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The map label for this gene is zraS [C]

Identifier: 209548804

GI number: 209548804

Start: 1210087

End: 1211733

Strand: Direct

Name: zraS [C]

Synonym: Rleg2_1201

Alternate gene names: 209548804

Gene position: 1210087-1211733 (Clockwise)

Preceding gene: 209548802

Following gene: 209548806

Centisome position: 26.67

GC content: 60.23

Gene sequence:

>1647_bases
ATGGATTTGCTGAGTGCCACGGATTGGCTGCGTCACAGGCCGGGTTATACATATCCGCTGGCCGTCGCCTTCGTTGGCCT
GACGTTTCTTCTCAGGCTTGCCGCCAGCGACTATCTCTCCGGCTTTCCCTTTCTGAGCTTCCTCCCGGCGATATTGCTTG
CGAGTTTCATCGGCGGCGCGGGGCCGGGCCTTGTCGCAGCGATACTCGCCGCTTTCATCGTCCAGCAGTTTTTCGTCGAG
CCGCACAATATCTTCTGGCCGGTCAGCGCCGGCCAATGGGTTGGGCTGTCGACCTATCTCATCAATGCGGTGATCATCAT
CGGGCTGATGGAGATGATCATCATCGCGCATCGCCGGCAGAGCCGCCTCCGCAACGAGCTCAACGGTTTCAACACGCGCC
TCGAACAGACGGTGGTCCAGCGCACCGCCGAACTCAGGCACGAGATGGAAGAGAATGCCGCCGCGCAGGCGCAGGTCCGC
CAGCTGCAGAAGATGGAGACGATCGGTCAGCTCACCGGCGGCGTCGCCCATGATTTCAACAATATGCTGGCGATCATCAT
CGGCAACCTCGATCTTGCCCAGCGACGGATGACCGGGCATGAGGATCCCCGCGTGCTGAACTCCATCCAGAATGCCAAAG
ACGGCGCCCAGCGTGCCGCGGTCCTGACCGCGCGTCTGCTCGCTTTCTCGCGCCAGCAGCCGCTCGCCCCTGAGGTCATC
GATCTCAATAAGCTGGTCGGCGGCATGTCCGAGCTGTTGCGGCGTACACTCGGCGAGCAGATCCGGATCGAGACTGTGCT
TGCCGGCGGCCTTTGGCCGAGTTTTGCCGATTTGAGCCAGCTCGAGAACGCTATTCTGAATCTTGCCGTCAACGCCCGCG
ACGCCATGCCCGGCGGCGGACATCTGACCATCGAGACCGCCAATACCGAACTCGACGAGCGCTATTCCCGCATGCATTCG
GAGGTCGATGCCGGCCAATATGTGATGGTCAGCATGACCGACACCGGCACCGGCATGTCGCCTGACGTGATCGAGCGTGC
CTTCGACCCGTTCTACACCACCAAGGGACCCGGCAAGGGCACCGGTCTCGGCCTCAGCCAGGTTTACGGCTACATCAAGC
AAAGCGGCGGCCACATCAAGATCTATTCGGAGATCGACAGGGGCACGACGGTGAAGATCTATTTACCCCGGCATGTCGGC
GCGATGGACGCCAGGTTGAATGCTGCCGGCGCCCAGCCTATTCCCCAAGGCAGCGTCAACGATACGATCCTGGTGGTGGA
AGATGATGAGAACGTCCGCATCATGACCGCCGAAAGCCTGCATGAACTCGGTTACACCGTGTTGCAGGCGGCAAGCGGCA
TGGAGGCGCTTCTGCTTCTGGAAGAAAATCGGGAGGTTGATCTGATCTTCACCGATATCGTCATGCCGCAAATGAGCGGA
CGCCAGCTTGCCGATATCGTCCAGGAAAAATGGCCGGCGATCCGCATCCTCTACACCACGGGTTATACCCGCAACGCCAT
CGTCCATAACGGGGTGCTCGATCATGGCGTCTCCCTGCTTGCCAAGCCCTTCAGCCTGGAGCAGCTCGCCCATAAGATCC
GCGAACTTCTGAATGTGCCGGCGAAAATGGAAAATGAGAGGACGTGA

Upstream 100 bases:

>100_bases
AATCGGAATCGATTTTGGGATAAAACTCTGCAGCAATTCAAAGTGTTACGGCGCTCTCTGCGTGTCTGATAAGGCGCGGC
GCCGTAAGGAGGGGTCTGGA

Downstream 100 bases:

>100_bases
AGCCGCTATGCGGCCGCACGTCCACTGTGTTCTATCGCCTTATTCGATGACCTGGATCACGCGGTGCGTCTTCGGCTCAA
CGATAACGCGCCGCTCATTG

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MDLLSATDWLRHRPGYTYPLAVAFVGLTFLLRLAASDYLSGFPFLSFLPAILLASFIGGAGPGLVAAILAAFIVQQFFVE
PHNIFWPVSAGQWVGLSTYLINAVIIIGLMEMIIIAHRRQSRLRNELNGFNTRLEQTVVQRTAELRHEMEENAAAQAQVR
QLQKMETIGQLTGGVAHDFNNMLAIIIGNLDLAQRRMTGHEDPRVLNSIQNAKDGAQRAAVLTARLLAFSRQQPLAPEVI
DLNKLVGGMSELLRRTLGEQIRIETVLAGGLWPSFADLSQLENAILNLAVNARDAMPGGGHLTIETANTELDERYSRMHS
EVDAGQYVMVSMTDTGTGMSPDVIERAFDPFYTTKGPGKGTGLGLSQVYGYIKQSGGHIKIYSEIDRGTTVKIYLPRHVG
AMDARLNAAGAQPIPQGSVNDTILVVEDDENVRIMTAESLHELGYTVLQAASGMEALLLLEENREVDLIFTDIVMPQMSG
RQLADIVQEKWPAIRILYTTGYTRNAIVHNGVLDHGVSLLAKPFSLEQLAHKIRELLNVPAKMENERT

Sequences:

>Translated_548_residues
MDLLSATDWLRHRPGYTYPLAVAFVGLTFLLRLAASDYLSGFPFLSFLPAILLASFIGGAGPGLVAAILAAFIVQQFFVE
PHNIFWPVSAGQWVGLSTYLINAVIIIGLMEMIIIAHRRQSRLRNELNGFNTRLEQTVVQRTAELRHEMEENAAAQAQVR
QLQKMETIGQLTGGVAHDFNNMLAIIIGNLDLAQRRMTGHEDPRVLNSIQNAKDGAQRAAVLTARLLAFSRQQPLAPEVI
DLNKLVGGMSELLRRTLGEQIRIETVLAGGLWPSFADLSQLENAILNLAVNARDAMPGGGHLTIETANTELDERYSRMHS
EVDAGQYVMVSMTDTGTGMSPDVIERAFDPFYTTKGPGKGTGLGLSQVYGYIKQSGGHIKIYSEIDRGTTVKIYLPRHVG
AMDARLNAAGAQPIPQGSVNDTILVVEDDENVRIMTAESLHELGYTVLQAASGMEALLLLEENREVDLIFTDIVMPQMSG
RQLADIVQEKWPAIRILYTTGYTRNAIVHNGVLDHGVSLLAKPFSLEQLAHKIRELLNVPAKMENERT
>Mature_548_residues
MDLLSATDWLRHRPGYTYPLAVAFVGLTFLLRLAASDYLSGFPFLSFLPAILLASFIGGAGPGLVAAILAAFIVQQFFVE
PHNIFWPVSAGQWVGLSTYLINAVIIIGLMEMIIIAHRRQSRLRNELNGFNTRLEQTVVQRTAELRHEMEENAAAQAQVR
QLQKMETIGQLTGGVAHDFNNMLAIIIGNLDLAQRRMTGHEDPRVLNSIQNAKDGAQRAAVLTARLLAFSRQQPLAPEVI
DLNKLVGGMSELLRRTLGEQIRIETVLAGGLWPSFADLSQLENAILNLAVNARDAMPGGGHLTIETANTELDERYSRMHS
EVDAGQYVMVSMTDTGTGMSPDVIERAFDPFYTTKGPGKGTGLGLSQVYGYIKQSGGHIKIYSEIDRGTTVKIYLPRHVG
AMDARLNAAGAQPIPQGSVNDTILVVEDDENVRIMTAESLHELGYTVLQAASGMEALLLLEENREVDLIFTDIVMPQMSG
RQLADIVQEKWPAIRILYTTGYTRNAIVHNGVLDHGVSLLAKPFSLEQLAHKIRELLNVPAKMENERT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28.8, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=30.0411522633745, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=27.2340425531915, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=398, Percent_Identity=22.3618090452261, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=224, Percent_Identity=29.0178571428571, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60271; Mature: 60271

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLSATDWLRHRPGYTYPLAVAFVGLTFLLRLAASDYLSGFPFLSFLPAILLASFIGGA
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
GPGLVAAILAAFIVQQFFVEPHNIFWPVSAGQWVGLSTYLINAVIIIGLMEMIIIAHRRQ
CHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLRNELNGFNTRLEQTVVQRTAELRHEMEENAAAQAQVRQLQKMETIGQLTGGVAHDFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
NMLAIIIGNLDLAQRRMTGHEDPRVLNSIQNAKDGAQRAAVLTARLLAFSRQQPLAPEVI
CEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
DLNKLVGGMSELLRRTLGEQIRIETVLAGGLWPSFADLSQLENAILNLAVNARDAMPGGG
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCC
HLTIETANTELDERYSRMHSEVDAGQYVMVSMTDTGTGMSPDVIERAFDPFYTTKGPGKG
EEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCC
TGLGLSQVYGYIKQSGGHIKIYSEIDRGTTVKIYLPRHVGAMDARLNAAGAQPIPQGSVN
CCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCCC
DTILVVEDDENVRIMTAESLHELGYTVLQAASGMEALLLLEENREVDLIFTDIVMPQMSG
CEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECHHCCCCCC
RQLADIVQEKWPAIRILYTTGYTRNAIVHNGVLDHGVSLLAKPFSLEQLAHKIRELLNVP
HHHHHHHHHCCCEEEEEEECCCCCCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
AKMENERT
CCCCCCCC
>Mature Secondary Structure
MDLLSATDWLRHRPGYTYPLAVAFVGLTFLLRLAASDYLSGFPFLSFLPAILLASFIGGA
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
GPGLVAAILAAFIVQQFFVEPHNIFWPVSAGQWVGLSTYLINAVIIIGLMEMIIIAHRRQ
CHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLRNELNGFNTRLEQTVVQRTAELRHEMEENAAAQAQVRQLQKMETIGQLTGGVAHDFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
NMLAIIIGNLDLAQRRMTGHEDPRVLNSIQNAKDGAQRAAVLTARLLAFSRQQPLAPEVI
CEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
DLNKLVGGMSELLRRTLGEQIRIETVLAGGLWPSFADLSQLENAILNLAVNARDAMPGGG
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCC
HLTIETANTELDERYSRMHSEVDAGQYVMVSMTDTGTGMSPDVIERAFDPFYTTKGPGKG
EEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCC
TGLGLSQVYGYIKQSGGHIKIYSEIDRGTTVKIYLPRHVGAMDARLNAAGAQPIPQGSVN
CCCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCCC
DTILVVEDDENVRIMTAESLHELGYTVLQAASGMEALLLLEENREVDLIFTDIVMPQMSG
CEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECHHCCCCCC
RQLADIVQEKWPAIRILYTTGYTRNAIVHNGVLDHGVSLLAKPFSLEQLAHKIRELLNVP
HHHHHHHHHCCCEEEEEEECCCCCCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
AKMENERT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA