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The map label for this gene is yiaV [H]

Identifier: 209400974

GI number: 209400974

Start: 4597401

End: 4598537

Strand: Reverse

Name: yiaV [H]

Synonym: ECH74115_4954

Alternate gene names: 209400974

Gene position: 4598537-4597401 (Counterclockwise)

Preceding gene: 209399421

Following gene: 209396238

Centisome position: 82.53

GC content: 50.66

Gene sequence:

>1137_bases
ATGGATTTACTGATTATTTTGACCTATGTGGCTTTTGCATGGGCAATGTTTAAGATCTTCAAAATTCCCGTAAATAAATG
GACCATTCCCACAGCGGCCCTGGGTGGAATATTTATTGTCAGCGGTCTAATTCTGTTAATGAACTATAACCATCCGTATA
CCTTTAAAGCGCAAAAAGCGGTTATTTCTATTCCTGTTGTCCCACAGGTGACAGGCGTGGTGATAGAAGTGACGGATAAG
AAAAATACGCTGATTAAAAAAGGTGAGGTGCTATTTCGACTGGACCCGACGCGTTATCAGGCGCGGGTGGATCGGCTGAT
GGCGGATATCGTTACCGCAGAACATAAACAGCGGGCGTTGGGCGCAGAGTTAGATGAGATGGCGGCGAATACTCAGAAGG
CAAAGGCCACGCGGGATAAATTCGCTAAGGAGTACCAGCGTTACGCACGCGGCAGCCAGGCGAAAGTAAACCCGTTTTCA
GAACGCGATATTGATGTGGCACGGCAAAATTATCTGGCGCAGGAAGCCTCCGTAAAGTCATCGGCGGCGGAACAAAAACA
GATCCAGAGCCAGCTGGATAGCCTGGTGTTGGGTGAACATTCTCAAATCGCCAGCCTGAAAGCGCAGCTCGCGGAAGCAA
AATATAACCTTGAGCAGACGATAGTGCGTGCGCCGAGCGATGGTTATGTGACCCAAGTGCTGATTCGTCCGGGTACCTAT
GCCGCGTCGCTGCCGCTACGTCCGGTGATGGTGTTTATACCCGATCAGAAACGACAAATCGTGGCGCAGTTCCGTCAGAA
CTCCTTGCTGCGCCTGGCTCCCGGCGATGATGCGGAAGTGGTATTTAACGCTCTGCCAGGCAAAGTGTTCAGCGGTAAGC
TGGCAGCCATTAGTCCAGCTGTTCCCGGCGGAGCTTATCAGTCGACCGGCACCTTACAGACGTTAAACACAGCGCCGGGT
TCAGATGGCGTTATCGCGACCATTGAACTGAATGAGCACACTGATTTGAGCGCTTTACCAGACGGTATTTACGCTCAGGT
GGCGGTCTACTCTGATCATTTCAGCCATGTCTCGGTGATGCGCAAAGTGTTATTACGCATGACCAGCTGGGTGCATTACC
TTTATCTCGATCATTAA

Upstream 100 bases:

>100_bases
TGCAAAGCCATGATTCATCCGTTATGCAACTGCAACAGCGCATTGCCGGGCTGGAGAAACAGCTCGCCGACATCAAATCC
TCTTCTGCCGAGTAATACTT

Downstream 100 bases:

>100_bases
TCTTCGCTTTCCGCCGCTTGTTCAGGCCGCAGTTGCTGCGACTGAGCAAGCTGGTGGCGAATTTCACGCAGCATTTCATC
CAGCACATACTGGACCCGCC

Product: auxiliary transport protein, membrane fusion protein (MFP) family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLILLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDK
KNTLIKKGEVLFRLDPTRYQARVDRLMADIVTAEHKQRALGAELDEMAANTQKAKATRDKFAKEYQRYARGSQAKVNPFS
ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLEQTIVRAPSDGYVTQVLIRPGTY
AASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGDDAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPG
SDGVIATIELNEHTDLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH

Sequences:

>Translated_378_residues
MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLILLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDK
KNTLIKKGEVLFRLDPTRYQARVDRLMADIVTAEHKQRALGAELDEMAANTQKAKATRDKFAKEYQRYARGSQAKVNPFS
ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLEQTIVRAPSDGYVTQVLIRPGTY
AASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGDDAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPG
SDGVIATIELNEHTDLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH
>Mature_378_residues
MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLILLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDK
KNTLIKKGEVLFRLDPTRYQARVDRLMADIVTAEHKQRALGAELDEMAANTQKAKATRDKFAKEYQRYARGSQAKVNPFS
ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLEQTIVRAPSDGYVTQVLIRPGTY
AASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGDDAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPG
SDGVIATIELNEHTDLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=378, Percent_Identity=99.4708994708995, Blast_Score=771, Evalue=0.0,
Organism=Escherichia coli, GI1790024, Length=378, Percent_Identity=76.7195767195767, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI1790519, Length=258, Percent_Identity=29.8449612403101, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87081951, Length=269, Percent_Identity=23.7918215613383, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41771; Mature: 41771

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLILLMNYNHPYTFKAQKA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCEEEEECCE
VISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQARVDRLMADIVTAEHKQRAL
EEEECCCCCCCEEEEEEECCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
GAELDEMAANTQKAKATRDKFAKEYQRYARGSQAKVNPFSERDIDVARQNYLAQEASVKS
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLEQTIVRAPSDGYVTQVLIRPGTY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHEECCCCCCEEEEEECCCCE
AASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGDDAEVVFNALPGKVFSGKLAAISPA
EECCCCCEEEEEECCHHHHHHHHHHHCCEEEECCCCCHHHHEECCCCCHHCCCEEEECCC
VPGGAYQSTGTLQTLNTAPGSDGVIATIELNEHTDLSALPDGIYAQVAVYSDHFSHVSVM
CCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
RKVLLRMTSWVHYLYLDH
HHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLILLMNYNHPYTFKAQKA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCEEEEECCE
VISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQARVDRLMADIVTAEHKQRAL
EEEECCCCCCCEEEEEEECCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
GAELDEMAANTQKAKATRDKFAKEYQRYARGSQAKVNPFSERDIDVARQNYLAQEASVKS
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLEQTIVRAPSDGYVTQVLIRPGTY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHEECCCCCCEEEEEECCCCE
AASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGDDAEVVFNALPGKVFSGKLAAISPA
EECCCCCEEEEEECCHHHHHHHHHHHCCEEEECCCCCHHHHEECCCCCHHCCCEEEECCC
VPGGAYQSTGTLQTLNTAPGSDGVIATIELNEHTDLSALPDGIYAQVAVYSDHFSHVSVM
CCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
RKVLLRMTSWVHYLYLDH
HHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]