BacMap

Definition	Escherichia coli O157:H7 str. EC4115, complete genome.
Accession	NC_011353
Length	5,572,075

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The map label for this gene is yahD [C]

Identifier: 209400992

GI number: 209400992

Start: 271435

End: 272151

Strand: Direct

Name: yahD [C]

Synonym: ECH74115_0253

Alternate gene names: 209400992

Gene position: 271435-272151 (Clockwise)

Preceding gene: 209400273

Following gene: 209399453

Centisome position: 4.87

GC content: 35.56

Gene sequence:

>717_bases
ATGAATTGCCTGATTTTTTTTAAGCCGAAAAATTACCACCTTAAGTCAAAATTAAATTATTATCCTATAACTCAGGCTGC
ATTTTTAGGTGAGACTGAGGTTGTAAGTAATTTAATTAAATTGGGTGTGGATCTGGATGCTCGTGGGGATTTGGGGCGTA
CCGCACTTAATGAGGCCGTAAGTAATGGGTATTTTGATATTGTTAAGCTTTTAGTAGAATCAGGAGCCGATCTTACTATA
AAGGATGAATTTGGGAAAACGGCATTAGAATTGGCTGAGGTACACCAGAATTATAAAATAGTTGAATGGCTATCACATTA
TAGAGATCATAATCCCATACCCGATTTTTCTGTACTTATTAATATCTACGGTGAGCGATATTTTGGTGGAGAGATTATAG
ATACAGATGCAAGGACAGAACTTGGCGAGGGGGTTCTTCATATAGCTGTTAGGAAAAGAAGACAATTAGATGTCAGATGT
TTTATTCAACATGGTGCCGATATAAATGCTAAGGCAAATAATGGCTTTGACTTCACTCCTTTGCATTATTCGATAGGGAT
AGGGGATTTTGATATGATGAAGCTTTTGTTGAAATTAGGTGCTGATATTTATTTGGAGAGTGAGATGGGATACTCCCCTA
TGGATTTGGCTATTTTGATGGGGGATAAGAGAATTATTTTTTATTTATATGGTTATATTTCTCATGTTTCTGAATAA

Upstream 100 bases:

>100_bases
TAATTATGCCCATTGATTGGTGAAAATGCTATAATATATTTTCTTATCTTTAATATGCTGCCGATTTATGGAGGAAGCCA
ATGGGGGGGAGGCTATAGTG

Downstream 100 bases:

>100_bases
GCCTGGGTGTAATGCAATCAAAAGATTGTAACGAATGAAATAATCTGTAAGTGAGGTGGCGTTAATTAGGACGATAATCG
CATGAAAAATCACCCCGTTA

Product: ankyrin repeat-containing domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNCLIFFKPKNYHLKSKLNYYPITQAAFLGETEVVSNLIKLGVDLDARGDLGRTALNEAVSNGYFDIVKLLVESGADLTI
KDEFGKTALELAEVHQNYKIVEWLSHYRDHNPIPDFSVLINIYGERYFGGEIIDTDARTELGEGVLHIAVRKRRQLDVRC
FIQHGADINAKANNGFDFTPLHYSIGIGDFDMMKLLLKLGADIYLESEMGYSPMDLAILMGDKRIIFYLYGYISHVSE

Sequences:

>Translated_238_residues
MNCLIFFKPKNYHLKSKLNYYPITQAAFLGETEVVSNLIKLGVDLDARGDLGRTALNEAVSNGYFDIVKLLVESGADLTI
KDEFGKTALELAEVHQNYKIVEWLSHYRDHNPIPDFSVLINIYGERYFGGEIIDTDARTELGEGVLHIAVRKRRQLDVRC
FIQHGADINAKANNGFDFTPLHYSIGIGDFDMMKLLLKLGADIYLESEMGYSPMDLAILMGDKRIIFYLYGYISHVSE
>Mature_238_residues
MNCLIFFKPKNYHLKSKLNYYPITQAAFLGETEVVSNLIKLGVDLDARGDLGRTALNEAVSNGYFDIVKLLVESGADLTI
KDEFGKTALELAEVHQNYKIVEWLSHYRDHNPIPDFSVLINIYGERYFGGEIIDTDARTELGEGVLHIAVRKRRQLDVRC
FIQHGADINAKANNGFDFTPLHYSIGIGDFDMMKLLLKLGADIYLESEMGYSPMDLAILMGDKRIIFYLYGYISHVSE

Specific function: Unknown

COG id: COG0666

COG function: function code R; FOG: Ankyrin repeat

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 18 ANK repeats [H]

Homologues:

Organism=Homo sapiens, GI87239981, Length=210, Percent_Identity=30, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI13376842, Length=217, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI268607595, Length=228, Percent_Identity=31.140350877193, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI62988328, Length=228, Percent_Identity=31.140350877193, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI24233530, Length=198, Percent_Identity=30.8080808080808, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI30425444, Length=214, Percent_Identity=29.4392523364486, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI52426737, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI188595682, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI68131557, Length=230, Percent_Identity=27.8260869565217, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI52426735, Length=218, Percent_Identity=27.5229357798165, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32967601, Length=239, Percent_Identity=26.7782426778243, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI70780357, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI70780359, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI70780355, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI70780353, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI215598574, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI55742857, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI116875852, Length=196, Percent_Identity=27.0408163265306, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI55741641, Length=211, Percent_Identity=29.3838862559242, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI38327522, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI89363047, Length=217, Percent_Identity=24.4239631336406, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI304361760, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI304361757, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19718741, Length=185, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71981414, Length=225, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145251, Length=225, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17542700, Length=225, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71981389, Length=225, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71981411, Length=225, Percent_Identity=25.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320470, Length=179, Percent_Identity=30.1675977653631, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161082092, Length=229, Percent_Identity=27.9475982532751, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI161082089, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161082085, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161082106, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161082096, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161082081, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161082110, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161082099, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281359521, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281359519, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28558752, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28558750, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28558756, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28558754, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24650843, Length=211, Percent_Identity=29.8578199052133, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356741, Length=206, Percent_Identity=27.1844660194175, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002110
- InterPro:   IPR020683
- InterPro:   IPR007685 [H]

Pfam domain/function: PF00023 Ank; PF04607 RelA_SpoT [H]

EC number: NA

Molecular weight: Translated: 26982; Mature: 26982

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCLIFFKPKNYHLKSKLNYYPITQAAFLGETEVVSNLIKLGVDLDARGDLGRTALNEAV
CCEEEEECCCCCEECCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SNGYFDIVKLLVESGADLTIKDEFGKTALELAEVHQNYKIVEWLSHYRDHNPIPDFSVLI
HCCHHHHHHHHHHCCCCEEEEHHHCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHH
NIYGERYFGGEIIDTDARTELGEGVLHIAVRKRRQLDVRCFIQHGADINAKANNGFDFTP
HHHCCEECCCEEECCCCHHHHHCCHHEEHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
LHYSIGIGDFDMMKLLLKLGADIYLESEMGYSPMDLAILMGDKRIIFYLYGYISHVSE
EEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCEEEHHHHHHHHHHCC
>Mature Secondary Structure
MNCLIFFKPKNYHLKSKLNYYPITQAAFLGETEVVSNLIKLGVDLDARGDLGRTALNEAV
CCEEEEECCCCCEECCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SNGYFDIVKLLVESGADLTIKDEFGKTALELAEVHQNYKIVEWLSHYRDHNPIPDFSVLI
HCCHHHHHHHHHHCCCCEEEEHHHCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHH
NIYGERYFGGEIIDTDARTELGEGVLHIAVRKRRQLDVRCFIQHGADINAKANNGFDFTP
HHHCCEECCCEEECCCCHHHHHCCHHEEHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
LHYSIGIGDFDMMKLLLKLGADIYLESEMGYSPMDLAILMGDKRIIFYLYGYISHVSE
EEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA