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The map label for this gene is allR [H]

Identifier: 209400082

GI number: 209400082

Start: 628916

End: 629686

Strand: Direct

Name: allR [H]

Synonym: ECH74115_0607

Alternate gene names: 209400082

Gene position: 628916-629686 (Clockwise)

Preceding gene: 209396687

Following gene: 209400464

Centisome position: 11.29

GC content: 52.27

Gene sequence:

>771_bases
GTGGCACAGAAGGGCGCACAGGCATTAGAGCGGGGAATTGCGATTCTGCAATATCTGGAAAAAAGTGGGGGAAGTTCGTC
GGTTAGCGATATTTCTCTCAATCTGGATTTGCCGCTCTCCACGACCTTTCGCTTGCTGAAGGTTTTACAGGCAGCGGATT
TTGTCTATCAGGACAGTCAGTTAGGCTGGTGGCATATAGGATTAGGTGTCTTTAACGTCGGTGCGGCGTACATCCATAAC
CGCGATGTCCTCTCCGTCGCCGGGCCGTTTATGCGCCGCCTGATGTTACTTTCCGGCGAAACGGTCAATGTCGCGATCCG
TAACGGCAATGAAGCGGTATTAATTGGTCAGTTAGAGTGTAAATCGATGGTCAGGATGTGCGCGCCACTGGGCAGTCGTC
TGCCACTGCATGCTTCCGGTGCGGGCAAAGCGCTGCTTTATCCGCTGGCGGAAGAGGAGTTGATGAGCATCATTCTGCAA
ACCGGTTTGCAGCAGTTTACGCCAACTACGCTTGTGGATATGCCCACCCTGCTGAAGGACCTGGAACAAGCGCGTGAACT
GGGCTATACCGTAGATAAAGAAGAGCATGTTGTAGGTCTGAATTGCATAGCTTCAGCAATTTACGATGATGTAGGTAGCG
TTGTTGCCGCTATCTCCATCTCCGGGCCTTCATCAAGACTGACAGAAGATCGTTTTGTCAGTCAGGGTGAGCTGGTCAGA
GACACCGCCCGCGATATCAGCACGGCGTTGGGACTGAAAGCACATCCATAG

Upstream 100 bases:

>100_bases
GATAAACTAATTGTTCATTGTTTATGCTCACTTGTAGGTCGGAGTTAACGTAGGTATGACGGAAGTTAGACGGCGCGGCA
GGCCAGGACAGGCGGAGCCT

Downstream 100 bases:

>100_bases
TGTCTGTCGCATCCCGCTCTGCGGAGCGGGTTTTTTTGACAAAATTTGAAAGTTGGAAAATTTTTCCAATTAATAGAGGT
AGGAATAAAATGGCAAAAAT

Product: DNA-binding transcriptional repressor AllR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHN
RDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQ
TGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVR
DTARDISTALGLKAHP

Sequences:

>Translated_256_residues
MAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHN
RDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQ
TGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVR
DTARDISTALGLKAHP
>Mature_255_residues
AQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNR
DVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQT
GLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRD
TARDISTALGLKAHP

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=256, Percent_Identity=99.609375, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=42.914979757085, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=30.6451612903226, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1788131, Length=229, Percent_Identity=30.1310043668122, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789999, Length=260, Percent_Identity=30, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790752, Length=254, Percent_Identity=26.7716535433071, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788581, Length=248, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27580; Mature: 27449

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEECCC
LGWWHIGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLEC
CCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECHHH
KSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKD
HHHHHHHHCCCCCCCEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVR
HHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEECCCCCHHCCHHHHHCCCHHHH
DTARDISTALGLKAHP
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEECCC
LGWWHIGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLEC
CCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECHHH
KSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKD
HHHHHHHHCCCCCCCEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVR
HHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEECCCCCHHCCHHHHHCCCHHHH
DTARDISTALGLKAHP
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA