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The map label for this gene is DegQ3 [H]

Identifier: 20809027

GI number: 20809027

Start: 2577838

End: 2578941

Strand: Reverse

Name: DegQ3 [H]

Synonym: TTE2683

Alternate gene names: 20809027

Gene position: 2578941-2577838 (Counterclockwise)

Preceding gene: 20809028

Following gene: 20809026

Centisome position: 95.89

GC content: 40.49

Gene sequence:

>1104_bases
ATGCAGTATAATTTTAATAAGTTAGTTGCTACTGCAATAATTTCGTCCTTTATCACTTCTTTAATTTTTATATACATTGC
GCCTAATTTTTTATGGGGCAAAATTATTCCTATACCATATCCCCCTGAGTCGGGCTTAAAAAAAGAAATAGTGATTCCCG
AGAGAGAGCCTCCTACTGTAGCAGAAGCGGTGGCAAAAAAAGCGACACCGGCTGTAGTTGGCATAACAACGCTGGAATTT
GAGAGAAAGTATTATTTTTTAGAAAGGGCTGTTGAAGGAGTCGGTTCGGGATTTATAGTGCACCCCGACGGTTACATAAT
AACAAATAATCATGTGGTTAACGAAAATTCCAGAAATATAAAGGTTTATTTGAGCAATGGAAATATATTGCCGGGGAAAG
TAATGTGGACTGACCCGGTTTTAGACCTCACTATACTTAAGGTAGATGCGAAGAATCTGCCAGTGATTGAGCTGGGGGAC
TCTGATAGGCTTTCTGTAGGTCAAACGGCTATCGCTATAGGAAATCCTTTGGGGTTAAGATTTCAGAGAACGGTGACTTT
AGGAATAATAAGTGCACTCAACAGAAGCCTTCCCATAACTGAAGACAGTAAGCCCAAAATCATGGAAGACCTCATACAGA
CAGACGCTTCTATAAATCCGGGTAATAGCGGCGGACCTCTGATGGACTCTCAAGGGTACGCCATTGGGATAAATACTGCT
AAAGTCACTACTGCAGAGGGTTTAGGCTTTGCAATTCCTATAAACATTGTAAAGCCTATTCTTAAAAAGGTCATTGAAAC
AGGGACTTTCAAACCGCCTTACTTAGGAATAGTGGCGTATGACAGAGAGATTGCGAGTTACATAACTGCAGATGTGTATA
TTTACGAAGGGATATACGTGGCGGATATAGACCCTACAGGGCCCGCCTATAAAGCTGGAATAAGGAAAGGTTATATCATA
CTGGAGGTAGATGGGAAACCAGTAAATACGATGACAGGTCTAAAGTGCATCATATACGAAAAAAAGCCGGGAGAAAGCAT
AAAAGTTAAGTATAAGACGTTGACTGGGAAGGAAGGTTATGTTACTATTGTCCTTGGAAAGTAA

Upstream 100 bases:

>100_bases
TCAGGCTTTAGGAGCTGACATAATAAGAATAAGAGAATGAGAGTAAAAATTCGTGTATAATGAACTGCATAACATCTAAT
CCTATTAATGGGGTGATGTT

Downstream 100 bases:

>100_bases
AAAGCTTCTTGTAATCTTAAGGTCAAAGTTGGCGCTACCATGTTTTTTGGAACAGGAGAGAGTTTGATGTATGTAGTGTG
TGAAAAGCATTTAGAGGACG

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MQYNFNKLVATAIISSFITSLIFIYIAPNFLWGKIIPIPYPPESGLKKEIVIPEREPPTVAEAVAKKATPAVVGITTLEF
ERKYYFLERAVEGVGSGFIVHPDGYIITNNHVVNENSRNIKVYLSNGNILPGKVMWTDPVLDLTILKVDAKNLPVIELGD
SDRLSVGQTAIAIGNPLGLRFQRTVTLGIISALNRSLPITEDSKPKIMEDLIQTDASINPGNSGGPLMDSQGYAIGINTA
KVTTAEGLGFAIPINIVKPILKKVIETGTFKPPYLGIVAYDREIASYITADVYIYEGIYVADIDPTGPAYKAGIRKGYII
LEVDGKPVNTMTGLKCIIYEKKPGESIKVKYKTLTGKEGYVTIVLGK

Sequences:

>Translated_367_residues
MQYNFNKLVATAIISSFITSLIFIYIAPNFLWGKIIPIPYPPESGLKKEIVIPEREPPTVAEAVAKKATPAVVGITTLEF
ERKYYFLERAVEGVGSGFIVHPDGYIITNNHVVNENSRNIKVYLSNGNILPGKVMWTDPVLDLTILKVDAKNLPVIELGD
SDRLSVGQTAIAIGNPLGLRFQRTVTLGIISALNRSLPITEDSKPKIMEDLIQTDASINPGNSGGPLMDSQGYAIGINTA
KVTTAEGLGFAIPINIVKPILKKVIETGTFKPPYLGIVAYDREIASYITADVYIYEGIYVADIDPTGPAYKAGIRKGYII
LEVDGKPVNTMTGLKCIIYEKKPGESIKVKYKTLTGKEGYVTIVLGK
>Mature_367_residues
MQYNFNKLVATAIISSFITSLIFIYIAPNFLWGKIIPIPYPPESGLKKEIVIPEREPPTVAEAVAKKATPAVVGITTLEF
ERKYYFLERAVEGVGSGFIVHPDGYIITNNHVVNENSRNIKVYLSNGNILPGKVMWTDPVLDLTILKVDAKNLPVIELGD
SDRLSVGQTAIAIGNPLGLRFQRTVTLGIISALNRSLPITEDSKPKIMEDLIQTDASINPGNSGGPLMDSQGYAIGINTA
KVTTAEGLGFAIPINIVKPILKKVIETGTFKPPYLGIVAYDREIASYITADVYIYEGIYVADIDPTGPAYKAGIRKGYII
LEVDGKPVNTMTGLKCIIYEKKPGESIKVKYKTLTGKEGYVTIVLGK

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=281, Percent_Identity=37.3665480427046, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI22129776, Length=299, Percent_Identity=35.7859531772575, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI24308541, Length=282, Percent_Identity=34.7517730496454, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7019477, Length=311, Percent_Identity=33.4405144694534, Blast_Score=122, Evalue=4e-28,
Organism=Escherichia coli, GI1786356, Length=252, Percent_Identity=41.6666666666667, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789629, Length=265, Percent_Identity=38.8679245283019, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789630, Length=303, Percent_Identity=35.3135313531353, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646839, Length=293, Percent_Identity=32.7645051194539, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39992; Mature: 39992

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYNFNKLVATAIISSFITSLIFIYIAPNFLWGKIIPIPYPPESGLKKEIVIPEREPPTV
CCCCHHHHHHHHHHHHHHHHHHEEHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHH
AEAVAKKATPAVVGITTLEFERKYYFLERAVEGVGSGFIVHPDGYIITNNHVVNENSRNI
HHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCEEECCCCEEEECCEEECCCCCEE
KVYLSNGNILPGKVMWTDPVLDLTILKVDAKNLPVIELGDSDRLSVGQTAIAIGNPLGLR
EEEECCCCCCCCEEEEECCCEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCE
FQRTVTLGIISALNRSLPITEDSKPKIMEDLIQTDASINPGNSGGPLMDSQGYAIGINTA
EEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCE
KVTTAEGLGFAIPINIVKPILKKVIETGTFKPPYLGIVAYDREIASYITADVYIYEGIYV
EEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHEEEEEEECCEEE
ADIDPTGPAYKAGIRKGYIILEVDGKPVNTMTGLKCIIYEKKPGESIKVKYKTLTGKEGY
EECCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCE
VTIVLGK
EEEEECC
>Mature Secondary Structure
MQYNFNKLVATAIISSFITSLIFIYIAPNFLWGKIIPIPYPPESGLKKEIVIPEREPPTV
CCCCHHHHHHHHHHHHHHHHHHEEHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHH
AEAVAKKATPAVVGITTLEFERKYYFLERAVEGVGSGFIVHPDGYIITNNHVVNENSRNI
HHHHHHCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCEEECCCCEEEECCEEECCCCCEE
KVYLSNGNILPGKVMWTDPVLDLTILKVDAKNLPVIELGDSDRLSVGQTAIAIGNPLGLR
EEEECCCCCCCCEEEEECCCEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCE
FQRTVTLGIISALNRSLPITEDSKPKIMEDLIQTDASINPGNSGGPLMDSQGYAIGINTA
EEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCE
KVTTAEGLGFAIPINIVKPILKKVIETGTFKPPYLGIVAYDREIASYITADVYIYEGIYV
EEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHEEEEEEECCEEE
ADIDPTGPAYKAGIRKGYIILEVDGKPVNTMTGLKCIIYEKKPGESIKVKYKTLTGKEGY
EECCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCE
VTIVLGK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]