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The map label for this gene is rlmH1

Identifier: 20809024

GI number: 20809024

Start: 2576740

End: 2577141

Strand: Direct

Name: rlmH1

Synonym: TTE2680

Alternate gene names: 20809024

Gene position: 2576740-2577141 (Clockwise)

Preceding gene: 20809012

Following gene: 20809036

Centisome position: 95.81

GC content: 31.09

Gene sequence:

>402_bases
ATGAACTACAAGTTTTTTATCATAGCCAAAAAAATAGAACCCTTTTACCAAGAAGCCATAGAGGAATATTTTAAGAGATT
GCAGAGGTTTTGCAGCATTTCTCTTTCAATCTGTAAAAATTCAAAAAAACTTCCTGTAAAAGATTTGGAAAAATCTTATA
AAATATTGATTACACCTCAAGGGAAAACCATCTCTTCCGAAAAATTTGCTTTAAAGATAAAGGACCTAGAAATGAAATCC
ATAACAGATATAACTTTTTTAATAGGAGAAGGAATCGAGATTTTTGATGAAATATTTACAATTTCGCAAATGAAAATGTC
AAAGGGATTAATTGCTACGCTCCTCGCAGAACAGCTCTACCGCGCTTATAAAATATTGAGGAATGAACCATACCACAAAT
AA

Upstream 100 bases:

>100_bases
CCCCCATCAGTTGGTTTTTGTATTATTGTATCAAAGTGAAAAAATATTTTCAAATGTTTTTTTGATATAATAAGGATATA
ATGAAAAAGCAGGTGAAAAA

Downstream 100 bases:

>100_bases
ACTACAAAAGAGCATAATAAATTTGCTCTAAAAGCAAAAGCCTTGTGAGCTGATGAGGAAAAGTCATCTTAGAAAAAGAG
ATGTTTACATCAGCCCTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase 1; rRNA (pseudouridine-N3-)-methyltransferase rlmH 1

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MNYKFFIIAKKIEPFYQEAIEEYFKRLQRFCSISLSICKNSKKLPVKDLEKSYKILITPQGKTISSEKFALKIKDLEMKS
ITDITFLIGEGIEIFDEIFTISQMKMSKGLIATLLAEQLYRAYKILRNEPYHK

Sequences:

>Translated_133_residues
MNYKFFIIAKKIEPFYQEAIEEYFKRLQRFCSISLSICKNSKKLPVKDLEKSYKILITPQGKTISSEKFALKIKDLEMKS
ITDITFLIGEGIEIFDEIFTISQMKMSKGLIATLLAEQLYRAYKILRNEPYHK
>Mature_133_residues
MNYKFFIIAKKIEPFYQEAIEEYFKRLQRFCSISLSICKNSKKLPVKDLEKSYKILITPQGKTISSEKFALKIKDLEMKS
ITDITFLIGEGIEIFDEIFTISQMKMSKGLIATLLAEQLYRAYKILRNEPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH1_THETN (Q8R6V4)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_624195.1
- ProteinModelPortal:   Q8R6V4
- GeneID:   997740
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2680
- NMPDR:   fig|273068.3.peg.2216
- HOGENOM:   HBG622807
- OMA:   ISLSICK
- ProtClustDB:   CLSK901811
- BioCyc:   TTEN273068:TTE2680-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 15647; Mature: 15647

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKFFIIAKKIEPFYQEAIEEYFKRLQRFCSISLSICKNSKKLPVKDLEKSYKILITPQ
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCC
GKTISSEKFALKIKDLEMKSITDITFLIGEGIEIFDEIFTISQMKMSKGLIATLLAEQLY
CCEECCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYKILRNEPYHK
HHHHHHHCCCCCC
>Mature Secondary Structure
MNYKFFIIAKKIEPFYQEAIEEYFKRLQRFCSISLSICKNSKKLPVKDLEKSYKILITPQ
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCC
GKTISSEKFALKIKDLEMKSITDITFLIGEGIEIFDEIFTISQMKMSKGLIATLLAEQLY
CCEECCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYKILRNEPYHK
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336