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The map label for this gene is pqqL [C]

Identifier: 209548240

GI number: 209548240

Start: 658811

End: 660109

Strand: Reverse

Name: pqqL [C]

Synonym: Rleg2_0634

Alternate gene names: 209548240

Gene position: 660109-658811 (Counterclockwise)

Preceding gene: 209548241

Following gene: 209548239

Centisome position: 14.55

GC content: 63.82

Gene sequence:

>1299_bases
ATGACAGTTGAGTGCACCCGGCTGAAATCCGGGCTGACAGTAGTGACAGAAACCATGCCGCACCTTGAAAGCGTTGCGCT
CGGAGTCTGGATCAAATCGGGATCGCGTAACGAGACGGCAGACGAACACGGCATCGCCCACCTGCTTGAACACATGGCAT
TCAAGGGCACTGGGCGCCGCAGCGCCCGCCAGATCGCCGAGGAGATCGAGGATGTGGGCGGCGAGGTCAATGCCGCCACA
TCGACCGAGACGACCTCCTACTACGCCCGCGTGCTCAAGGACCACGTGCCGCTCGCCGTCGATATCCTCGCCGACATCCT
GACGGAATCGGCCTTCGAGGAGGAGGAGCTTGAGCGTGAGAAGCAGGTGATCCTGCAGGAGATCAACGCCGCCAACGACA
CGCCCGACGACGTGGTGTTCGACCGGTTCTCCGAGGTCGCCTATCGCGACCAGACGCTCGGCCGGGCCATCCTCGGCACG
CCGGAGACCGTCGTCTCCTTCACGCCGCAGCAGATCCGCGGCTATCTCGGCCGCAACTACACGACCGACCGCATGTTCGT
CGTCGCTACCGGCGCCGTCGAGCATGACGAATTCGTCCGCATGGTCGAGGATCGTTTCGCCAGCCTGCCGAGCGAGCCTT
CGGCGCCGCCGGTCATGGAAGCGGCGCGTTATATCGGCGGCAGCGTGCGCGAACCGCGCGACCTGATGGACGCGCAGATC
CTGCTCGGTTTCGAGGGCAAACCCTATCATGCCCGCGATTTCTACTGTTCGCAGATCCTCGCCAATATCCTCGGCGGCGG
CATGTCTTCGCGGCTGTTCCAGGAGGTGCGCGAGTTCCGCGGTCTCTGTTATTCCGTCTATGCCTTCCACTGGGGCTTTT
CCGACACCGGCATCTTCGGCATTCATGCCGCAACCGGCGGCGAAAACCTGCCGCAGCTGGTGCCCGTCATCATCGACGAG
CTGCACAAATCCGCCGACCAGATCCACCAGAAGGAAATCGAGCGCGCCCGCGCCCAGATCCGCGCCCAGTTGCTGATGGG
CCAGGAAAGCCCGGCCTCGCGCGCCGGCCAGATCGCCAGGCAGATGATGCTTTACGGCCGGCCGATCTCCAATATGGAGA
TGATGGAACGGCTTGAGGGCATCACCATCGAGCGGCTGACGGATCTCGCCGGCCGGCTGTTCTACGACACGGTGCCGACG
CTTTCGGCAATCGGTCCGCTGGAACAGCTCGCGCCGATGGAAGACATCACCGCTTCGCTTTCGGTCCCGGCACCGAAGAC
GATGCAGGCCGGCCGCTGA

Upstream 100 bases:

>100_bases
GGAGCGCTTCCAGATCATCGAACCGGAGCTGAAAGCCGTAGAGACCTTTATCGGCAAACACGCCCGCGGCAAGACGACGG
CAGGCGCAGAAAGATAGCCA

Downstream 100 bases:

>100_bases
GCCGGCGTCCGTCCTGCCGGGAGTGATCGATGCCAAAATCGGTGTTTCGGTTTCTGTCGCGGCAGCCGGATGCGGTCGAG
CTGGAAAACGACAGATATCT

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTVECTRLKSGLTVVTETMPHLESVALGVWIKSGSRNETADEHGIAHLLEHMAFKGTGRRSARQIAEEIEDVGGEVNAAT
STETTSYYARVLKDHVPLAVDILADILTESAFEEEELEREKQVILQEINAANDTPDDVVFDRFSEVAYRDQTLGRAILGT
PETVVSFTPQQIRGYLGRNYTTDRMFVVATGAVEHDEFVRMVEDRFASLPSEPSAPPVMEAARYIGGSVREPRDLMDAQI
LLGFEGKPYHARDFYCSQILANILGGGMSSRLFQEVREFRGLCYSVYAFHWGFSDTGIFGIHAATGGENLPQLVPVIIDE
LHKSADQIHQKEIERARAQIRAQLLMGQESPASRAGQIARQMMLYGRPISNMEMMERLEGITIERLTDLAGRLFYDTVPT
LSAIGPLEQLAPMEDITASLSVPAPKTMQAGR

Sequences:

>Translated_432_residues
MTVECTRLKSGLTVVTETMPHLESVALGVWIKSGSRNETADEHGIAHLLEHMAFKGTGRRSARQIAEEIEDVGGEVNAAT
STETTSYYARVLKDHVPLAVDILADILTESAFEEEELEREKQVILQEINAANDTPDDVVFDRFSEVAYRDQTLGRAILGT
PETVVSFTPQQIRGYLGRNYTTDRMFVVATGAVEHDEFVRMVEDRFASLPSEPSAPPVMEAARYIGGSVREPRDLMDAQI
LLGFEGKPYHARDFYCSQILANILGGGMSSRLFQEVREFRGLCYSVYAFHWGFSDTGIFGIHAATGGENLPQLVPVIIDE
LHKSADQIHQKEIERARAQIRAQLLMGQESPASRAGQIARQMMLYGRPISNMEMMERLEGITIERLTDLAGRLFYDTVPT
LSAIGPLEQLAPMEDITASLSVPAPKTMQAGR
>Mature_431_residues
TVECTRLKSGLTVVTETMPHLESVALGVWIKSGSRNETADEHGIAHLLEHMAFKGTGRRSARQIAEEIEDVGGEVNAATS
TETTSYYARVLKDHVPLAVDILADILTESAFEEEELEREKQVILQEINAANDTPDDVVFDRFSEVAYRDQTLGRAILGTP
ETVVSFTPQQIRGYLGRNYTTDRMFVVATGAVEHDEFVRMVEDRFASLPSEPSAPPVMEAARYIGGSVREPRDLMDAQIL
LGFEGKPYHARDFYCSQILANILGGGMSSRLFQEVREFRGLCYSVYAFHWGFSDTGIFGIHAATGGENLPQLVPVIIDEL
HKSADQIHQKEIERARAQIRAQLLMGQESPASRAGQIARQMMLYGRPISNMEMMERLEGITIERLTDLAGRLFYDTVPTL
SAIGPLEQLAPMEDITASLSVPAPKTMQAGR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=428, Percent_Identity=32.4766355140187, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI46593007, Length=415, Percent_Identity=27.710843373494, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI24308013, Length=448, Percent_Identity=26.5625, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI50592988, Length=417, Percent_Identity=21.5827338129496, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1787770, Length=206, Percent_Identity=28.1553398058252, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367164, Length=220, Percent_Identity=26.3636363636364, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=429, Percent_Identity=29.8368298368298, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17553678, Length=416, Percent_Identity=26.4423076923077, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17510601, Length=454, Percent_Identity=25.3303964757709, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17569737, Length=325, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=426, Percent_Identity=31.924882629108, Blast_Score=233, Evalue=6e-62,
Organism=Saccharomyces cerevisiae, GI6321813, Length=420, Percent_Identity=28.0952380952381, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319426, Length=441, Percent_Identity=21.5419501133787, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325449, Length=309, Percent_Identity=28.1553398058252, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357875, Length=427, Percent_Identity=30.2107728337237, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI24646943, Length=427, Percent_Identity=30.2107728337237, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI19921772, Length=451, Percent_Identity=25.9423503325942, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24665395, Length=397, Percent_Identity=23.1738035264484, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47897; Mature: 47766

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVECTRLKSGLTVVTETMPHLESVALGVWIKSGSRNETADEHGIAHLLEHMAFKGTGRR
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCHH
SARQIAEEIEDVGGEVNAATSTETTSYYARVLKDHVPLAVDILADILTESAFEEEELERE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHH
KQVILQEINAANDTPDDVVFDRFSEVAYRDQTLGRAILGTPETVVSFTPQQIRGYLGRNY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHCCHHHHHHHHCCCC
TTDRMFVVATGAVEHDEFVRMVEDRFASLPSEPSAPPVMEAARYIGGSVREPRDLMDAQI
CCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCHHH
LLGFEGKPYHARDFYCSQILANILGGGMSSRLFQEVREFRGLCYSVYAFHWGFSDTGIFG
EEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IHAATGGENLPQLVPVIIDELHKSADQIHQKEIERARAQIRAQLLMGQESPASRAGQIAR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QMMLYGRPISNMEMMERLEGITIERLTDLAGRLFYDTVPTLSAIGPLEQLAPMEDITASL
HHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCC
SVPAPKTMQAGR
CCCCCCCCCCCC
>Mature Secondary Structure 
TVECTRLKSGLTVVTETMPHLESVALGVWIKSGSRNETADEHGIAHLLEHMAFKGTGRR
CCCHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCHH
SARQIAEEIEDVGGEVNAATSTETTSYYARVLKDHVPLAVDILADILTESAFEEEELERE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHH
KQVILQEINAANDTPDDVVFDRFSEVAYRDQTLGRAILGTPETVVSFTPQQIRGYLGRNY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHCCHHHHHHHHCCCC
TTDRMFVVATGAVEHDEFVRMVEDRFASLPSEPSAPPVMEAARYIGGSVREPRDLMDAQI
CCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCHHH
LLGFEGKPYHARDFYCSQILANILGGGMSSRLFQEVREFRGLCYSVYAFHWGFSDTGIFG
EEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IHAATGGENLPQLVPVIIDELHKSADQIHQKEIERARAQIRAQLLMGQESPASRAGQIAR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QMMLYGRPISNMEMMERLEGITIERLTDLAGRLFYDTVPTLSAIGPLEQLAPMEDITASL
HHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCC
SVPAPKTMQAGR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA