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The map label for this gene is MhpC4 [C]

Identifier: 20808897

GI number: 20808897

Start: 2437551

End: 2438408

Strand: Reverse

Name: MhpC4 [C]

Synonym: TTE2547

Alternate gene names: 20808897

Gene position: 2438408-2437551 (Counterclockwise)

Preceding gene: 20808898

Following gene: 20808896

Centisome position: 90.67

GC content: 37.06

Gene sequence:

>858_bases
ATGTTTCCCGGCTTTTTATGTAGAAATTTTTTTAAAAAGAAATTAATGTGGTATTATAATTGGCGCACAAATGCTATAAT
ATATATTAGCAATTTTAGTACAGGAGTGAAAAAAGTGTACATCAATATAGACGGGATAAATATTTTCTACAAGAAAGAAG
GGCAGGGCAAAAAAGTTTTATTTCTGCACGGATGGGGAGGAAATTCGAATAGCTTTTTACCCGTATTTAATGCTTTGTCA
AAGGAATTCGAAGTGTACGCCGTAGATTTTCCGGGCTTTGGAAGGTCTGACTTTCCTGATGGAGATTGGGACGTCACAAG
GTATATGGAAATTACATATAAGTTTTTAGAAAGATTAGGGCTTGAAAAGGTCAGTATAATAGCCCATTCATTTGGCGGAC
GTGTTGCTATAATGCTGGCAGCTCTCCACCCAGAGGTGGTAGATAAACTTGTCTTGGTAAATAGTGCAGGTTTAATTCCC
AAAAGGGGATGGAAGTATTACTACAGAGTGTACAGGTTTAAGCTTATAAAAAGCCTGCTTTTGCTTTTGGGCAAAAAGGA
TGCGGTGGAAAAATTATACGAAAGATATGGTTCAAAGGACTACAAAGAGGCAGGCCGCTTAAGAGGTACTTTTGTTAAAG
TGATAAATCAGGACTTAAGGGGATATTTAAAAAAGATAAAGGCACCTACACTTCTCATATGGGGCGATAAGGACAGGGAA
ACTCCCATTGAATTTGCAAAGATTATGGAAAAAGAAATTCCCGATGCTGGATTGGTGGTTTTTGAAAATGCAGGACACTT
TTCTTATTTGGAGAGGCTAAATGATTTTATCATAATCGTAAGCTATTTCTTGAGGTGA

Upstream 100 bases:

>100_bases
ACTGCGGTAACTTAGTGAAACTTGCAATTCAGAGAGCAGAGAAGATGCTAGTTGAAAACTACAACAACGGAAAAGTCACC
CTCTAAACCCTCGGCCGGGA

Downstream 100 bases:

>100_bases
TAAGAGTGGCAAATTTGATTGGGATAGCTCTTGTAGTTTTATCTTTTATCTTGGTTGTGTTTTTCTACGGAAAGAAGGAG
CTTCATATGGCACAGCTGGA

Product: alpha/beta superfamily hydrolase/acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFPGFLCRNFFKKKLMWYYNWRTNAIIYISNFSTGVKKVYINIDGINIFYKKEGQGKKVLFLHGWGGNSNSFLPVFNALS
KEFEVYAVDFPGFGRSDFPDGDWDVTRYMEITYKFLERLGLEKVSIIAHSFGGRVAIMLAALHPEVVDKLVLVNSAGLIP
KRGWKYYYRVYRFKLIKSLLLLLGKKDAVEKLYERYGSKDYKEAGRLRGTFVKVINQDLRGYLKKIKAPTLLIWGDKDRE
TPIEFAKIMEKEIPDAGLVVFENAGHFSYLERLNDFIIIVSYFLR

Sequences:

>Translated_285_residues
MFPGFLCRNFFKKKLMWYYNWRTNAIIYISNFSTGVKKVYINIDGINIFYKKEGQGKKVLFLHGWGGNSNSFLPVFNALS
KEFEVYAVDFPGFGRSDFPDGDWDVTRYMEITYKFLERLGLEKVSIIAHSFGGRVAIMLAALHPEVVDKLVLVNSAGLIP
KRGWKYYYRVYRFKLIKSLLLLLGKKDAVEKLYERYGSKDYKEAGRLRGTFVKVINQDLRGYLKKIKAPTLLIWGDKDRE
TPIEFAKIMEKEIPDAGLVVFENAGHFSYLERLNDFIIIVSYFLR
>Mature_285_residues
MFPGFLCRNFFKKKLMWYYNWRTNAIIYISNFSTGVKKVYINIDGINIFYKKEGQGKKVLFLHGWGGNSNSFLPVFNALS
KEFEVYAVDFPGFGRSDFPDGDWDVTRYMEITYKFLERLGLEKVSIIAHSFGGRVAIMLAALHPEVVDKLVLVNSAGLIP
KRGWKYYYRVYRFKLIKSLLLLLGKKDAVEKLYERYGSKDYKEAGRLRGTFVKVINQDLRGYLKKIKAPTLLIWGDKDRE
TPIEFAKIMEKEIPDAGLVVFENAGHFSYLERLNDFIIIVSYFLR

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Escherichia coli, GI1789817, Length=250, Percent_Identity=25.6, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081721, Length=266, Percent_Identity=25.9398496240602, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 33196; Mature: 33196

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPGFLCRNFFKKKLMWYYNWRTNAIIYISNFSTGVKKVYINIDGINIFYKKEGQGKKVL
CCCHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCEEEEEEEEECEEEEEEECCCCCEEE
FLHGWGGNSNSFLPVFNALSKEFEVYAVDFPGFGRSDFPDGDWDVTRYMEITYKFLERLG
EEEECCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
LEKVSIIAHSFGGRVAIMLAALHPEVVDKLVLVNSAGLIPKRGWKYYYRVYRFKLIKSLL
CHHHHHHHHCCCCCEEEHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLLGKKDAVEKLYERYGSKDYKEAGRLRGTFVKVINQDLRGYLKKIKAPTLLIWGDKDRE
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
TPIEFAKIMEKEIPDAGLVVFENAGHFSYLERLNDFIIIVSYFLR
CHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFPGFLCRNFFKKKLMWYYNWRTNAIIYISNFSTGVKKVYINIDGINIFYKKEGQGKKVL
CCCHHHHHHHHHHHHEEEEEECCCEEEEEECCCCCEEEEEEEEECEEEEEEECCCCCEEE
FLHGWGGNSNSFLPVFNALSKEFEVYAVDFPGFGRSDFPDGDWDVTRYMEITYKFLERLG
EEEECCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
LEKVSIIAHSFGGRVAIMLAALHPEVVDKLVLVNSAGLIPKRGWKYYYRVYRFKLIKSLL
CHHHHHHHHCCCCCEEEHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLLGKKDAVEKLYERYGSKDYKEAGRLRGTFVKVINQDLRGYLKKIKAPTLLIWGDKDRE
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
TPIEFAKIMEKEIPDAGLVVFENAGHFSYLERLNDFIIIVSYFLR
CHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]