Click here to switch to the map view.

The map label for this gene is mltE [H]

Identifier: 209400733

GI number: 209400733

Start: 1621375

End: 1621986

Strand: Direct

Name: mltE [H]

Synonym: ECH74115_1680

Alternate gene names: 209400733

Gene position: 1621375-1621986 (Clockwise)

Preceding gene: 209396444

Following gene: 209399605

Centisome position: 29.1

GC content: 51.8

Gene sequence:

>612_bases
GTGAAATTGAGATGGTTTGCCTTTTTGATTGTGTTATTAGCGGGTTGTTCATCAAAGCATGACTATACGAACCCGCCGTG
GAACGCGAAAGTTCCGGTGCAACGTGCGATGCAGTGGATGCCAATAAGCCAGAAAGCCGGTGCAGCCTGGGGCGTCGATC
CACAATTGATCACGGCGATTATCGCTATCGAATCGGGTGGTAATCCGAACGCGGTGAGTAAATCGAATGCCATTGGTTTG
ATGCAGTTAAAAGCTTCAACCTCCGGACGTGATGTTTATCGGCGTATGGGCTGGAGTGGTGAGCCGACGACCAGCGAGCT
GAAAAATCCGGAGCGTAATATTTCTATGGGGGCGGCTTACCTGAATATTCTGGAAACCGGCCCGCTGGCAGGCATTGAAG
ATCCGAAGGTACTGCAATATGCGCTGGTGGTGTCATATGCTAACGGGGCAGGTGCGCTGCTACGGACTTTCTCGTCAGAT
CGGAAAAAGGCAATCAGCAAAATCAACGATCTGGATGCTGACGAGTTCCTCGATCACGTAGCGCGAAATCATCCTGCGCC
GCAGGCTCCGCGCTATATCTACAAACTTGAGCAGGCACTGGACGCGATGTAA

Upstream 100 bases:

>100_bases
TGGCAATTCCTTGCTGACAACAGATACGAAATGTATATCATGCCGCTTAGGTGTGCCGTTGTCACCTCAACGGCGATTCC
AGGCTATAAGGATAGAAGAA

Downstream 100 bases:

>100_bases
ATCAGTCGCGTACTTTGTCCGCTTTCTCCCGGGCTTCCCGCTCGAGAGAGAAAATAATCCGCTGTAATTGCCGCTCCACC
GTCGGGCTGACGTTAAGAAA

Product: membrane-bound lytic murein transglycosylase E

Products: NA

Alternate protein names: Peptidoglycan lytic endotransglycosylase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM

Sequences:

>Translated_203_residues
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
>Mature_203_residues
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (Potential) [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87081855, Length=203, Percent_Identity=99.5073891625616, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI87082191, Length=166, Percent_Identity=40.3614457831325, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 22213; Mature: 22213

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAI
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHHHHH
IAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAY
HEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHH
LNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHV
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ARNHPAPQAPRYIYKLEQALDAM
HHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAI
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHHHHH
IAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAY
HEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHH
LNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHV
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ARNHPAPQAPRYIYKLEQALDAM
HHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12384590 [H]