCGCTGCCTACGGC
GCCACCAAGGCGGCGCTGATCAATATGGCCGAAAGCCTGAAATTCGATCTCGACAAGATGGGCATCCGCATCCAGCTCAT
CTGCCCGGGCTTCGTCGACACACCGGCGACGCGGAAGAACGCCTTTCCCATGCCGTCCCTGGTGTCGACCGACGAAGCCG
CCCAGCAGATTGCCGCCGGGCTGAAATCGCAGGCCTTCGAGATCTCGTTCCCCAGGCGCTTCACCATGATGCTGAAGCTT
GCGCGCATGCTTCCCTACAGCGCCTATTTCATGGTGGTGAACCGCGTGACCGGCTGGCGCGAGCGGCCGTCATCGGCTGG
TCACCATCCGGCGACACCGCATCCGGCGGAATGA

Upstream 100 bases:

>100_bases
AAAGCAGCCACAATGGTGTGATAGAGCCGTAAATCCGGGAGGCGAAGGGAACTTTCCGGACTTGTTTTCGGTTGGTCAGG
CAGAACCGGAGGAACATGTC

Downstream 100 bases:

>100_bases
TCAGCTGCGCGAGAACACCACTTGGCGCACATCGATATTGCGGGCGCGGAAGCCGGCCTCGCAATAGAACAGATAGAATT
CCCAGAGCCGCTTGAAACGC

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRDFTARPEDGLVWISGASSGIGRALALKLAGEGYKVAVTARSHEKLVELQAEASGLAGSIIVLDGDVTDAEDMEHIMAS
IEYEHGTLAMAVLNAGVYLPVHAEDLNRADFEKSFAVNLSGVVNCLLPAVRHMKAKGQGQIAIVSSVTGYGGLPTGAAYG
ATKAALINMAESLKFDLDKMGIRIQLICPGFVDTPATRKNAFPMPSLVSTDEAAQQIAAGLKSQAFEISFPRRFTMMLKL
ARMLPYSAYFMVVNRVTGWRERPSSAGHHPATPHPAE

Sequences:

>Translated_277_residues
MRDFTARPEDGLVWISGASSGIGRALALKLAGEGYKVAVTARSHEKLVELQAEASGLAGSIIVLDGDVTDAEDMEHIMAS
IEYEHGTLAMAVLNAGVYLPVHAEDLNRADFEKSFAVNLSGVVNCLLPAVRHMKAKGQGQIAIVSSVTGYGGLPTGAAYG
ATKAALINMAESLKFDLDKMGIRIQLICPGFVDTPATRKNAFPMPSLVSTDEAAQQIAAGLKSQAFEISFPRRFTMMLKL
ARMLPYSAYFMVVNRVTGWRERPSSAGHHPATPHPAE
>Mature_277_residues
MRDFTARPEDGLVWISGASSGIGRALALKLAGEGYKVAVTARSHEKLVELQAEASGLAGSIIVLDGDVTDAEDMEHIMAS
IEYEHGTLAMAVLNAGVYLPVHAEDLNRADFEKSFAVNLSGVVNCLLPAVRHMKAKGQGQIAIVSSVTGYGGLPTGAAYG
ATKAALINMAESLKFDLDKMGIRIQLICPGFVDTPATRKNAFPMPSLVSTDEAAQQIAAGLKSQAFEISFPRRFTMMLKL
ARMLPYSAYFMVVNRVTGWRERPSSAGHHPATPHPAE

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI210032110, Length=243, Percent_Identity=26.3374485596708, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI109715829, Length=196, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI142976729, Length=243, Percent_Identity=26.3374485596708, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=35.4838709677419, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=32.5, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=28.7234042553192, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI32483357, Length=190, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=221, Percent_Identity=28.0542986425339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40807363, Length=257, Percent_Identity=26.0700389105058, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI210032112, Length=177, Percent_Identity=27.683615819209, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI150247226, Length=223, Percent_Identity=28.2511210762332, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI223718074, Length=189, Percent_Identity=34.3915343915344, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=202, Percent_Identity=29.2079207920792, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32455239, Length=201, Percent_Identity=32.3383084577114, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=201, Percent_Identity=32.3383084577114, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI50726952, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI5031737, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=28.3653846153846, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI31542939, Length=187, Percent_Identity=28.3422459893048, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4557649, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=33.1578947368421, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=31.7708333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786812, Length=229, Percent_Identity=27.9475982532751, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=29.3478260869565, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=31.3186813186813, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786701, Length=186, Percent_Identity=31.1827956989247, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789378, Length=200, Percent_Identity=29.5, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=34.010152284264, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=225, Percent_Identity=31.5555555555556, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=218, Percent_Identity=33.0275229357798, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=197, Percent_Identity=32.994923857868, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=254, Percent_Identity=27.1653543307087, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=206, Percent_Identity=31.5533980582524, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=208, Percent_Identity=26.4423076923077, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=188, Percent_Identity=29.2553191489362, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=188, Percent_Identity=32.4468085106383, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=194, Percent_Identity=29.3814432989691, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=194, Percent_Identity=29.3814432989691, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=32.1782178217822, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=199, Percent_Identity=31.6582914572864, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=192, Percent_Identity=31.7708333333333, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=186, Percent_Identity=29.5698924731183, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=251, Percent_Identity=23.9043824701195, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=193, Percent_Identity=29.0155440414508, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=30.0925925925926, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=188, Percent_Identity=31.9148936170213, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=227, Percent_Identity=26.8722466960352, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=217, Percent_Identity=26.2672811059908, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=194, Percent_Identity=31.4432989690722, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648944, Length=199, Percent_Identity=28.643216080402, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24580925, Length=191, Percent_Identity=32.4607329842932, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=30.1507537688442, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=250, Percent_Identity=26, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=29.6482412060301, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=186, Percent_Identity=29.5698924731183, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364494, Length=208, Percent_Identity=30.2884615384615, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI23397609, Length=223, Percent_Identity=29.5964125560538, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=187, Percent_Identity=27.807486631016, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24663911, Length=197, Percent_Identity=31.4720812182741, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=209, Percent_Identity=27.7511961722488, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=259, Percent_Identity=25.8687258687259, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221510726, Length=241, Percent_Identity=26.1410788381743, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24665243, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640492, Length=264, Percent_Identity=24.6212121212121, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584752, Length=187, Percent_Identity=29.9465240641711, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=190, Percent_Identity=30.5263157894737, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665247, Length=204, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24581726, Length=259, Percent_Identity=25.4826254826255, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221331216, Length=204, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=32.258064516129, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 29615; Mature: 29615

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFTARPEDGLVWISGASSGIGRALALKLAGEGYKVAVTARSHEKLVELQAEASGLAGS
CCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHHCCCCCEE
IIVLDGDVTDAEDMEHIMASIEYEHGTLAMAVLNAGVYLPVHAEDLNRADFEKSFAVNLS
EEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCEEEEEEHHHCCCHHCCHHHEEEHH
GVVNCLLPAVRHMKAKGQGQIAIVSSVTGYGGLPTGAAYGATKAALINMAESLKFDLDKM
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHC
GIRIQLICPGFVDTPATRKNAFPMPSLVSTDEAAQQIAAGLKSQAFEISFPRRFTMMLKL
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHH
ARMLPYSAYFMVVNRVTGWRERPSSAGHHPATPHPAE
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDFTARPEDGLVWISGASSGIGRALALKLAGEGYKVAVTARSHEKLVELQAEASGLAGS
CCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHHCCCCCEE
IIVLDGDVTDAEDMEHIMASIEYEHGTLAMAVLNAGVYLPVHAEDLNRADFEKSFAVNLS
EEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCEEEEEEHHHCCCHHCCHHHEEEHH
GVVNCLLPAVRHMKAKGQGQIAIVSSVTGYGGLPTGAAYGATKAALINMAESLKFDLDKM
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHC
GIRIQLICPGFVDTPATRKNAFPMPSLVSTDEAAQQIAAGLKSQAFEISFPRRFTMMLKL
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHH
ARMLPYSAYFMVVNRVTGWRERPSSAGHHPATPHPAE
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]