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The map label for this gene is cfa [H]

Identifier: 209395995

GI number: 209395995

Start: 2247419

End: 2248567

Strand: Direct

Name: cfa [H]

Synonym: ECH74115_2374

Alternate gene names: 209395995

Gene position: 2247419-2248567 (Clockwise)

Preceding gene: 209400712

Following gene: 209397056

Centisome position: 40.33

GC content: 48.3

Gene sequence:

>1149_bases
ATGAGTTCATCGTGTATAGAAGAAGTCAGTGTACCGGATGACAACTGGTACCGTATCGCCAACGAATTACTTAGCCGTGC
CGGTATAGCCATTAACGGTTCTGCCCCGGCGGATATTCGTGTGAAAAACCCCGATTTTTTTAAACGCGTTCTGCAAGAAG
GCTCTTTGGGGTTAGGCGAAAGTTATATGGATGGCTGGTGGGAATGTGACCGACTGGATATGTTTTTTAGCAAAGTCTTA
CGCGCAGGTCTCGAGAACCAACTCCCCCATCATTTCAAAGACACGCTGCGTATTGCCGGCGCCCGTCTCTTCAATCTGCA
GAGTAAAAAACGTGCCTGGATAGTCGGCAAAGAGCATTACGATTTGGGTAATGACTTGTTCAGCCGCATGCTTGATCCCT
TCATGCAATATTCCTGCGCTTACTGGAAAGATGCCGATAATCTGGAATCTGCCCAGCAGGCGAAGCTCAAAATGATTTGT
GAAAAATTGCAGTTAAAACCTGGGATGCGCGTACTGGATATTGGCTGCGGCTGGGGCGGACTGGCACACTACATGGCATC
TAATTATGACGTAAGCGTGGTGGGCGTCACCATTTCTGCCGAACAGCAAAAAATGGCTCAGGAACGCTGTGAAGGCCTGG
ATGTCACCATTTTGCTGCAAGATTATCGTGACCTGAACGACCAGTTTGATCGTATTGTTTCTGTGGGGATGTTCGAGCAC
GTCGGACCGAAAAATTACGATACCTATTTTACGGTGGTGGATCGTAATTTGAAACCGGAAGGCATATTCCTGCTCCATAC
TATCGGTTCGAAAAAAACCGATCTGAATGTTGATCCCTGGATTAATAAATATATTTTCCCGAACGGTTGCCTGCCCTCTG
TACGCCAGATTGCTCAGTCCAGCGAACCCCACTTTGTGATGGAAGACTGGCATAACTTCGGTGCTGATTACGATACTACG
TTGATGGCGTGGTATGAACGATTCGTCGCCGCATGGCCAGAAATTGCGGATAACTACAGTGAACGCTTTAAACGGATGTT
TACCTATTATCTGAATGCCTGCGCAGGTGCTTTCCGCGCCCGTGATATTCAGCTCTGGCAGGTGGTGTTCTCACGCGGTG
TTGAAAACGGCCTTCGAGTCGCTCGCTAA

Upstream 100 bases:

>100_bases
GATTATAGACTCGCGGTTTTTTCTGCGAGATTTCTCACAAAGCCCAAAAAGCGTCTACGCTGTTTTAAGGTTCTGATCAC
CGACCAGTGATGGAGAAACT

Downstream 100 bases:

>100_bases
AGGCTATTCTATCGCCCCCTCTCCGGGGGCGATTTCAGATCAGGCTTCTGTACCTGATTGATTCATGGCATTTTCTCGTG
CCGCCAGCACACGTTCTACC

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVL
RAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEH
VGPKNYDTYFTVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTT
LMAWYERFVAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR

Sequences:

>Translated_382_residues
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVL
RAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEH
VGPKNYDTYFTVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTT
LMAWYERFVAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>Mature_381_residues
SSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLR
AGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICE
KLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHV
GPKNYDTYFTVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTL
MAWYERFVAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=382, Percent_Identity=99.4764397905759, Blast_Score=798, Evalue=0.0,
Organism=Caenorhabditis elegans, GI133904226, Length=385, Percent_Identity=30.9090909090909, Blast_Score=144, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 43925; Mature: 43794

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGE
CCCHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCCEEECCHHHHHHHHHCCCCCCCC
SYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHY
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHC
DLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
LAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEH
HHHHHHCCCCEEEEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
VGPKNYDTYFTVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQS
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHCC
SEPHFVMEDWHNFGADYDTTLMAWYERFVAAWPEIADNYSERFKRMFTYYLNACAGAFRA
CCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIQLWQVVFSRGVENGLRVAR
HHHHHHHHHHHHCHHCCCCCCC
>Mature Secondary Structure 
SSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGE
CCHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCCEEECCHHHHHHHHHCCCCCCCC
SYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHY
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHC
DLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
LAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEH
HHHHHHCCCCEEEEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
VGPKNYDTYFTVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQS
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHCC
SEPHFVMEDWHNFGADYDTTLMAWYERFVAAWPEIADNYSERFKRMFTYYLNACAGAFRA
CCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIQLWQVVFSRGVENGLRVAR
HHHHHHHHHHHHCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]