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The map label for this gene is yajO [H]

Identifier: 209548067

GI number: 209548067

Start: 470909

End: 471958

Strand: Direct

Name: yajO [H]

Synonym: Rleg2_0460

Alternate gene names: 209548067

Gene position: 470909-471958 (Clockwise)

Preceding gene: 209548065

Following gene: 209548071

Centisome position: 10.38

GC content: 64.19

Gene sequence:

>1050_bases
ATGCGTTACAATCAACTCGGAAATACGGGACTTTTCGTCTCGGAAATCTGCCTGGGTACCATGACCTTCGGCGAAGCCAA
ACAGGGCACCATGTGGGGCGCCATCGCCGATGTCGACCAGAATGCCGCCGACCGGATCGTCGAGCGCTCGCTTGCCTCTG
GTGTCAATTTCATCGACACCGCCGATGTCTACTCCGCCGGTGAGTCTGAAAGGCTGCTCGGCCAGGCGCTGAAGAACCTC
GATGTGCCCCGCAAGGACGTCGTCATCGCCACCAAGGTCTATGGCGTCATGGGCGACAAGCCGAATGACCGCGGCGCCTC
GCGCGGCCACATCATGGATTCGGTCGAGGCGAGCCTGAAGCGTCTGCAGACCGATCATATCGACCTCTATCAGATCCACG
CGACCGATACGGTGACGCCGATCGAGGAGACGCTGCGCGCCTTCGACGATCTCGTGTCCCGCGGCCTCGTGCGTTACATC
GGCGTCTCCAACTGGCAGGCCTGGCGCATTTCCAAGGCGCTCGGCCTCTCCGAACGCCGTGGCTTTGCCCGTTTCGAGAC
GGTGCAGGCCTATTATTCCATCGCCGGCCGCGATCTCGAACGCGACATCGTGCCGATGATGCAGGAGGAGAAGCTCGGCC
TGATGGTCTGGTCGCCGCTCGCCGGCGGTCTCCTGTCCGGCAAATACGGTCCCGGCGCGCCCGGCAACGGCGAGGGCCGC
CGCGCCAGTTTCGACTTCCCGCCCGTCGACAAGGACAAGGCCTGGGCCTGCGTCGCCGTCATGCGCGAGGTCGCCGAAAA
GCACGGCGTCAGCGTCGCCACCGTGGCGCTCGCTTACATCCTCGCCAAGCCTTTCGTCACCACGGTGATCATCGGCGCCA
AGCATGTCGACCAGCTCGACCAGAACCTGGCCGCCGTCAAGCTGAAGCTCGATGGGGACGATATGACGAAGCTCGACGAG
GTCAGCGCCCTTGCCCCCGAATATCCGGGCTGGATGCTATCGCGACAGGGCGCCGGCCGCCGGCCGGTCGATTTCGAGCC
GAAGGGCTGA

Upstream 100 bases:

>100_bases
CCACGGCTGTGCCTGTCACGCGCGCAGGCCAATAATCAAAAAATGAAGTTCTTAGGTTCGCAAGCCCCTCTTGCGGCAGA
CACAAAGGATTTTTTCGACC

Downstream 100 bases:

>100_bases
GATCGCTGAGAACAGCCCCTCATCCGCCTGCCGGCACCTTCTCCCCGCGCGCGGGGCGAAGAGACGACGCCGCGACCTCT
CGGTCTCTCGCCAATGTCTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MRYNQLGNTGLFVSEICLGTMTFGEAKQGTMWGAIADVDQNAADRIVERSLASGVNFIDTADVYSAGESERLLGQALKNL
DVPRKDVVIATKVYGVMGDKPNDRGASRGHIMDSVEASLKRLQTDHIDLYQIHATDTVTPIEETLRAFDDLVSRGLVRYI
GVSNWQAWRISKALGLSERRGFARFETVQAYYSIAGRDLERDIVPMMQEEKLGLMVWSPLAGGLLSGKYGPGAPGNGEGR
RASFDFPPVDKDKAWACVAVMREVAEKHGVSVATVALAYILAKPFVTTVIIGAKHVDQLDQNLAAVKLKLDGDDMTKLDE
VSALAPEYPGWMLSRQGAGRRPVDFEPKG

Sequences:

>Translated_349_residues
MRYNQLGNTGLFVSEICLGTMTFGEAKQGTMWGAIADVDQNAADRIVERSLASGVNFIDTADVYSAGESERLLGQALKNL
DVPRKDVVIATKVYGVMGDKPNDRGASRGHIMDSVEASLKRLQTDHIDLYQIHATDTVTPIEETLRAFDDLVSRGLVRYI
GVSNWQAWRISKALGLSERRGFARFETVQAYYSIAGRDLERDIVPMMQEEKLGLMVWSPLAGGLLSGKYGPGAPGNGEGR
RASFDFPPVDKDKAWACVAVMREVAEKHGVSVATVALAYILAKPFVTTVIIGAKHVDQLDQNLAAVKLKLDGDDMTKLDE
VSALAPEYPGWMLSRQGAGRRPVDFEPKG
>Mature_349_residues
MRYNQLGNTGLFVSEICLGTMTFGEAKQGTMWGAIADVDQNAADRIVERSLASGVNFIDTADVYSAGESERLLGQALKNL
DVPRKDVVIATKVYGVMGDKPNDRGASRGHIMDSVEASLKRLQTDHIDLYQIHATDTVTPIEETLRAFDDLVSRGLVRYI
GVSNWQAWRISKALGLSERRGFARFETVQAYYSIAGRDLERDIVPMMQEEKLGLMVWSPLAGGLLSGKYGPGAPGNGEGR
RASFDFPPVDKDKAWACVAVMREVAEKHGVSVATVALAYILAKPFVTTVIIGAKHVDQLDQNLAAVKLKLDGDDMTKLDE
VSALAPEYPGWMLSRQGAGRRPVDFEPKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=333, Percent_Identity=33.033033033033, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI27436962, Length=333, Percent_Identity=33.033033033033, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI27436969, Length=338, Percent_Identity=32.5443786982249, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=32.7327327327327, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4504825, Length=336, Percent_Identity=32.4404761904762, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI27436971, Length=315, Percent_Identity=30.7936507936508, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI223718702, Length=312, Percent_Identity=30.4487179487179, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI41152114, Length=312, Percent_Identity=31.0897435897436, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI41327764, Length=284, Percent_Identity=31.3380281690141, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI223718708, Length=165, Percent_Identity=32.7272727272727, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=38.75, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=31.6239316239316, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=30, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=28.7128712871287, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI48994888, Length=275, Percent_Identity=29.0909090909091, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786400, Length=268, Percent_Identity=26.4925373134328, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082198, Length=285, Percent_Identity=25.2631578947368, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=311, Percent_Identity=28.9389067524116, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17550248, Length=292, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=31.5634218289086, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=31.306990881459, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=31.25, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=331, Percent_Identity=29.9093655589124, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=31.3725490196078, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=32.6923076923077, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24640980, Length=356, Percent_Identity=27.5280898876405, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45549126, Length=356, Percent_Identity=27.5280898876405, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24646159, Length=316, Percent_Identity=31.3291139240506, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646155, Length=314, Percent_Identity=34.0764331210191, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24644950, Length=297, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38121; Mature: 38121

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYNQLGNTGLFVSEICLGTMTFGEAKQGTMWGAIADVDQNAADRIVERSLASGVNFIDT
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHCCCCHHHHHHHHHHHHCCCCCCCC
ADVYSAGESERLLGQALKNLDVPRKDVVIATKVYGVMGDKPNDRGASRGHIMDSVEASLK
HHHHCCCCHHHHHHHHHHHCCCCCHHEEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHH
RLQTDHIDLYQIHATDTVTPIEETLRAFDDLVSRGLVRYIGVSNWQAWRISKALGLSERR
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHC
GFARFETVQAYYSIAGRDLERDIVPMMQEEKLGLMVWSPLAGGLLSGKYGPGAPGNGEGR
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCHHCCHHCCCCCCCCCCCCCCC
RASFDFPPVDKDKAWACVAVMREVAEKHGVSVATVALAYILAKPFVTTVIIGAKHVDQLD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNLAAVKLKLDGDDMTKLDEVSALAPEYPGWMLSRQGAGRRPVDFEPKG
CCEEEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRYNQLGNTGLFVSEICLGTMTFGEAKQGTMWGAIADVDQNAADRIVERSLASGVNFIDT
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHCCCCHHHHHHHHHHHHCCCCCCCC
ADVYSAGESERLLGQALKNLDVPRKDVVIATKVYGVMGDKPNDRGASRGHIMDSVEASLK
HHHHCCCCHHHHHHHHHHHCCCCCHHEEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHH
RLQTDHIDLYQIHATDTVTPIEETLRAFDDLVSRGLVRYIGVSNWQAWRISKALGLSERR
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHC
GFARFETVQAYYSIAGRDLERDIVPMMQEEKLGLMVWSPLAGGLLSGKYGPGAPGNGEGR
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCHHCCHHCCCCCCCCCCCCCCC
RASFDFPPVDKDKAWACVAVMREVAEKHGVSVATVALAYILAKPFVTTVIIGAKHVDQLD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNLAAVKLKLDGDDMTKLDEVSALAPEYPGWMLSRQGAGRRPVDFEPKG
CCEEEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]