Click here to switch to the map view.

The map label for this gene is copR [H]

Identifier: 209548309

GI number: 209548309

Start: 728660

End: 729343

Strand: Reverse

Name: copR [H]

Synonym: Rleg2_0704

Alternate gene names: 209548309

Gene position: 729343-728660 (Counterclockwise)

Preceding gene: 209548310

Following gene: 209548308

Centisome position: 16.07

GC content: 64.47

Gene sequence:

>684_bases
ATGCGGATCCTGCTTATCGAGGACGATCGGAAGACGTCCGATTATATTGCCAAGGGCCTTTCCGAGGCAGGCCATGTCTG
CGACGTCTTCGGCGACGGCCGCGATGGGCTGTTTCAGGCGCAACGCGAAGCCTATGACGTCATCGTCGTCGATCGCATGC
TGCCGGGGCTCGATGGGCTGGCGATTATCCGGTCGCTCAGGGCCGCCAAGGTCGGCACATCGGCGCTGTTCCTCACCTCG
ATCGGCGGTGTCGACGACCGGGTCGAGGGGTTGGAGGCGGGCGGCGACGATTATCTCACCAAGCCCTTTGCCTTCTCCGA
GCTTCTGGCCCGCGTCAATGCGCTCGGCCGCCGGCCGCCGGTGCAGGAGCAGAAGACGGTGCTGAAGGTTGCCGATCTCG
AGCTCGATCTCATCCGCCGCGAAGCCCGCCGCGCCGGCCAGGCGATCGAGTTGCAGCCGCGCGAATTCACCCTGCTCGAA
GTGCTGATGCGCGGCGAAGGCCGGGTCATCACCAAGACGATGCTGTTGGAGCGGGTCTGGGATTTCCACTTCGATCCGAA
GACCAGCGTCGTCGAGACCCATATCAGCCGTTTGCGGGCCAAGGTCGACAGACCGTTCCAGGCCCAGCTTCTGCACACCG
TCCGCAACACCGGGTACAGCCTGCACGCGCCCAGGACAGGATGA

Upstream 100 bases:

>100_bases
CCGGCTGCCCAAGCCCCGCCCACCTTACAAATCCGTAAGTTGTCGCCCAGCCGCCGGCTCCGCTAGATTGCCCCCTCACC
TGCCGGGAATGATCGGGCTG

Downstream 100 bases:

>100_bases
TGCCGTCCGAAAACCGCACACATTTTTCCGCGTCATTCTCCAGCCTGCGCCGGAGCACGCCGTTCCGGCTTGCCGTCACC
TTCGTCGTGCTCTTCGTCGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRILLIEDDRKTSDYIAKGLSEAGHVCDVFGDGRDGLFQAQREAYDVIVVDRMLPGLDGLAIIRSLRAAKVGTSALFLTS
IGGVDDRVEGLEAGGDDYLTKPFAFSELLARVNALGRRPPVQEQKTVLKVADLELDLIRREARRAGQAIELQPREFTLLE
VLMRGEGRVITKTMLLERVWDFHFDPKTSVVETHISRLRAKVDRPFQAQLLHTVRNTGYSLHAPRTG

Sequences:

>Translated_227_residues
MRILLIEDDRKTSDYIAKGLSEAGHVCDVFGDGRDGLFQAQREAYDVIVVDRMLPGLDGLAIIRSLRAAKVGTSALFLTS
IGGVDDRVEGLEAGGDDYLTKPFAFSELLARVNALGRRPPVQEQKTVLKVADLELDLIRREARRAGQAIELQPREFTLLE
VLMRGEGRVITKTMLLERVWDFHFDPKTSVVETHISRLRAKVDRPFQAQLLHTVRNTGYSLHAPRTG
>Mature_227_residues
MRILLIEDDRKTSDYIAKGLSEAGHVCDVFGDGRDGLFQAQREAYDVIVVDRMLPGLDGLAIIRSLRAAKVGTSALFLTS
IGGVDDRVEGLEAGGDDYLTKPFAFSELLARVNALGRRPPVQEQKTVLKVADLELDLIRREARRAGQAIELQPREFTLLE
VLMRGEGRVITKTMLLERVWDFHFDPKTSVVETHISRLRAKVDRPFQAQLLHTVRNTGYSLHAPRTG

Specific function: Member of the two-component regulatory system CopS/CopR. Involved in the activation of copper resistance gene operon CopABCD. Phosphorylation of CopR by CopS would convert it into an active state to induce expression of the cop operon by binding to a spec

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=44.6428571428571, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=44.4444444444444, Blast_Score=194, Evalue=4e-51,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=40.2714932126697, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.0357142857143, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=33.6322869955157, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=32.7272727272727, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=34.375, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.9734513274336, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.5132743362832, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=30.8370044052863, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=29.2576419213974, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=31.063829787234, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.2576419213974, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=28.1818181818182, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25379; Mature: 25379

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDRKTSDYIAKGLSEAGHVCDVFGDGRDGLFQAQREAYDVIVVDRMLPGLDGL
CEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHEEEEHHHCCCCCHH
AIIRSLRAAKVGTSALFLTSIGGVDDRVEGLEAGGDDYLTKPFAFSELLARVNALGRRPP
HHHHHHHHHHHCCHHHEEHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
VQEQKTVLKVADLELDLIRREARRAGQAIELQPREFTLLEVLMRGEGRVITKTMLLERVW
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHH
DFHFDPKTSVVETHISRLRAKVDRPFQAQLLHTVRNTGYSLHAPRTG
HCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCC
>Mature Secondary Structure
MRILLIEDDRKTSDYIAKGLSEAGHVCDVFGDGRDGLFQAQREAYDVIVVDRMLPGLDGL
CEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHEEEEHHHCCCCCHH
AIIRSLRAAKVGTSALFLTSIGGVDDRVEGLEAGGDDYLTKPFAFSELLARVNALGRRPP
HHHHHHHHHHHCCHHHEEHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
VQEQKTVLKVADLELDLIRREARRAGQAIELQPREFTLLEVLMRGEGRVITKTMLLERVW
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHH
DFHFDPKTSVVETHISRLRAKVDRPFQAQLLHTVRNTGYSLHAPRTG
HCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449873; 8078459 [H]