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The map label for this gene is pdxH [H]

Identifier: 209548200

GI number: 209548200

Start: 620466

End: 621086

Strand: Direct

Name: pdxH [H]

Synonym: Rleg2_0594

Alternate gene names: 209548200

Gene position: 620466-621086 (Clockwise)

Preceding gene: 209548195

Following gene: 209548202

Centisome position: 13.67

GC content: 60.06

Gene sequence:

>621_bases
ATGTCGGCAAACGAGTTAACAAGCGGTGACTTTACCGAAAGTGGCGAACCCTTCAAGCTCTTTGCCGAATGGCTTGGCGA
AGCGGAGGCTTCCGAACCCAACGACCCGAACGCCGTGGCGCTGGCAACGGTCGACGAGGATGGTCTTCCCAATGTCCGCA
TGGTTCTCCTGAAGGGATTCGACGACAACGGTTTCGTCTTCTACACCAATTTCGAGAGCCAGAAAGGCCGTGAAATTCTG
GGCCAGAAAAAGGCAGCCATGTGCTTTCACTGGAAAAGCCTGCGCCGCCAGGTCAGGTTGCGCGGCCCGGTCGAGATCGT
CACCGATGCCGAGGCCGACGCCTATTTCAAGACCCGGGCCCGCGGCAGTCGCATCGGCGCCTGGGCCTCGAAACAATCCC
GCCCGCTCGAAAGCCGTTTCGCGCTGGAGAAGGCCGTGGCCGAATATACCGCCCGTTATGCCATCGGCGAAATTCCGCGC
CCCGCCCATTGGTCGGGCTTCCGCATCCGGCCGACCTCGATCGAATTCTGGAAGGACCAGAACTTCCGTCTGCATGACCG
CATCGAATTTCGCCGGCCGTTGCCGGAAGGCGCATGGGACAAGGTCAGGATGTATCCGTAA

Upstream 100 bases:

>100_bases
TTTGTATGGCGATATGACTTTGCTATGACTTCCACCCTGCATCCTGTCCAGTTATCAAAAGCTGGGCGAGTTTTGAATAA
TCCGGGGCATTTGAACCAAT

Downstream 100 bases:

>100_bases
ACGGCCCTATTTGCCCATCAGCTTCAGCGGAATGCCGGAGGCAAGCGCCGAGACGTAGCGTCGCTTCTGGTAGAAACCGT
TCAGCGAAATGCGCGAGAGA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSANELTSGDFTESGEPFKLFAEWLGEAEASEPNDPNAVALATVDEDGLPNVRMVLLKGFDDNGFVFYTNFESQKGREIL
GQKKAAMCFHWKSLRRQVRLRGPVEIVTDAEADAYFKTRARGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPR
PAHWSGFRIRPTSIEFWKDQNFRLHDRIEFRRPLPEGAWDKVRMYP

Sequences:

>Translated_206_residues
MSANELTSGDFTESGEPFKLFAEWLGEAEASEPNDPNAVALATVDEDGLPNVRMVLLKGFDDNGFVFYTNFESQKGREIL
GQKKAAMCFHWKSLRRQVRLRGPVEIVTDAEADAYFKTRARGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPR
PAHWSGFRIRPTSIEFWKDQNFRLHDRIEFRRPLPEGAWDKVRMYP
>Mature_205_residues
SANELTSGDFTESGEPFKLFAEWLGEAEASEPNDPNAVALATVDEDGLPNVRMVLLKGFDDNGFVFYTNFESQKGREILG
QKKAAMCFHWKSLRRQVRLRGPVEIVTDAEADAYFKTRARGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPRP
AHWSGFRIRPTSIEFWKDQNFRLHDRIEFRRPLPEGAWDKVRMYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=185, Percent_Identity=45.4054054054054, Blast_Score=164, Evalue=5e-41,
Organism=Escherichia coli, GI1787926, Length=192, Percent_Identity=41.1458333333333, Blast_Score=157, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17553712, Length=200, Percent_Identity=39.5, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319509, Length=197, Percent_Identity=39.5939086294416, Blast_Score=139, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45551845, Length=185, Percent_Identity=42.1621621621622, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24644901, Length=185, Percent_Identity=42.1621621621622, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24644903, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23606; Mature: 23475

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANELTSGDFTESGEPFKLFAEWLGEAEASEPNDPNAVALATVDEDGLPNVRMVLLKGF
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECC
DDNGFVFYTNFESQKGREILGQKKAAMCFHWKSLRRQVRLRGPVEIVTDAEADAYFKTRA
CCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHC
RGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPRPAHWSGFRIRPTSIEFWKDQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECCC
NFRLHDRIEFRRPLPEGAWDKVRMYP
CCEEECHHHHCCCCCCCCCCCEEECC
>Mature Secondary Structure 
SANELTSGDFTESGEPFKLFAEWLGEAEASEPNDPNAVALATVDEDGLPNVRMVLLKGF
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECC
DDNGFVFYTNFESQKGREILGQKKAAMCFHWKSLRRQVRLRGPVEIVTDAEADAYFKTRA
CCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHC
RGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPRPAHWSGFRIRPTSIEFWKDQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECCC
NFRLHDRIEFRRPLPEGAWDKVRMYP
CCEEECHHHHCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA