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The map label for this gene is lrp [H]

Identifier: 209548548

GI number: 209548548

Start: 968195

End: 968668

Strand: Direct

Name: lrp [H]

Synonym: Rleg2_0945

Alternate gene names: 209548548

Gene position: 968195-968668 (Clockwise)

Preceding gene: 209548546

Following gene: 209548551

Centisome position: 21.34

GC content: 59.7

Gene sequence:

>474_bases
ATGCCAAATCTCGATAAATTCGATATCGCCATCCTGAAGTGCCTGCAGGAGGATGCGCGGGCGACCAATGTCGAGATCGC
CGAGAAGGTGAACCTTTCGCCATCGCCCTGCCTGCGCCGCATCCGCAATCTCGAACGCTCCGGCATCATCCGCGGCTACA
CCGCCGATATCGACCGCAAGGAAGTCGGGCTCGGCCTGACGGTCTTCGTCGAGTTCAAGGTCGTCCATCACAGCCGCGAG
AATTCCGAGGCGCAGCAAAAGGCGCTGCTCGCCATCCCCGAGATCGTCTCCTGCTTCCTGATTTCGGGCACGGCAGATTT
CCTCGCAGAAGTGGTGGTGGAGGATCTCGCCGCCTACGAGCGGCTTCTGACAGAAACGCTGCTGACCCTGCCGAATGTCA
GCGACATCCGCTCCAACTTCGCCATCCGCAGCATCAAGACACATGGGCCGTTGAAGCTGCCCGAGGGAAAATAA

Upstream 100 bases:

>100_bases
AGATTAGTCCGAGAGGGCAGGGCATGTCCTTGCTATCTCTGGCTCAAAAATCATGCTACGCGCAATCTTCTGCCAAATGA
TGCCAACGGGAATCGCGAAA

Downstream 100 bases:

>100_bases
ATCCTCTCGGGCTTGTTGCCATTTGCGGGTGCTACAATAGCGTCCCGCTGAGGATGAGCAGGGCCACCGAGAAGTAGATG
ACGAGCCCGGTGACGTCGAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MPNLDKFDIAILKCLQEDARATNVEIAEKVNLSPSPCLRRIRNLERSGIIRGYTADIDRKEVGLGLTVFVEFKVVHHSRE
NSEAQQKALLAIPEIVSCFLISGTADFLAEVVVEDLAAYERLLTETLLTLPNVSDIRSNFAIRSIKTHGPLKLPEGK

Sequences:

>Translated_157_residues
MPNLDKFDIAILKCLQEDARATNVEIAEKVNLSPSPCLRRIRNLERSGIIRGYTADIDRKEVGLGLTVFVEFKVVHHSRE
NSEAQQKALLAIPEIVSCFLISGTADFLAEVVVEDLAAYERLLTETLLTLPNVSDIRSNFAIRSIKTHGPLKLPEGK
>Mature_156_residues
PNLDKFDIAILKCLQEDARATNVEIAEKVNLSPSPCLRRIRNLERSGIIRGYTADIDRKEVGLGLTVFVEFKVVHHSREN
SEAQQKALLAIPEIVSCFLISGTADFLAEVVVEDLAAYERLLTETLLTLPNVSDIRSNFAIRSIKTHGPLKLPEGK

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=41.6107382550336, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17469; Mature: 17338

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLDKFDIAILKCLQEDARATNVEIAEKVNLSPSPCLRRIRNLERSGIIRGYTADIDRK
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECCCCHH
EVGLGLTVFVEFKVVHHSRENSEAQQKALLAIPEIVSCFLISGTADFLAEVVVEDLAAYE
HHCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLLTETLLTLPNVSDIRSNFAIRSIKTHGPLKLPEGK
HHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCCCCCC
>Mature Secondary Structure 
PNLDKFDIAILKCLQEDARATNVEIAEKVNLSPSPCLRRIRNLERSGIIRGYTADIDRK
CCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECCCCHH
EVGLGLTVFVEFKVVHHSRENSEAQQKALLAIPEIVSCFLISGTADFLAEVVVEDLAAYE
HHCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLLTETLLTLPNVSDIRSNFAIRSIKTHGPLKLPEGK
HHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]