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The map label for this gene is ilvE [H]

Identifier: 209548435

GI number: 209548435

Start: 850634

End: 851521

Strand: Direct

Name: ilvE [H]

Synonym: Rleg2_0832

Alternate gene names: 209548435

Gene position: 850634-851521 (Clockwise)

Preceding gene: 209548433

Following gene: 209548437

Centisome position: 18.74

GC content: 65.54

Gene sequence:

>888_bases
ATGGCCGTCGATACATCACCGCGTTCAACCACCTGGACTCATGTCGACGGGGAGTGGCTTTCCGGCAATCCGCCGCTGAT
CGGGCCGACCTCGCATGCCATGTGGCTCGGCTCCACGGTTTTCGACGGCGCCCGCTGGTTCGACGGCATCGCGCCGGATC
TCGACCTGCATTGCCAGCGCATCAACCGCTCCGCGCTCGCCATGGGGCTGAAGCCGGTGAAATCAGCCGAGGAAATCGCC
GCGCTCGCCTGGGAAGGCGTTGAAAAATTCGACGGCGCCACGCCGATCTACATCAAGCCGATGTATTGGGGCGAACATGG
TTCGCCCGGCAGCGTCGTCTCCGTCGATGCGGAATCGACCCGCTTCGCGCTCTGCCTGTTCGAGGCGCCGATGGGCGGCC
ATGGCGGCACCAGCCTCACCGTCTCGCCCTATCGCCGCCCGTCGCCTGAGACGGCGATGACCGAGGCGAAGACCGGCTCG
CTCTATCCGAACAGCGGCCGCATGATCGCCGAAGCCCGCGGCCGCGGCTTCGACAATGCGCTGGTGCGCGATCTCAACGG
CAACGTCGTCGAGACCGCCTCGTCCAACGTCTTCCTGGTGCGCGACGGCGTGGTGATGACGCCCGCCGCCAACCGCACCT
TCCTCGCCGGTATCACCCGCGCCCGCGTTATGCACCTCTTGCGCAAGGCCGGCTTCGACGTCGTCGAAGCCACCCTGTCC
GTCGAGGATTTCCTCGCCGCCGACGAAATCTTCACCACCGGCAACTACTCCAAAATCGTCGGCGTCATCCGCCTCGACGA
CCGCAATCTCCAGGAAGGCCCGGTCACCCGCAAGGCGCTGGATCTCTACATGGACTGGGCCCACGTAAGAAGCGAGAGCG
AGGAGTGA

Upstream 100 bases:

>100_bases
CCTCAACATTTTCTTGCTTCCGCATTTGCCGCCCGGATTTGTCCTTGACCCGGTTCGCCGCAGGGGTTTTTGCTGTGCCG
ACTTCAGAGGGGAGGGCAAC

Downstream 100 bases:

>100_bases
GGGGTGAGGAATGGTCCCGCGGAGCGGGAGCAATCGATCCAGTGAATCGATTGCAATGACGAACGCCCGGAGCGCAAGCG
AAGGGCAGGGTGGTTCGGAG

Product: aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAVDTSPRSTTWTHVDGEWLSGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCQRINRSALAMGLKPVKSAEEIA
ALAWEGVEKFDGATPIYIKPMYWGEHGSPGSVVSVDAESTRFALCLFEAPMGGHGGTSLTVSPYRRPSPETAMTEAKTGS
LYPNSGRMIAEARGRGFDNALVRDLNGNVVETASSNVFLVRDGVVMTPAANRTFLAGITRARVMHLLRKAGFDVVEATLS
VEDFLAADEIFTTGNYSKIVGVIRLDDRNLQEGPVTRKALDLYMDWAHVRSESEE

Sequences:

>Translated_295_residues
MAVDTSPRSTTWTHVDGEWLSGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCQRINRSALAMGLKPVKSAEEIA
ALAWEGVEKFDGATPIYIKPMYWGEHGSPGSVVSVDAESTRFALCLFEAPMGGHGGTSLTVSPYRRPSPETAMTEAKTGS
LYPNSGRMIAEARGRGFDNALVRDLNGNVVETASSNVFLVRDGVVMTPAANRTFLAGITRARVMHLLRKAGFDVVEATLS
VEDFLAADEIFTTGNYSKIVGVIRLDDRNLQEGPVTRKALDLYMDWAHVRSESEE
>Mature_294_residues
AVDTSPRSTTWTHVDGEWLSGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCQRINRSALAMGLKPVKSAEEIAA
LAWEGVEKFDGATPIYIKPMYWGEHGSPGSVVSVDAESTRFALCLFEAPMGGHGGTSLTVSPYRRPSPETAMTEAKTGSL
YPNSGRMIAEARGRGFDNALVRDLNGNVVETASSNVFLVRDGVVMTPAANRTFLAGITRARVMHLLRKAGFDVVEATLSV
EDFLAADEIFTTGNYSKIVGVIRLDDRNLQEGPVTRKALDLYMDWAHVRSESEE

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=274, Percent_Identity=30.2919708029197, Blast_Score=110, Evalue=8e-26,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32075; Mature: 31943

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDTSPRSTTWTHVDGEWLSGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCQR
CCCCCCCCCCEEEEECCCEECCCCCEECCCCCCEEECCHHHCCHHHHCCCCCCHHHHHHH
INRSALAMGLKPVKSAEEIAALAWEGVEKFDGATPIYIKPMYWGEHGSPGSVVSVDAEST
HCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEECCCCC
RFALCLFEAPMGGHGGTSLTVSPYRRPSPETAMTEAKTGSLYPNSGRMIAEARGRGFDNA
EEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCHH
LVRDLNGNVVETASSNVFLVRDGVVMTPAANRTFLAGITRARVMHLLRKAGFDVVEATLS
HHHHCCCCEEEECCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VEDFLAADEIFTTGNYSKIVGVIRLDDRNLQEGPVTRKALDLYMDWAHVRSESEE
HHHHHHHHHEEECCCHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVDTSPRSTTWTHVDGEWLSGNPPLIGPTSHAMWLGSTVFDGARWFDGIAPDLDLHCQR
CCCCCCCCCEEEEECCCEECCCCCEECCCCCCEEECCHHHCCHHHHCCCCCCHHHHHHH
INRSALAMGLKPVKSAEEIAALAWEGVEKFDGATPIYIKPMYWGEHGSPGSVVSVDAEST
HCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEECCCCC
RFALCLFEAPMGGHGGTSLTVSPYRRPSPETAMTEAKTGSLYPNSGRMIAEARGRGFDNA
EEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCHH
LVRDLNGNVVETASSNVFLVRDGVVMTPAANRTFLAGITRARVMHLLRKAGFDVVEATLS
HHHHCCCCEEEECCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VEDFLAADEIFTTGNYSKIVGVIRLDDRNLQEGPVTRKALDLYMDWAHVRSESEE
HHHHHHHHHEEECCCHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]