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The map label for this gene is yggV [C]

Identifier: 209547616

GI number: 209547616

Start: 4696

End: 5340

Strand: Reverse

Name: yggV [C]

Synonym: Rleg2_0004

Alternate gene names: 209547616

Gene position: 5340-4696 (Counterclockwise)

Preceding gene: 209547617

Following gene: 209547615

Centisome position: 0.12

GC content: 63.88

Gene sequence:

>645_bases
ATGCGCAAGCTTGAAACGAAGACCATCGTCGTTGCCAGCCACAATGCCGGCAAAATCCGCGAGATCCAGGAATTGATCGG
GCCGCTCGGCTTCACCGCCAAGTCGGCCGCCGAGCTGAATTTCGTCGAACCCGATGAAACCGGCACGAGCTTCGAGGAGA
ATGCAACGATCAAGGCGGTCGCCTCGGCCAATGCAGCCGGCATGCCGGCGCTTTCAGACGATTCCGGGTTGGTGGTCGAC
GCGCTCGATGGCGATCCCGGCGTCTACACCGCCAATTGGGCGGAGACATCGAACGGCACGCGCGATTTCGACATGGCGAT
GGCGAAGGTGGAAAAGGCCTTGCAGGATGCGGGCGCAACGACGCCCGAACAGCGCACCGCACGTTTCGTCAGCGTGCTCT
GCCTCGCCTGGCCGGACGGACATACCGAACTCTTCCGCGGCGAAGTGGAGGGCAGCGTCGTCTGGCCGCCGCGCGGCGGC
CAAGGCTTCGGCTACGATCCGGTCTTCCAGCCGGAAGGCTACGGCGTCACCTTCGGCGAGATGAGCGGCGAGGAAAAACA
CGGCTGGAGCGTCGGCAAGCCGCAGGCGCTATCGCACCGGGCCCGCGCCTTCAAACTCTTTGTCGAAACCTGCCTGGAGG
CATAA

Upstream 100 bases:

>100_bases
TTGGCCGAACGGCGGCCGCTCGATCTATTTCCGCGATCCTGCCGGCAACAGCCTGGAATGCGCGGAGGCTAAAATCTGGG
GCATCGAACAGGATATCTGA

Downstream 100 bases:

>100_bases
GGTCACCACGTGGACAATTTCGACACGCCAGGCCGCCCCTCGCGCGATGCGGCGCTGCTGCCCGATACCGGCGAGCCCGG
CTTCGGCGTCTATGTGCATT

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRKLETKTIVVASHNAGKIREIQELIGPLGFTAKSAAELNFVEPDETGTSFEENATIKAVASANAAGMPALSDDSGLVVD
ALDGDPGVYTANWAETSNGTRDFDMAMAKVEKALQDAGATTPEQRTARFVSVLCLAWPDGHTELFRGEVEGSVVWPPRGG
QGFGYDPVFQPEGYGVTFGEMSGEEKHGWSVGKPQALSHRARAFKLFVETCLEA

Sequences:

>Translated_214_residues
MRKLETKTIVVASHNAGKIREIQELIGPLGFTAKSAAELNFVEPDETGTSFEENATIKAVASANAAGMPALSDDSGLVVD
ALDGDPGVYTANWAETSNGTRDFDMAMAKVEKALQDAGATTPEQRTARFVSVLCLAWPDGHTELFRGEVEGSVVWPPRGG
QGFGYDPVFQPEGYGVTFGEMSGEEKHGWSVGKPQALSHRARAFKLFVETCLEA
>Mature_214_residues
MRKLETKTIVVASHNAGKIREIQELIGPLGFTAKSAAELNFVEPDETGTSFEENATIKAVASANAAGMPALSDDSGLVVD
ALDGDPGVYTANWAETSNGTRDFDMAMAKVEKALQDAGATTPEQRTARFVSVLCLAWPDGHTELFRGEVEGSVVWPPRGG
QGFGYDPVFQPEGYGVTFGEMSGEEKHGWSVGKPQALSHRARAFKLFVETCLEA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=202, Percent_Identity=30.1980198019802, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1789324, Length=206, Percent_Identity=34.9514563106796, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322529, Length=216, Percent_Identity=28.2407407407407, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22897; Mature: 22897

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLETKTIVVASHNAGKIREIQELIGPLGFTAKSAAELNFVEPDETGTSFEENATIKAV
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEE
ASANAAGMPALSDDSGLVVDALDGDPGVYTANWAETSNGTRDFDMAMAKVEKALQDAGAT
ECCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TPEQRTARFVSVLCLAWPDGHTELFRGEVEGSVVWPPRGGQGFGYDPVFQPEGYGVTFGE
CCHHHHHHHHHHHEEECCCCCHHHEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEHHC
MSGEEKHGWSVGKPQALSHRARAFKLFVETCLEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKLETKTIVVASHNAGKIREIQELIGPLGFTAKSAAELNFVEPDETGTSFEENATIKAV
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEE
ASANAAGMPALSDDSGLVVDALDGDPGVYTANWAETSNGTRDFDMAMAKVEKALQDAGAT
ECCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TPEQRTARFVSVLCLAWPDGHTELFRGEVEGSVVWPPRGGQGFGYDPVFQPEGYGVTFGE
CCHHHHHHHHHHHEEECCCCCHHHEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEHHC
MSGEEKHGWSVGKPQALSHRARAFKLFVETCLEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]