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The map label for this gene is frk [H]

Identifier: 209547746

GI number: 209547746

Start: 126825

End: 127751

Strand: Direct

Name: frk [H]

Synonym: Rleg2_0135

Alternate gene names: 209547746

Gene position: 126825-127751 (Clockwise)

Preceding gene: 209547745

Following gene: 209547750

Centisome position: 2.79

GC content: 64.94

Gene sequence:

>927_bases
ATGATTTTGTGCTGCGGCGAAGCCTTGATCGACATGCTGCCGAGGGACACCACCCTGGGCGAAAAGGGCTTTGCGCCCTA
TGCCGGCGGCGCGATTTTCAATACCGCCATCGCGCTTGGCCGCCTCGGCATTCCCACCGCCTTCTTCACCGGTATTGCCG
ACGACATGATGGGCGAAATCCTGCTTGCGACACTGAAGGCGAGCAATGTCGACTACAGCCCCTGCGCCATCACGCAGCGG
CCCTCGACGATCGCTTTCGTCAAACTCGTCAACGGCCAGGCGACCTATGCCTTCTACGACGAGGGCACGGCCGGCCGGAT
GATCACCGAGGCCGACCTGCCTGATCTTGGCGATGATTGCGAAGCGCTGCATTTCGGCGCCATCAGCCTGATCCCGAGCC
CCTGCGGCGAAACCTATGAAGCGCTGCTCGACCGTGAGGCCGAAAAGCGCGTCATCTCGCTCGACCCCAACATCCGCCCC
GGCTTCATCAAGGACAAGCCGGCGCACATGGCCCGCATCAAGCGCATGGCGGCCAAATCCGACATCGTCAAATTCTCCGA
CGAGGATCTCGACTGGTTCGGTCTCGCGGGCGACCATGACGCGCTCGCCGCCCATTGGCTCGCCCACGGCGCCAAACTCG
TCGTCATCACCAAGGGCGCCGAAGGCGCCTCCGGTTATACCAGGGAGCGTAAGGTGACGGTGCCGAGCGAACGCGTCACG
GTCGTCGACACCGTCGGCGCCGGCGACACTTTCGATGCCGGCGTCCTGGCGTCCCTGAAGATGGACGGCCTGCTGACCAA
GCCGCAAGTCGCCGCGCTCGACGAACAGGCGGTGCGCAACGCCCTGACGCTCGGCGCCAAAGCCGCCGCCGTCACCGTCT
CCCGCGCCGGCGCCAACCCGCCCTGGGCGCATGAGATCGGGCTTTAA

Upstream 100 bases:

>100_bases
CGGGACTCAATGGCGGCGTCAGTGAGCTTTCGCTCTAATCGGTTGACAAAAGCTCGCTTAATCGGTTGATGAACATATCA
GTGCTGTTGGGAGAAATTCG

Downstream 100 bases:

>100_bases
GGCTTAAGCCAGCGTCGGCCCCAGCCGTGAGCTCCCGGCCCCTCATCCGCCTGCCGGCACCTTCTCCCCGCGCGCGGGGC
GAAGGGATATGCCGCAGCCT

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MILCCGEALIDMLPRDTTLGEKGFAPYAGGAIFNTAIALGRLGIPTAFFTGIADDMMGEILLATLKASNVDYSPCAITQR
PSTIAFVKLVNGQATYAFYDEGTAGRMITEADLPDLGDDCEALHFGAISLIPSPCGETYEALLDREAEKRVISLDPNIRP
GFIKDKPAHMARIKRMAAKSDIVKFSDEDLDWFGLAGDHDALAAHWLAHGAKLVVITKGAEGASGYTRERKVTVPSERVT
VVDTVGAGDTFDAGVLASLKMDGLLTKPQVAALDEQAVRNALTLGAKAAAVTVSRAGANPPWAHEIGL

Sequences:

>Translated_308_residues
MILCCGEALIDMLPRDTTLGEKGFAPYAGGAIFNTAIALGRLGIPTAFFTGIADDMMGEILLATLKASNVDYSPCAITQR
PSTIAFVKLVNGQATYAFYDEGTAGRMITEADLPDLGDDCEALHFGAISLIPSPCGETYEALLDREAEKRVISLDPNIRP
GFIKDKPAHMARIKRMAAKSDIVKFSDEDLDWFGLAGDHDALAAHWLAHGAKLVVITKGAEGASGYTRERKVTVPSERVT
VVDTVGAGDTFDAGVLASLKMDGLLTKPQVAALDEQAVRNALTLGAKAAAVTVSRAGANPPWAHEIGL
>Mature_308_residues
MILCCGEALIDMLPRDTTLGEKGFAPYAGGAIFNTAIALGRLGIPTAFFTGIADDMMGEILLATLKASNVDYSPCAITQR
PSTIAFVKLVNGQATYAFYDEGTAGRMITEADLPDLGDDCEALHFGAISLIPSPCGETYEALLDREAEKRVISLDPNIRP
GFIKDKPAHMARIKRMAAKSDIVKFSDEDLDWFGLAGDHDALAAHWLAHGAKLVVITKGAEGASGYTRERKVTVPSERVT
VVDTVGAGDTFDAGVLASLKMDGLLTKPQVAALDEQAVRNALTLGAKAAAVTVSRAGANPPWAHEIGL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1790193, Length=285, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 32576; Mature: 32576

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILCCGEALIDMLPRDTTLGEKGFAPYAGGAIFNTAIALGRLGIPTAFFTGIADDMMGEI
CEEECCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LLATLKASNVDYSPCAITQRPSTIAFVKLVNGQATYAFYDEGTAGRMITEADLPDLGDDC
HHHHHHHCCCCCCCEEECCCCCEEEEEEEECCCEEEEEECCCCCCCEEEECCCCCCCCCC
EALHFGAISLIPSPCGETYEALLDREAEKRVISLDPNIRPGFIKDKPAHMARIKRMAAKS
CCEECCEEEECCCCCCHHHHHHHCCHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
DIVKFSDEDLDWFGLAGDHDALAAHWLAHGAKLVVITKGAEGASGYTRERKVTVPSERVT
HHEEECCCCCCEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEECCCCCEE
VVDTVGAGDTFDAGVLASLKMDGLLTKPQVAALDEQAVRNALTLGAKAAAVTVSRAGANP
EEEECCCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
PWAHEIGL
CCHHCCCC
>Mature Secondary Structure
MILCCGEALIDMLPRDTTLGEKGFAPYAGGAIFNTAIALGRLGIPTAFFTGIADDMMGEI
CEEECCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LLATLKASNVDYSPCAITQRPSTIAFVKLVNGQATYAFYDEGTAGRMITEADLPDLGDDC
HHHHHHHCCCCCCCEEECCCCCEEEEEEEECCCEEEEEECCCCCCCEEEECCCCCCCCCC
EALHFGAISLIPSPCGETYEALLDREAEKRVISLDPNIRPGFIKDKPAHMARIKRMAAKS
CCEECCEEEECCCCCCHHHHHHHCCHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
DIVKFSDEDLDWFGLAGDHDALAAHWLAHGAKLVVITKGAEGASGYTRERKVTVPSERVT
HHEEECCCCCCEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEECCCCCEE
VVDTVGAGDTFDAGVLASLKMDGLLTKPQVAALDEQAVRNALTLGAKAAAVTVSRAGANP
EEEECCCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
PWAHEIGL
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8932706 [H]