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The map label for this gene is thrB [H]

Identifier: 209548218

GI number: 209548218

Start: 636674

End: 637639

Strand: Direct

Name: thrB [H]

Synonym: Rleg2_0612

Alternate gene names: 209548218

Gene position: 636674-637639 (Clockwise)

Preceding gene: 209548217

Following gene: 209548219

Centisome position: 14.03

GC content: 61.9

Gene sequence:

>966_bases
TTGGCAGTCTATACCGATATCGCCGAAGACGATCTGAAGTGGTTCCTGACGGAGTATGACGCCGGCACGCTGCTCTCCTA
CAAAGGCATCGCCGAAGGCGTCGAAAATTCCAATTTCCTGCTGCATACCTCGAAGGATCCGCTGATTCTGACGCTTTATG
AGAAGCGCGTGGAAAAGACCGATCTGCCGTTCTTTCTCGGCCTGATGCAGCATCTTTCCGCCCGCGGTCTTTCCTGCCCG
CTGCCGCTGCCGCGCCGTGACGGCGCGCTGCTCGGCTCGCTCTCCGGCCGCCCGGCGGCGCTGATCTCCTTCCTCGAAGG
CATGTGGCTGCGGAAACCGGAGGCCAAACATTGCCGCGAGGTCGGCCGGGCGCTGGCCGAAATGCATGTCGCCGGCGATG
GTTTTGAACTCAAGCGCCCGAACGCGCTGTCGATCGACGGCTGGCAAACGCTCTGGGAGAAATCCGAGGCGCGCGCCGGC
GAGGTCGAGGCCGGCCTGCAGGACGAGATCCGCGGCGAACTCGATTTCCTCGCCGCCGCCTGGCCGAAAAACCTGCCGGC
CGGCATCATCCACGCCGACCTTTTCCCCGACAACGTCTTCTTCCTCGGTGACGCGCTCTCCGGCCTGATCGATTTCTATT
TCGCCTGCAACGACCTGCTCGCCTATGACGTCTCGATCTGCCTGAACGCCTGGTGCTTCGAAAAGGACGGCGCTTACAAC
ATCACCAAGGGCACAGCGATGCTCGAGGGTTACCAGAGCGTGCGCCCGTTGAGCGGCGAAGAGATTGCCGCTTTGCCGGT
GCTGTCGCGCGGTTCGGCGCTGCGCTTCTTCCTGACGCGGCTCTATGATTGGTTGACGACGCCTGAAGGCGCCATGGTCA
CCAAGAAGGACCCGCTCGAATATCTCCGCAAGCTGCGTTTCCACCGCCAGATCAAATCGCCGGCCGAATACGGATTGAGC
CTATGA

Upstream 100 bases:

>100_bases
TGGCCTTCGTCAACGGCTGATCCCCAGACGGAAATCCTATCGACGCCGGATGGTCGATCCGGTGGCCCAATAACCGCAAT
GCATGAAGGCGAGACCTCAC

Downstream 100 bases:

>100_bases
AACACGTCGATATCTTCACCGACGGCGCCTGCTCCGGCAATCCCGGCCCCGGCGGCTGGGGCGCCGTGCTGCGCTATGGC
GACGTCGAAAAGGAGCTTTG

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAVYTDIAEDDLKWFLTEYDAGTLLSYKGIAEGVENSNFLLHTSKDPLILTLYEKRVEKTDLPFFLGLMQHLSARGLSCP
LPLPRRDGALLGSLSGRPAALISFLEGMWLRKPEAKHCREVGRALAEMHVAGDGFELKRPNALSIDGWQTLWEKSEARAG
EVEAGLQDEIRGELDFLAAAWPKNLPAGIIHADLFPDNVFFLGDALSGLIDFYFACNDLLAYDVSICLNAWCFEKDGAYN
ITKGTAMLEGYQSVRPLSGEEIAALPVLSRGSALRFFLTRLYDWLTTPEGAMVTKKDPLEYLRKLRFHRQIKSPAEYGLS
L

Sequences:

>Translated_321_residues
MAVYTDIAEDDLKWFLTEYDAGTLLSYKGIAEGVENSNFLLHTSKDPLILTLYEKRVEKTDLPFFLGLMQHLSARGLSCP
LPLPRRDGALLGSLSGRPAALISFLEGMWLRKPEAKHCREVGRALAEMHVAGDGFELKRPNALSIDGWQTLWEKSEARAG
EVEAGLQDEIRGELDFLAAAWPKNLPAGIIHADLFPDNVFFLGDALSGLIDFYFACNDLLAYDVSICLNAWCFEKDGAYN
ITKGTAMLEGYQSVRPLSGEEIAALPVLSRGSALRFFLTRLYDWLTTPEGAMVTKKDPLEYLRKLRFHRQIKSPAEYGLS
L
>Mature_320_residues
AVYTDIAEDDLKWFLTEYDAGTLLSYKGIAEGVENSNFLLHTSKDPLILTLYEKRVEKTDLPFFLGLMQHLSARGLSCPL
PLPRRDGALLGSLSGRPAALISFLEGMWLRKPEAKHCREVGRALAEMHVAGDGFELKRPNALSIDGWQTLWEKSEARAGE
VEAGLQDEIRGELDFLAAAWPKNLPAGIIHADLFPDNVFFLGDALSGLIDFYFACNDLLAYDVSICLNAWCFEKDGAYNI
TKGTAMLEGYQSVRPLSGEEIAALPVLSRGSALRFFLTRLYDWLTTPEGAMVTKKDPLEYLRKLRFHRQIKSPAEYGLSL

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 35826; Mature: 35695

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDIAEDDLKWFLTEYDAGTLLSYKGIAEGVENSNFLLHTSKDPLILTLYEKRVEKT
CCEECCCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHC
DLPFFLGLMQHLSARGLSCPLPLPRRDGALLGSLSGRPAALISFLEGMWLRKPEAKHCRE
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHH
VGRALAEMHVAGDGFELKRPNALSIDGWQTLWEKSEARAGEVEAGLQDEIRGELDFLAAA
HHHHHHHHHHCCCCEEECCCCEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
WPKNLPAGIIHADLFPDNVFFLGDALSGLIDFYFACNDLLAYDVSICLNAWCFEKDGAYN
CCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEE
ITKGTAMLEGYQSVRPLSGEEIAALPVLSRGSALRFFLTRLYDWLTTPEGAMVTKKDPLE
ECCCHHHHHHHHHCCCCCCCCEEECEECCCCCHHHHHHHHHHHHHCCCCCCEECCCCHHH
YLRKLRFHRQIKSPAEYGLSL
HHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure 
AVYTDIAEDDLKWFLTEYDAGTLLSYKGIAEGVENSNFLLHTSKDPLILTLYEKRVEKT
CEECCCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHC
DLPFFLGLMQHLSARGLSCPLPLPRRDGALLGSLSGRPAALISFLEGMWLRKPEAKHCRE
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHH
VGRALAEMHVAGDGFELKRPNALSIDGWQTLWEKSEARAGEVEAGLQDEIRGELDFLAAA
HHHHHHHHHHCCCCEEECCCCEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
WPKNLPAGIIHADLFPDNVFFLGDALSGLIDFYFACNDLLAYDVSICLNAWCFEKDGAYN
CCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEE
ITKGTAMLEGYQSVRPLSGEEIAALPVLSRGSALRFFLTRLYDWLTTPEGAMVTKKDPLE
ECCCHHHHHHHHHCCCCCCCCEEECEECCCCCHHHHHHHHHHHHHCCCCCCEECCCCHHH
YLRKLRFHRQIKSPAEYGLSL
HHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA