Click here to switch to the map view.

The map label for this gene is aslB [H]

Identifier: 209399680

GI number: 209399680

Start: 4879686

End: 4880921

Strand: Direct

Name: aslB [H]

Synonym: ECH74115_5236

Alternate gene names: 209399680

Gene position: 4879686-4880921 (Clockwise)

Preceding gene: 209398945

Following gene: 209396473

Centisome position: 87.57

GC content: 51.54

Gene sequence:

>1236_bases
ATGCTGCAACAGGTTCCAACGCGTGCTTTTCATGTGATGGCGAAACCGAGCGGTTCCGATTGTAATCTGAACTGTGACTA
CTGTTTTTATCTCGAAAAACAATCCCTTTACCGCGAAAAGCCAGTCACGCATATGGACGATGACACGCTGGAAGCGTATG
TCCGTCACTATATCGCTGCCAGCGAACCGCAAAACGAAGTGGCTTTTACCTGGCAGGGCGGCGAACCAACGCTACTCGGG
CTGGAGTTTTACCGCCGTGCCGTGGCGCTACAGGCGAAATATGGTGCTGGCAGGAAGATAAGTAACAGCTTCCAGACTAA
CGGCGTACTGCTCGATGATGAATGGTGTGCATTTCTGGCAGAAAATCATTTTCTTGTTGGGTTATCGCTGGATGGTCCGG
CTGAGATCCACAATCAATATCGCGTGACAAAAGGCGGCAGACCCACGCATAAACTGGTGATGCGTGCCCTGACGCTCCTG
CAAAAACATCATGTCGACTATAACGTGCTGGTCTGCGTCAACCGCACCAGCGCGCAGCAACCGTTACAGGTTTATGATTT
TTTGTGCGATGCGGGAGTCGAATTCATCCAGTTTATTCCGGTGGTCGAGCGCCTGGCTGATGAAACGACTGCCCGCGAAG
GACTGAAACTACATGCGCCTGGTGATATTCAGGGGGAACTGACGGAATGGTCTGTGCGCCCCGATGAATTTGGTGAATTT
CTGGTGGCGATATTCGACCACTGGATTAAACGCGACGTCGGCAAGATTTTCGTGATGAATATCGAATGGGCGTTTGCCAA
TTTTGTCGGTGCGCCGGGTGCGGTTTGCCATCATCAGCCAACCTGTGGGCGCTCGGTGATTGTTGAGCACAATGGCGACG
TTTACGCCTGCGATCACTATGTTTATCCGCAATATCGACTGGGGAATATGCACCAGCAAACAATTGCAGAAATGATCGAT
TCCCCGCAACAGCAGGTGTTTGGTGAAGATAAATTTAAGCAATTACCGGCGCAGTGTCGCAGTTGTAACGTGTTAAAAGC
ATGTTGGGGAGGCTGCCCGAAACACCGCTTCATGCTCGATGCCAGCGGCAAACCGGGACTGAATTATTTGTGTGCCGGGT
ATCAGCGTTATTTCCGCCATCTACCGCCATATCTTAAAGCAATGGCTGATTTGCTGGCGCACGGTCGCCCGGCCAGCGAC
ATTATGCAGGCGCATTTGCTGGTGGTGAGTAAGTAA

Upstream 100 bases:

>100_bases
GTCACCCTCCCTTCGCAATAAACGCCCGTAATAACTCATTGCCCCACGGTATGATTTCGCCCTTAACGTATTGAAGGATG
ACTTCAGGCAAGGAGCGACC

Downstream 100 bases:

>100_bases
AAAAGCGGCCATTTTGTGGTCGCCTGCGGTTGATTGCCGGATGCGGCGTAAACGCCTTATCCGGCCTACATGATCGTGCA
AATTCAATAAATTGCAGCGT

Product: arylsulfatase-activating protein AslB

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETTAREGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVSK

Sequences:

>Translated_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETTAREGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVSK
>Mature_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETTAREGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVSK

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=411, Percent_Identity=98.2968369829684, Blast_Score=851, Evalue=0.0,
Organism=Escherichia coli, GI87081923, Length=392, Percent_Identity=40.8163265306122, Blast_Score=330, Evalue=9e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 46542; Mature: 46542

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHC
SEPQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
CCCCCCEEEEEECCCCEEEHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECCHHHHHHH
ENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSAQQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETTAREGLKLHAPGDIQGELTEWSVRPDEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEECE
VYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMQAHLLVVSK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC
>Mature Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHC
SEPQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
CCCCCCEEEEEECCCCEEEHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEECCHHHHHHH
ENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSAQQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETTAREGLKLHAPGDIQGELTEWSVRPDEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEECE
VYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMQAHLLVVSK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]