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The map label for this gene is yihV [H]

Identifier: 209397229

GI number: 209397229

Start: 4973422

End: 4974318

Strand: Direct

Name: yihV [H]

Synonym: ECH74115_5330

Alternate gene names: 209397229

Gene position: 4973422-4974318 (Clockwise)

Preceding gene: 209396239

Following gene: 209398202

Centisome position: 89.26

GC content: 56.08

Gene sequence:

>897_bases
ATGATTCGTGTTGCTTGTGTAGGTATAACCGTGATGGATCGCATCTATTACGTGGAAGGGTTACCGACGGAGAGCGGTAA
ATACGTGGCGAGAAATTATACGGAAGTTGGTGGCGGGCCAGCGGCGACGGCAGCGGTTGCGGCGGCAAGACTGGGAGCGC
AGGTTGATTTTATTGGGCGCGTCGGTGATGACGACACCGGCAACAGCCTGCTGGCAGAGCTGGAATCCTGGGGCGTTAAC
ACCCGCTACACCAAACGGTATAAACAGGCGAAATCGTCGCAATCCGCCATCATGGTGGATGCCAAAGGCGAGCGGATAAT
CATTAACTACCCCAGCCCGGACCTGCTGCCTGACGCAGAGTGGTTGGAGGAAATTGATTTCTCTCAGTGGGATGTTGTGC
TGGCAGATGTACGCTGGCACGACGGCGCTAAAAAAGCCTTCACTCTGGCCCGGCAGGCGGGCGTGATGACCGTTCTGGAC
GGTGATATTACGCCGCAGGATATCAGCGAGCTGGTGGCATTAAGCGATCATGCGGCCTTTTCAGAACCGGGTCTGGCGCG
CTTAACGGGCGTGAAAGAGATGGCCAGTGCGCTAAAACAGGCACAAACGCTCACAAATGGTCATGTCTATGTGACCCAGG
GCAGCGCAGGCTGTGACTGGCTGGAAAATGGCGGGCGTCAACATCAACCGGCCTTCAAAGTTGATGTGGTAGATACCACA
GGTGCGGGTGATGTTTTTCACGGCGCATTGGCGGTGGTGCTGGCAACAGGTGGGGATTTAGCGGAGTCAGTCCGCTTCGC
CAGCGGTGTAGCGGCGTCGAAATGCACGCGTCCCGGTGGACGAGCCGGGATCCCTGACTGTGATCAAACCCGATCTTTTT
TGTCACTTTTTGTATAA

Upstream 100 bases:

>100_bases
ATCGTATTTGTAATTTATAGTCAAAAAATTGACAGACGTCACTTTTTAAACAATTGGTGAAATTAAAATGAACGCATCCC
AAAATGTTTAAGGAATGACC

Downstream 100 bases:

>100_bases
AATGCCAGGGTGATGGTTTTTCGAGGAATTTTCATGAGCCTTACCGAACTAACCGGTAACCCGCGGCACGACCAACTCCT
CATGCTGATCGCCGAGCGTG

Product: kinase, PfkB family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVN
TRYTKRYKQAKSSQSAIMVDAKGERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTT
GAGDVFHGALAVVLATGGDLAESVRFASGVAASKCTRPGGRAGIPDCDQTRSFLSLFV

Sequences:

>Translated_298_residues
MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVN
TRYTKRYKQAKSSQSAIMVDAKGERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTT
GAGDVFHGALAVVLATGGDLAESVRFASGVAASKCTRPGGRAGIPDCDQTRSFLSLFV
>Mature_298_residues
MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVN
TRYTKRYKQAKSSQSAIMVDAKGERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTT
GAGDVFHGALAVVLATGGDLAESVRFASGVAASKCTRPGGRAGIPDCDQTRSFLSLFV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=270, Percent_Identity=31.4814814814815, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4557693, Length=297, Percent_Identity=25.5892255892256, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI87082343, Length=298, Percent_Identity=98.3221476510067, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1790193, Length=291, Percent_Identity=30.2405498281787, Blast_Score=84, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=30.3630363036304, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=25.7328990228013, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356677, Length=286, Percent_Identity=27.972027972028, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24662680, Length=298, Percent_Identity=23.8255033557047, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 31684; Mature: 31684

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGR
CEEEEEEHHHHHHHHHEEECCCCCCCCEEECCCHHCCCCHHHHHHHHHHHHCCCEEEEEC
VGDDDTGNSLLAELESWGVNTRYTKRYKQAKSSQSAIMVDAKGERIIINYPSPDLLPDAE
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCHH
WLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLDGDITPQDISELVALSDHAAF
HHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCC
SEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTT
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCEEEEEEECC
GAGDVFHGALAVVLATGGDLAESVRFASGVAASKCTRPGGRAGIPDCDQTRSFLSLFV
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGR
CEEEEEEHHHHHHHHHEEECCCCCCCCEEECCCHHCCCCHHHHHHHHHHHHCCCEEEEEC
VGDDDTGNSLLAELESWGVNTRYTKRYKQAKSSQSAIMVDAKGERIIINYPSPDLLPDAE
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCHH
WLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLDGDITPQDISELVALSDHAAF
HHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCC
SEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTT
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCEEEEEEECC
GAGDVFHGALAVVLATGGDLAESVRFASGVAASKCTRPGGRAGIPDCDQTRSFLSLFV
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]