Click here to switch to the map view.

The map label for this gene is pgpA [H]

Identifier: 209400639

GI number: 209400639

Start: 504439

End: 504945

Strand: Direct

Name: pgpA [H]

Synonym: ECH74115_0500

Alternate gene names: 209400639

Gene position: 504439-504945 (Clockwise)

Preceding gene: 209398517

Following gene: 209397021

Centisome position: 9.05

GC content: 53.25

Gene sequence:

>507_bases
TTGCCACGCCATAAAGATGTCGCGAAAAGTCGCCTGAAGATGAGTAATCCGTGGCATCTGCTTGCTGTCGGATTCGGAAG
TGGATTAAGCCCAATCGTTCCTGGCACGATGGGATCGCTGGCGGCGATTCCGTTCTGGTATCTGATGACCTTTTTGCCCT
GGCAGCTCTACTCGCTGGTGGTGATGTTGGGGATCTGTATCGGCGTCTATCTTTGTCATCAAACGGCGAAAGACATGGGG
GTGCACGATCACGGTAGCATCGTATGGGATGAGTTTATTGGCATGTGGATCACCCTGATGGCGCTGCCGACCAATGACTG
GCAGTGGGTCGCCGCCGGGTTTGTGATTTTCCGTATTCTGGATATGTGGAAGCCGTGGCCGATCCGCTGGTTTGATCGCA
ATGTACATGGCGGCATGGGGATCATGATCGATGATATTGTCGCCGGGGTGATTTCCGCAGGCATCCTGTACTTTATCGGT
CATCACTGGCCGCTGGGTATTCTTTAA

Upstream 100 bases:

>100_bases
CCGTTTACCTGTATCGGGCAAATGACCGCCGATATCGAAGGGCTTTGTTTTATTCGTGACGGCGAACCTGTCACGTTAGA
CTGGAAAGGATATGACCATT

Downstream 100 bases:

>100_bases
ATGCCATTGACCGGGAGGTGTAGGCGATTCCAGACCACCCGGTTTGATTTATAAATGAACAGTGCCCCAATTTTGGGGCA
CTCTGTTAAAGTAAAACCCG

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMG
VHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIG
HHWPLGIL

Sequences:

>Translated_168_residues
MPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMG
VHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIG
HHWPLGIL
>Mature_167_residues
PRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGV
HDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIGH
HWPLGIL

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=168, Percent_Identity=99.4047619047619, Blast_Score=337, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 19004; Mature: 18873

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLV
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIGHHWPLGIL
HHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLV
CCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIGHHWPLGIL
HHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]