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The map label for this gene is cdsA2 [H]

Identifier: 209396975

GI number: 209396975

Start: 1908649

End: 1909545

Strand: Direct

Name: cdsA2 [H]

Synonym: ECH74115_2012

Alternate gene names: 209396975

Gene position: 1908649-1909545 (Clockwise)

Preceding gene: 209395890

Following gene: 209397036

Centisome position: 34.25

GC content: 44.04

Gene sequence:

>897_bases
ATGCTGGAAAAATCTCTGGCAACACTTTTCGCGTTGTTAATTTTAGCAACGCTGATAAACCGTTTTCGGGTATGGCGGTT
ACCGGAGAGAAAAGGGGATGAAGTTACACTACGTATTCGTACCTGGTGGGGTATCGTCATTTGTTTTTCACTGGTGATTT
CAGGTCCACGCTGGATGACGTTGACGTTTTTTGCGCTGATAAGTTTTCTGGCATTGAAAGAATATTGTACGCTTATATCC
GTACATTTTCCGCGTTGGTTATATTGGGTTATTCCTCTTAACTATTTGCTTATCGGTTTTAGTTGCTTTGAGCTGTTTCT
GTTATTTATACCTTTGGCTGGGTTTCTGATATTAACCACCTGGCGAGTTTTAGTAGGTGATACCTCCGGTTTTCTGCATA
CCGTGAGCGCCATTTTTTGGGGCTGGATAATGACCGTTTTCGCCTTGAGTCATGCCGCCTGGTTATTAATGTTGACAACC
ACAAATACCCAGGGCGGGGCGTTACTGGTGTTATTTCTTTTGGCGTTAACAGAGTCAAACGATATTGCACAGTATTTATG
GGGGAAATCCTGCGGCAGAAGAAAAGTGGTCCCCAAAGTCAGCCCGGGAAAAACGCTGGAAGGTCTGGTGGGGGGCGTAA
TCACCACCATGATTGCGTCACTGATTATTGGACCGTTGCTGACACCGCTAAATACATTACAGGCATTATTAGCGGGTTTG
TTAATTGGTATTAGTGGTTTTTGCGGCGATGTAGTGATGTCAGCCGTCAAACGAGATGTGGGTGTTAAAGATAGCGGAAA
ACTATTACCAGGACATGGCGGACTCCTTGACAGGATTGACTCATTAATTTTCACCGCTCCGGTATTTTTTTATTTTATTC
GCTACTGCTGTTACTGA

Upstream 100 bases:

>100_bases
TGCAATGGAATAATCTTTTATGGAGCATTGCTTCAATTCTGCTTCTCTGGACTGCGATTAATCGTTGTCGGAGTGTGCTC
CTGATGAGTGCTGAAAGATA

Downstream 100 bases:

>100_bases
AGGAAAATAGAGAAAATGGAAAATTCACGCATCCCTGGGGAACATTTTTTTACCACCAGTGATAATACAGCGTTGTTTTA
TCGGCACTGGCCCGCTTTAC

Product: phosphatidate cytidylyltransferase

Products: diphosphate; CDPdiacylglycerol

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWGIVICFSLVISGPRWMTLTFFALISFLALKEYCTLIS
VHFPRWLYWVIPLNYLLIGFSCFELFLLFIPLAGFLILTTWRVLVGDTSGFLHTVSAIFWGWIMTVFALSHAAWLLMLTT
TNTQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMIASLIIGPLLTPLNTLQALLAGL
LIGISGFCGDVVMSAVKRDVGVKDSGKLLPGHGGLLDRIDSLIFTAPVFFYFIRYCCY

Sequences:

>Translated_298_residues
MLEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWGIVICFSLVISGPRWMTLTFFALISFLALKEYCTLIS
VHFPRWLYWVIPLNYLLIGFSCFELFLLFIPLAGFLILTTWRVLVGDTSGFLHTVSAIFWGWIMTVFALSHAAWLLMLTT
TNTQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMIASLIIGPLLTPLNTLQALLAGL
LIGISGFCGDVVMSAVKRDVGVKDSGKLLPGHGGLLDRIDSLIFTAPVFFYFIRYCCY
>Mature_298_residues
MLEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWGIVICFSLVISGPRWMTLTFFALISFLALKEYCTLIS
VHFPRWLYWVIPLNYLLIGFSCFELFLLFIPLAGFLILTTWRVLVGDTSGFLHTVSAIFWGWIMTVFALSHAAWLLMLTT
TNTQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMIASLIIGPLLTPLNTLQALLAGL
LIGISGFCGDVVMSAVKRDVGVKDSGKLLPGHGGLLDRIDSLIFTAPVFFYFIRYCCY

Specific function: Unknown

COG id: COG4589

COG function: function code R; Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI1787677, Length=298, Percent_Identity=94.6308724832215, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI87081696, Length=137, Percent_Identity=41.6058394160584, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: 2.7.7.41

Molecular weight: Translated: 33249; Mature: 33249

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWGIVICFSLVISGPRWMT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCHHH
LTFFALISFLALKEYCTLISVHFPRWLYWVIPLNYLLIGFSCFELFLLFIPLAGFLILTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRVLVGDTSGFLHTVSAIFWGWIMTVFALSHAAWLLMLTTTNTQGGALLVLFLLALTESN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCC
DIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMIASLIIGPLLTPLNTLQALLAGL
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGISGFCGDVVMSAVKRDVGVKDSGKLLPGHGGLLDRIDSLIFTAPVFFYFIRYCCY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWGIVICFSLVISGPRWMT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCHHH
LTFFALISFLALKEYCTLISVHFPRWLYWVIPLNYLLIGFSCFELFLLFIPLAGFLILTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRVLVGDTSGFLHTVSAIFWGWIMTVFALSHAAWLLMLTTTNTQGGALLVLFLLALTESN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCC
DIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMIASLIIGPLLTPLNTLQALLAGL
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGISGFCGDVVMSAVKRDVGVKDSGKLLPGHGGLLDRIDSLIFTAPVFFYFIRYCCY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; phosphatidate

Specific reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 9097039 [H]