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The map label for this gene is degP1 [H]

Identifier: 209548527

GI number: 209548527

Start: 938095

End: 939678

Strand: Direct

Name: degP1 [H]

Synonym: Rleg2_0924

Alternate gene names: 209548527

Gene position: 938095-939678 (Clockwise)

Preceding gene: 209548526

Following gene: 209548528

Centisome position: 20.67

GC content: 64.9

Gene sequence:

>1584_bases
ATGCTCAAGAATTTCAACGGACGTCCGTCCCTCGCCACTGTGCTCAAGGCTTCTACCGTCGCCGGTATCGCAGCCGCTGT
GCTCGCAACCGGCGTTCCGCTCGAAATCACCCGGTCTTATGCCGAAGCCGTCAAGGTTCAGGCGCCTGCCGTGCCGAGCT
TCGCCAATGTCGTCGATGCCGTTTCGCCGGCCGTCGTTTCCGTCCGCGTCGAAAACCGCGTCAATCCCGTCTCCGACAAT
GACGGCTTCTCCATCGAAGGCCGCGGCTTCGACGATCTTCCCGATGATCATCCGCTGAAGCGCTTCTTCAAGCAGTTCGG
TGGCCAGGACCCAAGTGATCAGCAGGGCCATCAGCGGCGCTTCGGCCAGAACGGCCCGGGTGGCCAAAATGGCCCCGGCG
GCAAGGGCCGTCTGCGTCCGGTCGCTCAGGGGTCCGGCTTCTTCATCTCCGAGGATGGCTACATCGTTACCAACAACCAC
GTCGTTTCCGACGGCCAGGCCTTCGTCGCTGTCATGAATGACGGCACCGAACTCGATGCCAAGCTGATCGGCAAGGATCC
GCGCACCGATCTCGCCGTCCTCAAGGTCGACGGCAAGGGCAAGAAGTTCACCTACGTCAACTGGGCCGATGACAACAATG
TCCGCGTCGGCGACTGGGTCGTCGCCGTCGGCAACCCCTTCGGCCTCGGCGGCACGGTCACGGCCGGCATCGTTTCGGCC
CGCGGCCGCGATATCGGCTCTGGCCCCTATGACGATTACCTGCAGGTGGATGCCGCCGTGAACCGCGGCAACTCCGGTGG
CCCAACCTTCAACCTCAGCGGCGAAGTCGTCGGCATCAACACCGCGATCTTCTCGCCGTCCGGCGGCAGCGTCGGTATCG
CCTTCGCCATTCCGGCCTCGACAGCCAGGGATGTCGTCGCCGATCTGATGAAGGACGGCCAGGTTTCGCGTGGCTGGCTG
GGTGTCCAGATCCAGCCGGTGACCAAGGATATCGCCGAATCCATCGGCCTTTCCGAGCCGAGCGGCGCCCTTGTCGTCGC
GCCCCAGGCCGGGTCGCCCGGCGACAAGGCCGGCATGAAGGCCGGCGACGTCGTTACCGCGCTGAACGGTGAAACGATCA
AGGATGCGCGTGACCTCAGCCGCCGCATTGGCGCGATGCAGCCGGGCAGCAAGGTCGAGCTTTCGGTCTGGCGTGCCGGC
AAGGCCCAGCCTCTGACCGTCGAACTCGGCACGCTGCCGGCCGACCAGAAGGATGCGAACGCCGATGACAACAGCCAGCC
GCAGCAGCCGGAGGCACCGGCGTCCGAAAAGGCGCTTGCCGATCTCGGCCTGACGGTCGGTCCTTCCGATGACGGCAAGG
GCCTGGCGATCACCGGCATCGACCCGGACTCCGACGCCGCCGACAAGGGCATCAAGGAAGGCGAGAAGATCACCTCGGTC
AACAACCAGGAAGTCTCCAGCCCCGCCGATGTCGTCAAGGTGCTGAACCAGGCCAAGAAGGACGGCCGCACCCGGGCGCT
CTTCCAGATCCAGTCGAGCGAAGGAAGCCGTTTCGTCGCTCTTCCGATCAACGGCCAGGGCTGA

Upstream 100 bases:

>100_bases
GCCGGACAGTTCGCAGTAAGGTGCGCCATCCTATATCTTGATGCATCGACTGATCCGGCGCTGCCGGGCTGAAGATTTAA
GAACAAGAGAAGGTGCACCA

Downstream 100 bases:

>100_bases
TCCCTCAAGAAAACAGCAGCCGTGCGGATGAAAATCCGCGCGGCTGATTCTTCTGACCTTTGAAGGATGATCGCGATGAG
CGCCGCCCCGCAGGAAGATG

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MLKNFNGRPSLATVLKASTVAGIAAAVLATGVPLEITRSYAEAVKVQAPAVPSFANVVDAVSPAVVSVRVENRVNPVSDN
DGFSIEGRGFDDLPDDHPLKRFFKQFGGQDPSDQQGHQRRFGQNGPGGQNGPGGKGRLRPVAQGSGFFISEDGYIVTNNH
VVSDGQAFVAVMNDGTELDAKLIGKDPRTDLAVLKVDGKGKKFTYVNWADDNNVRVGDWVVAVGNPFGLGGTVTAGIVSA
RGRDIGSGPYDDYLQVDAAVNRGNSGGPTFNLSGEVVGINTAIFSPSGGSVGIAFAIPASTARDVVADLMKDGQVSRGWL
GVQIQPVTKDIAESIGLSEPSGALVVAPQAGSPGDKAGMKAGDVVTALNGETIKDARDLSRRIGAMQPGSKVELSVWRAG
KAQPLTVELGTLPADQKDANADDNSQPQQPEAPASEKALADLGLTVGPSDDGKGLAITGIDPDSDAADKGIKEGEKITSV
NNQEVSSPADVVKVLNQAKKDGRTRALFQIQSSEGSRFVALPINGQG

Sequences:

>Translated_527_residues
MLKNFNGRPSLATVLKASTVAGIAAAVLATGVPLEITRSYAEAVKVQAPAVPSFANVVDAVSPAVVSVRVENRVNPVSDN
DGFSIEGRGFDDLPDDHPLKRFFKQFGGQDPSDQQGHQRRFGQNGPGGQNGPGGKGRLRPVAQGSGFFISEDGYIVTNNH
VVSDGQAFVAVMNDGTELDAKLIGKDPRTDLAVLKVDGKGKKFTYVNWADDNNVRVGDWVVAVGNPFGLGGTVTAGIVSA
RGRDIGSGPYDDYLQVDAAVNRGNSGGPTFNLSGEVVGINTAIFSPSGGSVGIAFAIPASTARDVVADLMKDGQVSRGWL
GVQIQPVTKDIAESIGLSEPSGALVVAPQAGSPGDKAGMKAGDVVTALNGETIKDARDLSRRIGAMQPGSKVELSVWRAG
KAQPLTVELGTLPADQKDANADDNSQPQQPEAPASEKALADLGLTVGPSDDGKGLAITGIDPDSDAADKGIKEGEKITSV
NNQEVSSPADVVKVLNQAKKDGRTRALFQIQSSEGSRFVALPINGQG
>Mature_527_residues
MLKNFNGRPSLATVLKASTVAGIAAAVLATGVPLEITRSYAEAVKVQAPAVPSFANVVDAVSPAVVSVRVENRVNPVSDN
DGFSIEGRGFDDLPDDHPLKRFFKQFGGQDPSDQQGHQRRFGQNGPGGQNGPGGKGRLRPVAQGSGFFISEDGYIVTNNH
VVSDGQAFVAVMNDGTELDAKLIGKDPRTDLAVLKVDGKGKKFTYVNWADDNNVRVGDWVVAVGNPFGLGGTVTAGIVSA
RGRDIGSGPYDDYLQVDAAVNRGNSGGPTFNLSGEVVGINTAIFSPSGGSVGIAFAIPASTARDVVADLMKDGQVSRGWL
GVQIQPVTKDIAESIGLSEPSGALVVAPQAGSPGDKAGMKAGDVVTALNGETIKDARDLSRRIGAMQPGSKVELSVWRAG
KAQPLTVELGTLPADQKDANADDNSQPQQPEAPASEKALADLGLTVGPSDDGKGLAITGIDPDSDAADKGIKEGEKITSV
NNQEVSSPADVVKVLNQAKKDGRTRALFQIQSSEGSRFVALPINGQG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=256, Percent_Identity=35.9375, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI24308541, Length=262, Percent_Identity=35.4961832061069, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI22129776, Length=272, Percent_Identity=34.1911764705882, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI7019477, Length=260, Percent_Identity=35.7692307692308, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1789629, Length=476, Percent_Identity=38.2352941176471, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1786356, Length=452, Percent_Identity=37.1681415929204, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1789630, Length=276, Percent_Identity=35.5072463768116, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324206, Length=302, Percent_Identity=27.4834437086093, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=32.5259515570934, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 54538; Mature: 54538

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNFNGRPSLATVLKASTVAGIAAAVLATGVPLEITRSYAEAVKVQAPAVPSFANVVDA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCHHHHHHHH
VSPAVVSVRVENRVNPVSDNDGFSIEGRGFDDLPDDHPLKRFFKQFGGQDPSDQQGHQRR
CCCEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
FGQNGPGGQNGPGGKGRLRPVAQGSGFFISEDGYIVTNNHVVSDGQAFVAVMNDGTELDA
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCEEEECCEEEECCCEEEEEECCCCCCCC
KLIGKDPRTDLAVLKVDGKGKKFTYVNWADDNNVRVGDWVVAVGNPFGLGGTVTAGIVSA
EEECCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHHH
RGRDIGSGPYDDYLQVDAAVNRGNSGGPTFNLSGEVVGINTAIFSPSGGSVGIAFAIPAS
CCCCCCCCCCCCCEEEEHHHCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEEECCC
TARDVVADLMKDGQVSRGWLGVQIQPVTKDIAESIGLSEPSGALVVAPQAGSPGDKAGMK
HHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCC
AGDVVTALNGETIKDARDLSRRIGAMQPGSKVELSVWRAGKAQPLTVELGTLPADQKDAN
CCCEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCC
ADDNSQPQQPEAPASEKALADLGLTVGPSDDGKGLAITGIDPDSDAADKGIKEGEKITSV
CCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCEEEEECCCCCCCHHHHHHHCCCCEECC
NNQEVSSPADVVKVLNQAKKDGRTRALFQIQSSEGSRFVALPINGQG
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure
MLKNFNGRPSLATVLKASTVAGIAAAVLATGVPLEITRSYAEAVKVQAPAVPSFANVVDA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCHHHHHHHH
VSPAVVSVRVENRVNPVSDNDGFSIEGRGFDDLPDDHPLKRFFKQFGGQDPSDQQGHQRR
CCCEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
FGQNGPGGQNGPGGKGRLRPVAQGSGFFISEDGYIVTNNHVVSDGQAFVAVMNDGTELDA
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCEEEECCEEEECCCEEEEEECCCCCCCC
KLIGKDPRTDLAVLKVDGKGKKFTYVNWADDNNVRVGDWVVAVGNPFGLGGTVTAGIVSA
EEECCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHHH
RGRDIGSGPYDDYLQVDAAVNRGNSGGPTFNLSGEVVGINTAIFSPSGGSVGIAFAIPAS
CCCCCCCCCCCCCEEEEHHHCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEEECCC
TARDVVADLMKDGQVSRGWLGVQIQPVTKDIAESIGLSEPSGALVVAPQAGSPGDKAGMK
HHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCC
AGDVVTALNGETIKDARDLSRRIGAMQPGSKVELSVWRAGKAQPLTVELGTLPADQKDAN
CCCEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCC
ADDNSQPQQPEAPASEKALADLGLTVGPSDDGKGLAITGIDPDSDAADKGIKEGEKITSV
CCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCEEEEECCCCCCCHHHHHHHCCCCEECC
NNQEVSSPADVVKVLNQAKKDGRTRALFQIQSSEGSRFVALPINGQG
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]