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The map label for this gene is cph2 [H]

Identifier: 209548401

GI number: 209548401

Start: 817599

End: 819467

Strand: Direct

Name: cph2 [H]

Synonym: Rleg2_0798

Alternate gene names: 209548401

Gene position: 817599-819467 (Clockwise)

Preceding gene: 209548399

Following gene: 209548403

Centisome position: 18.02

GC content: 59.55

Gene sequence:

>1869_bases
GTGCCTTGGCAAGTCTTGATCGGAAATGTGGCTGCGGTAGCGCTCGTCATTTCGGTGTGGATGCACCTGCATTACAAGTT
CTACCGCCTTTCCAAGGTCCAGGCAGAACTTGGCTTCGGCTTGATGATGGGCCTTGGGGCAGTCTTGTCGATGCTGCTGT
CCGTCGAGGTCGATAGCGGCTATTATCTCGACCTGCGTTCGACCTTGCTGGCGGTTTCGGCCGTCTACGGTGGTCCGCTG
GCGGTTCTGATGACGGCAGTCCTCACCTGCGTCCAGAGGATCTCCATGGGTGGCGCCGGTGTCGAACCGGCATTGATCTC
GATCGTGCTGGTGTCCGTGTTTGGCCTGGCGCTCCACTTCCTGTTCGGCAGGGGCTCGGTGGATGTCAGAAAGGCACTTG
CCTGTGCGGTCATGGTGGCCACGGTCACACTGGCGATGAGCATTTTCCATCGAGGTGGCTGGTCGCATATCACCACCGTT
AGCCTTGCCGGAATAGGCGTGAAGTTCGCCGCGACCTTGGCCGCGGCATGCGTCATCACCTATTTCCATGCCTTCACCCT
CGAGCGTGATATCTTGAAGGCCGCTTTGACCCAGGCGCCTGATTTCCACTATGTCAAAGACCGCAATAGCCGGTTCGTCG
TCACCAACCTCAACGTCGCGCGAAACCACGACCGCACCAAATCTTCGGAGATGGTCGGCCTGACGGATTTCGATCTTTAT
CCTCGCGAGATGGCGCAAGCATTCTTCGATCGCGAGCAGGAAATCATGGCGAGCGGGGAAGCCCTGGTGGATTTCGAGGA
GCCTCTTGTTGAAGAAAACGGCCGGGAGCGTTGGTTCCTGACGTCGAAAATCCCGCTGCGAAACCGCCACGGCGATCTGG
TTGGACTTGCCGGCGTGACCCGCGATATCACCGAGAAAAAACGTCTGATTCAGGAAGCCCTCGACAGCAAGACTGTGCTT
TCCCAAGCGATGACCGAAATGTCCGATGGGCTTGCCATGTTCAATCCCGAGGGCCGGCTGGTGTTTTGCAACGATCAATA
TCGTGCCGCCTTTCCCCGTTCCGCCCATGCCAGACAACCCGGCACCGACATAACCGCTATCCTGCAAGCGGTCGTGCGCA
GTGGTGAGCGGGTCGATGTGAGCCCGGATGCCGGCGATGACTGGATCGAGACCTCCGCGGCGCAGCTTTTCCTGACTCAG
GATAGCGAAATACCGATGTTCGATGGGCGGTGGCTCAGACAGCGCACGCGTTTGGCCGCCGATGGCTCCGCCCTGGTGGT
GGTTTCGGATATCACCTCGATGAAGCATTCCGAGGAAAGGCTGACGCAACTCGCTCTGAAGATGAAGGGGCTGGCCGACA
CCGACGCATTGACCGGTATTGCCAATCGAAGAGTGTTCAACGAGGCGATCTCGGAGGAGTTTGCACGCGTCCGTCGAGCC
GAATCCTCTCTCAGCCTGTTGCTGATCGATGTCGATCACTTCAAGGCTTACAACGATACCTACGGTCACCTCGAAGGAGA
CAACTGCCTGAGGATGATCGGCGAGATTCTCAGGTCCATTGCCAAGCGGCCCTCAGACCTCGCAGCGCGATTTGGCGGAG
AGGAGTTCGCCATACTGCTTCCCGGCACGGACCGGGATGGCGCGCTGCGGCTGGCCAGGATGCTGCGCTCGGCGTTGCAT
CGGCGCGCAATACCACATAGCGAAAGCAGCAAGGCGATCGTGACGGTGAGTATCGGTGTGGCCAACATCTGCGACAGATT
TGCGACGCCGGCAGAACTGGTCTCGGCCGCGGACCAGGCGCTCTACGCGGCAAAGAAGCACGGACGCGACCGCGTCGAGG
CCGCCGCGCATCAGGCAAGAGCGGCGTAA

Upstream 100 bases:

>100_bases
ATGCCAAGCCCATGAGGGCGCCAACCGGCAACGTCTCCAGCCAATCGGATTTCATCAACGCGTTTTCATTAAGTAACTGT
AAATATTAGAGGAATCTGTT

Downstream 100 bases:

>100_bases
GCCGCATACTGTCGTTGAGGACGGACTTCATTTCGCAAGCTTGCCGATCGCCTCGATCTCGTTCGTCCATATGCCCGCCG
CATAGTCTGGCGGCAGTCGC

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MPWQVLIGNVAAVALVISVWMHLHYKFYRLSKVQAELGFGLMMGLGAVLSMLLSVEVDSGYYLDLRSTLLAVSAVYGGPL
AVLMTAVLTCVQRISMGGAGVEPALISIVLVSVFGLALHFLFGRGSVDVRKALACAVMVATVTLAMSIFHRGGWSHITTV
SLAGIGVKFAATLAAACVITYFHAFTLERDILKAALTQAPDFHYVKDRNSRFVVTNLNVARNHDRTKSSEMVGLTDFDLY
PREMAQAFFDREQEIMASGEALVDFEEPLVEENGRERWFLTSKIPLRNRHGDLVGLAGVTRDITEKKRLIQEALDSKTVL
SQAMTEMSDGLAMFNPEGRLVFCNDQYRAAFPRSAHARQPGTDITAILQAVVRSGERVDVSPDAGDDWIETSAAQLFLTQ
DSEIPMFDGRWLRQRTRLAADGSALVVVSDITSMKHSEERLTQLALKMKGLADTDALTGIANRRVFNEAISEEFARVRRA
ESSLSLLLIDVDHFKAYNDTYGHLEGDNCLRMIGEILRSIAKRPSDLAARFGGEEFAILLPGTDRDGALRLARMLRSALH
RRAIPHSESSKAIVTVSIGVANICDRFATPAELVSAADQALYAAKKHGRDRVEAAAHQARAA

Sequences:

>Translated_622_residues
MPWQVLIGNVAAVALVISVWMHLHYKFYRLSKVQAELGFGLMMGLGAVLSMLLSVEVDSGYYLDLRSTLLAVSAVYGGPL
AVLMTAVLTCVQRISMGGAGVEPALISIVLVSVFGLALHFLFGRGSVDVRKALACAVMVATVTLAMSIFHRGGWSHITTV
SLAGIGVKFAATLAAACVITYFHAFTLERDILKAALTQAPDFHYVKDRNSRFVVTNLNVARNHDRTKSSEMVGLTDFDLY
PREMAQAFFDREQEIMASGEALVDFEEPLVEENGRERWFLTSKIPLRNRHGDLVGLAGVTRDITEKKRLIQEALDSKTVL
SQAMTEMSDGLAMFNPEGRLVFCNDQYRAAFPRSAHARQPGTDITAILQAVVRSGERVDVSPDAGDDWIETSAAQLFLTQ
DSEIPMFDGRWLRQRTRLAADGSALVVVSDITSMKHSEERLTQLALKMKGLADTDALTGIANRRVFNEAISEEFARVRRA
ESSLSLLLIDVDHFKAYNDTYGHLEGDNCLRMIGEILRSIAKRPSDLAARFGGEEFAILLPGTDRDGALRLARMLRSALH
RRAIPHSESSKAIVTVSIGVANICDRFATPAELVSAADQALYAAKKHGRDRVEAAAHQARAA
>Mature_621_residues
PWQVLIGNVAAVALVISVWMHLHYKFYRLSKVQAELGFGLMMGLGAVLSMLLSVEVDSGYYLDLRSTLLAVSAVYGGPLA
VLMTAVLTCVQRISMGGAGVEPALISIVLVSVFGLALHFLFGRGSVDVRKALACAVMVATVTLAMSIFHRGGWSHITTVS
LAGIGVKFAATLAAACVITYFHAFTLERDILKAALTQAPDFHYVKDRNSRFVVTNLNVARNHDRTKSSEMVGLTDFDLYP
REMAQAFFDREQEIMASGEALVDFEEPLVEENGRERWFLTSKIPLRNRHGDLVGLAGVTRDITEKKRLIQEALDSKTVLS
QAMTEMSDGLAMFNPEGRLVFCNDQYRAAFPRSAHARQPGTDITAILQAVVRSGERVDVSPDAGDDWIETSAAQLFLTQD
SEIPMFDGRWLRQRTRLAADGSALVVVSDITSMKHSEERLTQLALKMKGLADTDALTGIANRRVFNEAISEEFARVRRAE
SSLSLLLIDVDHFKAYNDTYGHLEGDNCLRMIGEILRSIAKRPSDLAARFGGEEFAILLPGTDRDGALRLARMLRSALHR
RAIPHSESSKAIVTVSIGVANICDRFATPAELVSAADQALYAAKKHGRDRVEAAAHQARAA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=34.2541436464088, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081881, Length=198, Percent_Identity=40.4040404040404, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=37.2093023255814, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=37.1069182389937, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788381, Length=208, Percent_Identity=37.0192307692308, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787816, Length=166, Percent_Identity=37.3493975903614, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=34.2541436464088, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787541, Length=224, Percent_Identity=29.4642857142857, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787056, Length=165, Percent_Identity=32.7272727272727, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 68170; Mature: 68039

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWQVLIGNVAAVALVISVWMHLHYKFYRLSKVQAELGFGLMMGLGAVLSMLLSVEVDSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
YYLDLRSTLLAVSAVYGGPLAVLMTAVLTCVQRISMGGAGVEPALISIVLVSVFGLALHF
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LFGRGSVDVRKALACAVMVATVTLAMSIFHRGGWSHITTVSLAGIGVKFAATLAAACVIT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEHHHCCHHHHHHHHHHHHHH
YFHAFTLERDILKAALTQAPDFHYVKDRNSRFVVTNLNVARNHDRTKSSEMVGLTDFDLY
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECHHHHCCCCCCCCCEECCCCCCCC
PREMAQAFFDREQEIMASGEALVDFEEPLVEENGRERWFLTSKIPLRNRHGDLVGLAGVT
HHHHHHHHHCCHHHHHHCCCEEEECHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCH
RDITEKKRLIQEALDSKTVLSQAMTEMSDGLAMFNPEGRLVFCNDQYRAAFPRSAHARQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCHHHCCCCCCCCCCC
GTDITAILQAVVRSGERVDVSPDAGDDWIETSAAQLFLTQDSEIPMFDGRWLRQRTRLAA
CCHHHHHHHHHHCCCCEEECCCCCCCHHHHCCHHEEEEECCCCCCCCCCHHHHHHHHHCC
DGSALVVVSDITSMKHSEERLTQLALKMKGLADTDALTGIANRRVFNEAISEEFARVRRA
CCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESSLSLLLIDVDHFKAYNDTYGHLEGDNCLRMIGEILRSIAKRPSDLAARFGGEEFAILL
CCCCEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEE
PGTDRDGALRLARMLRSALHRRAIPHSESSKAIVTVSIGVANICDRFATPAELVSAADQA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHH
LYAAKKHGRDRVEAAAHQARAA
HHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PWQVLIGNVAAVALVISVWMHLHYKFYRLSKVQAELGFGLMMGLGAVLSMLLSVEVDSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
YYLDLRSTLLAVSAVYGGPLAVLMTAVLTCVQRISMGGAGVEPALISIVLVSVFGLALHF
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LFGRGSVDVRKALACAVMVATVTLAMSIFHRGGWSHITTVSLAGIGVKFAATLAAACVIT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEHHHCCHHHHHHHHHHHHHH
YFHAFTLERDILKAALTQAPDFHYVKDRNSRFVVTNLNVARNHDRTKSSEMVGLTDFDLY
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECHHHHCCCCCCCCCEECCCCCCCC
PREMAQAFFDREQEIMASGEALVDFEEPLVEENGRERWFLTSKIPLRNRHGDLVGLAGVT
HHHHHHHHHCCHHHHHHCCCEEEECHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCH
RDITEKKRLIQEALDSKTVLSQAMTEMSDGLAMFNPEGRLVFCNDQYRAAFPRSAHARQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCHHHCCCCCCCCCCC
GTDITAILQAVVRSGERVDVSPDAGDDWIETSAAQLFLTQDSEIPMFDGRWLRQRTRLAA
CCHHHHHHHHHHCCCCEEECCCCCCCHHHHCCHHEEEEECCCCCCCCCCHHHHHHHHHCC
DGSALVVVSDITSMKHSEERLTQLALKMKGLADTDALTGIANRRVFNEAISEEFARVRRA
CCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESSLSLLLIDVDHFKAYNDTYGHLEGDNCLRMIGEILRSIAKRPSDLAARFGGEEFAILL
CCCCEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEE
PGTDRDGALRLARMLRSALHRRAIPHSESSKAIVTVSIGVANICDRFATPAELVSAADQA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHH
LYAAKKHGRDRVEAAAHQARAA
HHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]