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The map label for this gene is yjiR [H]

Identifier: 209397786

GI number: 209397786

Start: 5506926

End: 5508338

Strand: Reverse

Name: yjiR [H]

Synonym: ECH74115_5854

Alternate gene names: 209397786

Gene position: 5508338-5506926 (Counterclockwise)

Preceding gene: 209396668

Following gene: 209399400

Centisome position: 98.86

GC content: 55.27

Gene sequence:

>1413_bases
ATGACGCGTTATCAACATCTGGCGACTCTACTTGCCGAGCGGATTGAGCAAGGGCTGTATCGTCACGGGGAGAAATTGCC
GTCGGTGCGCAGCTTAAGTCAGGAGCACGGCGTCAGCATCAGCACCGTGCAGCAGGCGTACCAGACGCTGGAGACGATGA
AGCTCATCACTCCGCAGCCGCGTTCGGGTTATTTTGTCGCACAACGTAAAGCCCAGCCGCCAGTGCCGCCGATGACGCGT
CCGGTGCAGCGCCCAGTGGAAATTACCCAGTGGGATCTGGTGCTGGATATGCTGGTGGCGCATAGCGACAGTTCCATTGT
TCCGTTAAGCAAAAGCACGCCGGATGTCGAAACGCCCAGCCTGAAACCGCTGTGGCGGGAGCTAAGCCGGGTGGTGCAGC
ATAATCTGCAAACCGTTCTCGGTTATGACTTGCTAGCCGGTCAGCGGGTATTGCGCGAGCAGGTTGCCCGCCTGATGCTC
GACAGCGGCTCGGTGGTCACTGCCGATGACATCATCATCACCAGCGGCTGCCATAACTCGATGTCGCTAGCGTTAATGGC
GGTGTGTAAACCGGGCGATATTGTCGCGGTCGAATCCCCCTGTTATTACGGTTCAATGCAGATGCTGCGCGGCATGGGCG
TGAAAGTGATTGAAATCCCAACCGATCCAGAAACAGGCATCAGCGTTGAAGCGCTGGAACTGGCGCTGGAACAGTGGCCG
ATTAAAGGCATCATTCTGGTGCCAAACTGTAATAATCCGCTGGGATTTATTATGCCGGACGCGCGCAAACGGGCCGTTCT
CTCTCTCGCTCAGCGTCATGATATTGTGATTTTTGAAGATGATGTCTACGGCGAACTGGCAACGGAGTATCCGCGCCCGC
GGACCATTCATTCCTGGGATATCGACGGGCGAGTGCTGTTGTGCAGCTCGTTCAGTAAAAGTATTGCTCCAGGCCTGCGC
GTGGGTTGGGTCGCACCGGGGCGTTATCACGATAAACTGATGCATATGAAATACGCCATCAGCAGCTTTAATGTGCCGTC
CACGCAAATGGCGGCGGCAACGTTTGTGCTGGAAGGTCACTATCATCGCCATATCCGGCGGATGCGGCAGATCTATCAGC
GCAATTTGGCGCTTTATACCTGCTGGATACGGGAATATTTTCCCTGCGAAATCTGTATTACGCGCCCGAAAGGCGGATTT
TTACTGTGGATAGAATTGCCTGAACAGGTCGATATGGTCTGCGTCACGCGGCAGCTGTGCCGCATGAAAATCCAGGTGGC
GGCAGGCTCGATTTTCTCAGCTTCCGGCAAATACCGTAACTGCCTGCGCATCAACTGTGCTTTGCCACTCAGCGAAACTT
ATCGCGAAGCGCTGAAGCAAATTGGCGAGGCCGTGTATCGGGCAATGGAATAA

Upstream 100 bases:

>100_bases
TGTTTAACATACAGACAGGTTAAAACAGCATCTGCATCCGGTTTTTTAGCCTCATCTGTACCGGTTTTTCTTTCTGTATG
GTCCAAATAAGGAATACAGC

Downstream 100 bases:

>100_bases
ATTAGAATTAGTGGCGAAGCACCTGATTTATTCTCACGAATCGCCTGTGACTCGTTTTATCTTTGCAGGATCATAGCCAC
GTTCCGGCATGGCTTAGGTA

Product: transcriptional regulator, GntR family/aminotransferase, classes I and II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTR
PVQRPVEITQWDLVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQVARLML
DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIEIPTDPETGISVEALELALEQWP
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLR
VGWVAPGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEICITRPKGGF
LLWIELPEQVDMVCVTRQLCRMKIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME

Sequences:

>Translated_470_residues
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTR
PVQRPVEITQWDLVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQVARLML
DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIEIPTDPETGISVEALELALEQWP
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLR
VGWVAPGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEICITRPKGGF
LLWIELPEQVDMVCVTRQLCRMKIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
>Mature_469_residues
TRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTRP
VQRPVEITQWDLVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQVARLMLD
SGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIEIPTDPETGISVEALELALEQWPI
KGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLRV
GWVAPGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEICITRPKGGFL
LWIELPEQVDMVCVTRQLCRMKIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=284, Percent_Identity=28.5211267605634, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI33469970, Length=284, Percent_Identity=28.5211267605634, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI4507369, Length=187, Percent_Identity=25.1336898395722, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790797, Length=470, Percent_Identity=98.936170212766, Blast_Score=964, Evalue=0.0,
Organism=Escherichia coli, GI1787710, Length=466, Percent_Identity=34.7639484978541, Blast_Score=298, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17567663, Length=344, Percent_Identity=23.546511627907, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=184, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321929, Length=428, Percent_Identity=24.7663551401869, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321000, Length=356, Percent_Identity=24.1573033707865, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356535, Length=336, Percent_Identity=23.8095238095238, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859735, Length=261, Percent_Identity=21.8390804597701, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53049; Mature: 52917

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQP
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
RSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDLVLDMLVAHSDSSIVPLSKSTPDVETPS
CCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
LKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQVARLMLDSGSVVTADDIIITSGCHNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCC
MSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIEIPTDPETGISVEALELALEQWP
HHEEEEEEECCCCEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWD
CCEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHCCCCCCCEEEEC
IDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGH
CCCCEEEEECCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHEECCH
YHRHIRRMRQIYQRNLALYTCWIREYFPCEICITRPKGGFLLWIELPEQVDMVCVTRQLC
HHHHHHHHHHHHHCCCCEEEEEHHHCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
RMKIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
HHHHHEECCCEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQP
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
RSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDLVLDMLVAHSDSSIVPLSKSTPDVETPS
CCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
LKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQVARLMLDSGSVVTADDIIITSGCHNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCC
MSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIEIPTDPETGISVEALELALEQWP
HHEEEEEEECCCCEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWD
CCEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHCCCCCCCEEEEC
IDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGH
CCCCEEEEECCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHEECCH
YHRHIRRMRQIYQRNLALYTCWIREYFPCEICITRPKGGFLLWIELPEQVDMVCVTRQLC
HHHHHHHHHHHHHCCCCEEEEEHHHCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
RMKIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
HHHHHEECCCEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]