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The map label for this gene is flgM [H]

Identifier: 209399485

GI number: 209399485

Start: 1432565

End: 1432858

Strand: Reverse

Name: flgM [H]

Synonym: ECH74115_1450

Alternate gene names: 209399485

Gene position: 1432858-1432565 (Counterclockwise)

Preceding gene: 209398728

Following gene: 209397144

Centisome position: 25.71

GC content: 51.7

Gene sequence:

>294_bases
ATGAGTATTGATCGCACTTCGCCTCTGAAGCCCGTAAGCACCGTTCAACCGCGCGAAACCACTGACGCGCCGGTAACGAA
CACCCGAGCGGCAAAAACAACAGCCTCCACCAGCACCAGTGTGACGTTAAGCGACGCGCAAGCAAAACTGATGCAACCCG
GCAGCAGTGATATCAATCTTGAACGTGTCGAAGCGTTAAAACTGGCGATTCGTAACGGTGAACTAAAAATGGACACCGGC
AAAATTGCCGATGCGCTGATCAACGAAGCGCAGCAAGACTTGCAGAGTAATTAA

Upstream 100 bases:

>100_bases
TGGGAATATTCTTATAAACCTGTAAGCTGTTAAAGATTACCCGTCCCTTGCCGATAAATAAGCAACACATGATAAAAGCG
CCCTCAATGAGGAATAAACC

Downstream 100 bases:

>100_bases
TCGTATGACGCGTCTTGCAGAGATCCTCGACCAGATGTCCGCTGTGCTTAACGATCTCAAAACGGTAATGGATCAAGAGC
AGCAACATCTCTCTATGGGG

Product: anti-sigma28 factor FlgM

Products: NA

Alternate protein names: Anti-sigma-28 factor [H]

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTG
KIADALINEAQQDLQSN

Sequences:

>Translated_97_residues
MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTG
KIADALINEAQQDLQSN
>Mature_96_residues
SIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGK
IADALINEAQQDLQSN

Specific function: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of

COG id: COG2747

COG function: function code KNU; Negative regulator of flagellin synthesis (anti-sigma28 factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flgM family [H]

Homologues:

Organism=Escherichia coli, GI1787311, Length=97, Percent_Identity=98.9690721649485, Blast_Score=191, Evalue=9e-51,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007412 [H]

Pfam domain/function: PF04316 FlgM [H]

EC number: NA

Molecular weight: Translated: 10355; Mature: 10224

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCH
ERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN
HHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCH
ERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN
HHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9095196 [H]