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The map label for this gene is mcpA [H]

Identifier: 209548143

GI number: 209548143

Start: 551894

End: 553711

Strand: Direct

Name: mcpA [H]

Synonym: Rleg2_0537

Alternate gene names: 209548143

Gene position: 551894-553711 (Clockwise)

Preceding gene: 209548142

Following gene: 209548145

Centisome position: 12.16

GC content: 62.6

Gene sequence:

>1818_bases
ATGAAAAATCTGAAAATATCGAAGCAGCTCATATTGCTGGTCGTCGGCCTGATGATCGCCTTCGCGGTCGCCACATCCCT
GCAGATCCGCTCGTCCGTCGATGCGATCTATAAGGAGCGTTATGACATGCTCCGCGCCGAGGTTCAGTCGGCGGTCTCCG
TTCTCAAGCTTTACCAGGCCAAGGTCACCGCGGGCGAAATGACGCTCGAAGAGGCGCAGAAGCAGGCCTACGCCACCGTC
AACGCGATGAAATACGATCCCGATGGCTATTTCTTCGGCTATAGCTACGACATCCAGATGATGTTCCACTTTGATGCCTC
TAAAATCGGGCAGGTCAACAAGGGGCAGCCGGACAGCAAAGGCAAGCTCTATCGCGAAGAGCTGGTCAGGCTCGGGCAGC
AGGGCGGCGGTCTCGTCGAATATTATTCCACAGCCAAACCCGGCCAGCCGGCCGGCGATTTTCGCAAGACGGCCTATGCA
CAGGCCTTCGACCCTTGGAAGGTCGTCGTCGTCACCGGCGTCTACATGGAGGATCTCGATGCCCAGATCAACAGCACGAT
CCTGACCGCCCTGTCCGGCAGCATCATACTGTTCTTCCTGGCTATTGCGGCCGCTTATCTCGTCATCCGCGGCATTTCCG
GCCCTCTCAACAACGTCCATGCAGCCCTGAAGGCGGTAGCCGAAGAAGACGTTTCCATCGCCATTCCGCATGCCGGCATG
AACAACGAAGTCGGGATGATGGCCAAGGCGACGCAGTCGCTGCAGGAAAAGATCCGCGAACGCCATGCCATGTCGGATCG
CGAGGCGGCCCAGCAGCTGGCGCTGGAAAACGAGCGCGAAAACAATCAGCGCCAGCAGCAGGACGAGACGGCTCTCCAGG
CCCGCGTGGTGGCGACCATCGGCCAGGCGCTGGAGATGATCGCCCGCGGCGATCTGACTGTCCGCTGCGCCGATCTCGGC
CAGAAATATGCCGCCCTGCGCGACAACTTCAACGATGCGCTGTCGCATCTCGAAGCCGCCATGGCCAAGGTCAGCGCCAA
GGGCACCGATATCGGCACCAGCAAGGAAGAAATCCGCCGCGCCTCCAACGAGCTGTCGCAGCGCACTGAGCGCCAGGCGG
CAAGCCTCGAGGAAACCTCGGCAGCCCTCGACGAACTCACCGTCGCCGTCCGCCAGACGGCCGATGGCGCCCATGAGGCG
AGCAAACGCGTCCACTCGGTCAGCAACGAGGCCACCCACAGCGATGCGATCGTCGGCCAGGCGATCGAGGCGATGAGCGG
CATCGAGAAGTCATCGTCGGAAATTACCAAGATCATCGGCGTCATCGACGAGATCGCCTTCCAGACCAACCTCCTGGCGC
TGAATGCCGGCGTCGAGGCTGCCCGCGCCGGTGAATCCGGCAAGGGGTTTGCGGTCGTCGCCCAGGAAGTGCGCGAACTC
GCCCAGCGCTCCGCCGCCGCGGCCAAGGAGATCAAGGACCAGATCGCCCGCTCCTCCAGCCAGGTCGAGCACGGCGTCCG
CCTGGTCGGCGAGGCAGGCGAGGCGCTGAAGCGCATCTCAGACCAGATCAAGGCCGCCAACGAGATCGTCGCCAAGATCG
CCCACAGCGCCTCCGAGCAGGACACGACACTGCGCTCGATCTCATCGTCGATGAACCAGCTCGACGCCGCCACCCAGCAG
AACGCCGCCATGGCCGAGGAAACCACGGCTTCGGCCGAAACGCTTGCCAGCGACACCGACGAGTTGATTGATCTGATCCG
CGGCTTCCGCGTCAGTGCCGCTGCGCCTGCCCTGCATCAGGGACGCCGCGCCGCTTAA

Upstream 100 bases:

>100_bases
GTTGTTTGAGCAGCGGTAGATGCGTCGCCGTTTTGGCGCGCTCGCACAGGCGGTAGGAAACCGCACCGGACTGCACACAC
CGTTCCCGTTGCGAGGCGTC

Downstream 100 bases:

>100_bases
ACGGCGTCGGGACGACAGGCGTTTTTATCACCCAACAACACGGCCGTCGGTTCTCCGGCGGCCGTGTTGTTTTGGAAGGC
GGCCGCAGCCAACAAATCAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MKNLKISKQLILLVVGLMIAFAVATSLQIRSSVDAIYKERYDMLRAEVQSAVSVLKLYQAKVTAGEMTLEEAQKQAYATV
NAMKYDPDGYFFGYSYDIQMMFHFDASKIGQVNKGQPDSKGKLYREELVRLGQQGGGLVEYYSTAKPGQPAGDFRKTAYA
QAFDPWKVVVVTGVYMEDLDAQINSTILTALSGSIILFFLAIAAAYLVIRGISGPLNNVHAALKAVAEEDVSIAIPHAGM
NNEVGMMAKATQSLQEKIRERHAMSDREAAQQLALENERENNQRQQQDETALQARVVATIGQALEMIARGDLTVRCADLG
QKYAALRDNFNDALSHLEAAMAKVSAKGTDIGTSKEEIRRASNELSQRTERQAASLEETSAALDELTVAVRQTADGAHEA
SKRVHSVSNEATHSDAIVGQAIEAMSGIEKSSSEITKIIGVIDEIAFQTNLLALNAGVEAARAGESGKGFAVVAQEVREL
AQRSAAAAKEIKDQIARSSSQVEHGVRLVGEAGEALKRISDQIKAANEIVAKIAHSASEQDTTLRSISSSMNQLDAATQQ
NAAMAEETTASAETLASDTDELIDLIRGFRVSAAAPALHQGRRAA

Sequences:

>Translated_605_residues
MKNLKISKQLILLVVGLMIAFAVATSLQIRSSVDAIYKERYDMLRAEVQSAVSVLKLYQAKVTAGEMTLEEAQKQAYATV
NAMKYDPDGYFFGYSYDIQMMFHFDASKIGQVNKGQPDSKGKLYREELVRLGQQGGGLVEYYSTAKPGQPAGDFRKTAYA
QAFDPWKVVVVTGVYMEDLDAQINSTILTALSGSIILFFLAIAAAYLVIRGISGPLNNVHAALKAVAEEDVSIAIPHAGM
NNEVGMMAKATQSLQEKIRERHAMSDREAAQQLALENERENNQRQQQDETALQARVVATIGQALEMIARGDLTVRCADLG
QKYAALRDNFNDALSHLEAAMAKVSAKGTDIGTSKEEIRRASNELSQRTERQAASLEETSAALDELTVAVRQTADGAHEA
SKRVHSVSNEATHSDAIVGQAIEAMSGIEKSSSEITKIIGVIDEIAFQTNLLALNAGVEAARAGESGKGFAVVAQEVREL
AQRSAAAAKEIKDQIARSSSQVEHGVRLVGEAGEALKRISDQIKAANEIVAKIAHSASEQDTTLRSISSSMNQLDAATQQ
NAAMAEETTASAETLASDTDELIDLIRGFRVSAAAPALHQGRRAA
>Mature_605_residues
MKNLKISKQLILLVVGLMIAFAVATSLQIRSSVDAIYKERYDMLRAEVQSAVSVLKLYQAKVTAGEMTLEEAQKQAYATV
NAMKYDPDGYFFGYSYDIQMMFHFDASKIGQVNKGQPDSKGKLYREELVRLGQQGGGLVEYYSTAKPGQPAGDFRKTAYA
QAFDPWKVVVVTGVYMEDLDAQINSTILTALSGSIILFFLAIAAAYLVIRGISGPLNNVHAALKAVAEEDVSIAIPHAGM
NNEVGMMAKATQSLQEKIRERHAMSDREAAQQLALENERENNQRQQQDETALQARVVATIGQALEMIARGDLTVRCADLG
QKYAALRDNFNDALSHLEAAMAKVSAKGTDIGTSKEEIRRASNELSQRTERQAASLEETSAALDELTVAVRQTADGAHEA
SKRVHSVSNEATHSDAIVGQAIEAMSGIEKSSSEITKIIGVIDEIAFQTNLLALNAGVEAARAGESGKGFAVVAQEVREL
AQRSAAAAKEIKDQIARSSSQVEHGVRLVGEAGEALKRISDQIKAANEIVAKIAHSASEQDTTLRSISSSMNQLDAATQQ
NAAMAEETTASAETLASDTDELIDLIRGFRVSAAAPALHQGRRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=280, Percent_Identity=42.1428571428571, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1787690, Length=300, Percent_Identity=40, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1788194, Length=305, Percent_Identity=39.0163934426229, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI2367378, Length=264, Percent_Identity=42.8030303030303, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789453, Length=286, Percent_Identity=36.3636363636364, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65196; Mature: 65196

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLKISKQLILLVVGLMIAFAVATSLQIRSSVDAIYKERYDMLRAEVQSAVSVLKLYQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVTAGEMTLEEAQKQAYATVNAMKYDPDGYFFGYSYDIQMMFHFDASKIGQVNKGQPDSK
HHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEEEEEEEECHHHCCCCCCCCCCCC
GKLYREELVRLGQQGGGLVEYYSTAKPGQPAGDFRKTAYAQAFDPWKVVVVTGVYMEDLD
CHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHH
AQINSTILTALSGSIILFFLAIAAAYLVIRGISGPLNNVHAALKAVAEEDVSIAIPHAGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
NNEVGMMAKATQSLQEKIRERHAMSDREAAQQLALENERENNQRQQQDETALQARVVATI
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQALEMIARGDLTVRCADLGQKYAALRDNFNDALSHLEAAMAKVSAKGTDIGTSKEEIRR
HHHHHHHHCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ASNELSQRTERQAASLEETSAALDELTVAVRQTADGAHEASKRVHSVSNEATHSDAIVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
AIEAMSGIEKSSSEITKIIGVIDEIAFQTNLLALNAGVEAARAGESGKGFAVVAQEVREL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAAAAKEIKDQIARSSSQVEHGVRLVGEAGEALKRISDQIKAANEIVAKIAHSASEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DTTLRSISSSMNQLDAATQQNAAMAEETTASAETLASDTDELIDLIRGFRVSAAAPALHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCHHHHC
GRRAA
CCCCC
>Mature Secondary Structure
MKNLKISKQLILLVVGLMIAFAVATSLQIRSSVDAIYKERYDMLRAEVQSAVSVLKLYQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVTAGEMTLEEAQKQAYATVNAMKYDPDGYFFGYSYDIQMMFHFDASKIGQVNKGQPDSK
HHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEEEEEEEECHHHCCCCCCCCCCCC
GKLYREELVRLGQQGGGLVEYYSTAKPGQPAGDFRKTAYAQAFDPWKVVVVTGVYMEDLD
CHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHH
AQINSTILTALSGSIILFFLAIAAAYLVIRGISGPLNNVHAALKAVAEEDVSIAIPHAGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
NNEVGMMAKATQSLQEKIRERHAMSDREAAQQLALENERENNQRQQQDETALQARVVATI
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQALEMIARGDLTVRCADLGQKYAALRDNFNDALSHLEAAMAKVSAKGTDIGTSKEEIRR
HHHHHHHHCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ASNELSQRTERQAASLEETSAALDELTVAVRQTADGAHEASKRVHSVSNEATHSDAIVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHH
AIEAMSGIEKSSSEITKIIGVIDEIAFQTNLLALNAGVEAARAGESGKGFAVVAQEVREL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAAAAKEIKDQIARSSSQVEHGVRLVGEAGEALKRISDQIKAANEIVAKIAHSASEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DTTLRSISSSMNQLDAATQQNAAMAEETTASAETLASDTDELIDLIRGFRVSAAAPALHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCHHHHC
GRRAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]