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The map label for this gene is grp [H]

Identifier: 209549007

GI number: 209549007

Start: 1425081

End: 1425542

Strand: Direct

Name: grp [H]

Synonym: Rleg2_1404

Alternate gene names: 209549007

Gene position: 1425081-1425542 (Clockwise)

Preceding gene: 209549005

Following gene: 209549009

Centisome position: 31.4

GC content: 60.17

Gene sequence:

>462_bases
ATGAAAGAAACTGGGAACTTTCGCCGCACCCTTCTGCAGCTCATCCAGGCCGACGGCAGCCTTTCGCTGGCAGATCTGGC
TGAGAAGGCCGGCATGTCGCAGAGCTCGGCCTGGCGGAAGATCCAGGAACTCGAAGCCGACGGCGTCATCCGCAAGCGCG
TGACGCTGCTTGATCCCGGCAAACTCGATCTCAAGCTCTGTGTGATCGCCCATGTCACGCTGGAGGATCACCACGAAGAG
GCGGTCGCCTCCTTCGCTGCGGTGGTGCTGGAGCGGCCGGAGATCATGGAGTGTTACGCCTTGTCGGGCGCCTTCGATTA
TATGCTGAAGATCCGGGCGAGGGACGTCGAAAGCTACGAAGCCTTCATGACGCGGTACCTCATGCGCAACCCGCATGTGC
GCACAGTTGTCTCGAGCTTCGTGCTGCGCGAACTGAAATTCTCGACCGAATTGCCGCTCTGA

Upstream 100 bases:

>100_bases
GACATGGCTGTCATTATCCTCCAGCATTTGCGGATTTTCTTTTCTTTCATCTTGGATCTTGCGATAATGGTGGCAAATTT
TCCCGAATGTGGGGGTGAAA

Downstream 100 bases:

>100_bases
CGCCTGCCGCCGGCGGGGCAGGGATGTTCTTAAATTTATCGCATGCTGTCGCCATGCCGGCTGCCCGGCATGTGCACGGG
AAAGCCCTCGAATGTCTTCA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MKETGNFRRTLLQLIQADGSLSLADLAEKAGMSQSSAWRKIQELEADGVIRKRVTLLDPGKLDLKLCVIAHVTLEDHHEE
AVASFAAVVLERPEIMECYALSGAFDYMLKIRARDVESYEAFMTRYLMRNPHVRTVVSSFVLRELKFSTELPL

Sequences:

>Translated_153_residues
MKETGNFRRTLLQLIQADGSLSLADLAEKAGMSQSSAWRKIQELEADGVIRKRVTLLDPGKLDLKLCVIAHVTLEDHHEE
AVASFAAVVLERPEIMECYALSGAFDYMLKIRARDVESYEAFMTRYLMRNPHVRTVVSSFVLRELKFSTELPL
>Mature_153_residues
MKETGNFRRTLLQLIQADGSLSLADLAEKAGMSQSSAWRKIQELEADGVIRKRVTLLDPGKLDLKLCVIAHVTLEDHHEE
AVASFAAVVLERPEIMECYALSGAFDYMLKIRARDVESYEAFMTRYLMRNPHVRTVVSSFVLRELKFSTELPL

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=145, Percent_Identity=33.7931034482759, Blast_Score=109, Evalue=8e-26,
Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=32, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17358; Mature: 17358

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETGNFRRTLLQLIQADGSLSLADLAEKAGMSQSSAWRKIQELEADGVIRKRVTLLDPG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHEEEECCC
KLDLKLCVIAHVTLEDHHEEAVASFAAVVLERPEIMECYALSGAFDYMLKIRARDVESYE
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHH
AFMTRYLMRNPHVRTVVSSFVLRELKFSTELPL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKETGNFRRTLLQLIQADGSLSLADLAEKAGMSQSSAWRKIQELEADGVIRKRVTLLDPG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHEEEECCC
KLDLKLCVIAHVTLEDHHEEAVASFAAVVLERPEIMECYALSGAFDYMLKIRARDVESYE
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHH
AFMTRYLMRNPHVRTVVSSFVLRELKFSTELPL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]