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The map label for this gene is 209548225

Identifier: 209548225

GI number: 209548225

Start: 642325

End: 642810

Strand: Direct

Name: 209548225

Synonym: Rleg2_0619

Alternate gene names: NA

Gene position: 642325-642810 (Clockwise)

Preceding gene: 209548224

Following gene: 209548226

Centisome position: 14.15

GC content: 64.61

Gene sequence:

>486_bases
ATGACCATCGCGATCGGCGACAAGCTTCCTGCCGCCACTTTCAAGGAAAAGACCGCCGACGGCCCGGTCGAAATCACCAC
CGAGCAGCTGTTCTCTGGCAAGCGCGTCGTGCTGTTTGCCGTGCCCGGCGCCTTCACGCCCACCTGCTCGCTGAACCACC
TGCCGGGTTATCTCGAAAACCGCGACACCATCCTCGGCAAGGGCGTCGACGACATCGCTGTCATCGCCGTGAATGACTGG
CACGTGATGGGCGCCTGGGCGCAATCCTCCGGCGGCCTGGGCAAGATCCACTTCCTCGCCGATTGGGACGCCGCTTTCAC
CAAGGCCGTCGGCCTCGACGCCGACCTCTCCGGCGGCGGCCTCGGTCTGCGCTCCAAGCGCTATTCGATGCTGGTGGAAG
ACGGCGTGGTCAAAGCCCTCAACGTCGAGGAAAGCCCTGGCCAGGCCACGGTTTCTGGTGCTGCGGCGATGCTGGAACTG
CTCTGA

Upstream 100 bases:

>100_bases
TTTGACTGACCGGCTCTTATAGTCGCGGCAGAGCCCCTGCGGCGCCCCCCGCCCAGCCGGAATCCCAAAACCCAAAAAAC
CGGAACTCAAGGAGAAGATC

Downstream 100 bases:

>100_bases
GTTTTCATTCCGAGAGATGAAGGGGCGGCCATTCGGTCGCCCTTTTCAATTGTTGTTGCGCCGCTCGTTATGTTGGGAAG
CGCCCTCCTTCCTTTCAGGC

Product: redoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTIAIGDKLPAATFKEKTADGPVEITTEQLFSGKRVVLFAVPGAFTPTCSLNHLPGYLENRDTILGKGVDDIAVIAVNDW
HVMGAWAQSSGGLGKIHFLADWDAAFTKAVGLDADLSGGGLGLRSKRYSMLVEDGVVKALNVEESPGQATVSGAAAMLEL
L

Sequences:

>Translated_161_residues
MTIAIGDKLPAATFKEKTADGPVEITTEQLFSGKRVVLFAVPGAFTPTCSLNHLPGYLENRDTILGKGVDDIAVIAVNDW
HVMGAWAQSSGGLGKIHFLADWDAAFTKAVGLDADLSGGGLGLRSKRYSMLVEDGVVKALNVEESPGQATVSGAAAMLEL
L
>Mature_160_residues
TIAIGDKLPAATFKEKTADGPVEITTEQLFSGKRVVLFAVPGAFTPTCSLNHLPGYLENRDTILGKGVDDIAVIAVNDWH
VMGAWAQSSGGLGKIHFLADWDAAFTKAVGLDADLSGGGLGLRSKRYSMLVEDGVVKALNVEESPGQATVSGAAAMLELL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=143, Percent_Identity=44.7552447552448, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323138, Length=178, Percent_Identity=32.5842696629214, Blast_Score=81, Evalue=9e-17,
Organism=Drosophila melanogaster, GI78706776, Length=143, Percent_Identity=48.2517482517483, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI78709078, Length=143, Percent_Identity=48.2517482517483, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16843; Mature: 16712

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAIGDKLPAATFKEKTADGPVEITTEQLFSGKRVVLFAVPGAFTPTCSLNHLPGYLEN
CEEEECCCCCCCCCCCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCC
RDTILGKGVDDIAVIAVNDWHVMGAWAQSSGGLGKIHFLADWDAAFTKAVGLDADLSGGG
CCEEEECCCCCEEEEEECCEEEEEEEECCCCCEEEEEEEEECCHHHHHHHCCCCCCCCCC
LGLRSKRYSMLVEDGVVKALNVEESPGQATVSGAAAMLELL
CCCCCCHHEEEECCCEEEEEECCCCCCCEEHHHHHHHHHCC
>Mature Secondary Structure 
TIAIGDKLPAATFKEKTADGPVEITTEQLFSGKRVVLFAVPGAFTPTCSLNHLPGYLEN
EEEECCCCCCCCCCCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCC
RDTILGKGVDDIAVIAVNDWHVMGAWAQSSGGLGKIHFLADWDAAFTKAVGLDADLSGGG
CCEEEECCCCCEEEEEECCEEEEEEEECCCCCEEEEEEEEECCHHHHHHHCCCCCCCCCC
LGLRSKRYSMLVEDGVVKALNVEESPGQATVSGAAAMLELL
CCCCCCHHEEEECCCEEEEEECCCCCCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]