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The map label for this gene is cbiZ [H]

Identifier: 20808787

GI number: 20808787

Start: 2317227

End: 2317805

Strand: Reverse

Name: cbiZ [H]

Synonym: TTE2426

Alternate gene names: 20808787

Gene position: 2317805-2317227 (Counterclockwise)

Preceding gene: 20808791

Following gene: 20808785

Centisome position: 86.18

GC content: 35.75

Gene sequence:

>579_bases
ATGGAAACAATAATAAAGCCTGATATAGTGATAATAAAAGGGAATTTTTATGGCTTAAGTTCAGGAATCTTAGGAGGTTT
TGGAGAAGTAGATTTTGTATTTAATCATACAATTCCTGAGAAGGTGCTGGACGAATTTGATAAATTGAATCCAAAAGAGT
ATGTCAAAAAAGTTGCGCAAGATAATGGGATAGAAGGAAAGTACTTTGGACTTATAACGGCTGTCTCTATGGAAAGATTG
AGAGTTGTTAAGAGAAATGAAGTTACAGCATTTATAACTGCTGGTATTAAAAACCATAACCAGAAAATAAACGCAGGAAC
CATCAATATTATACTACACTTAGAAGCGAATTTGCAAGACAGTGCCCTTATAAATGCTATAATCACAGCTACAGAGGCAA
AGAGTATGGCGCTTCTCGAATTAGGGTATGACTTTACTGGGACAAGCACTGATGCAGTGGTAGTAGTTAGGGATAGAAAT
TGCAGTAAATTTTATGAATACGCAGGTCCAGAGAGTACTCTTGGCAAGTTCATATGGGAAGCGGTAAAAGAAGGAGTGAA
AAGAAGTCTAAAAGATTAA

Upstream 100 bases:

>100_bases
GAAAGCCCCATAGCCTACAGCAGCTACTTTGACCATATGTATCCCTCCAATTCAAAATGATATAATTATCTTTAGAAATT
AAACTTGGTGAGGGATGTAA

Downstream 100 bases:

>100_bases
AAGCGGGGGAACCCCGCTTAAAATTTTGAGGAAAAGGCTAGGTGGAATTTTTTCAGTATTATTTCAGTAAAAAGGCATAG
AGAGGAACTTGAATAGCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: AdoCbi hydrolase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
METIIKPDIVIIKGNFYGLSSGILGGFGEVDFVFNHTIPEKVLDEFDKLNPKEYVKKVAQDNGIEGKYFGLITAVSMERL
RVVKRNEVTAFITAGIKNHNQKINAGTINIILHLEANLQDSALINAIITATEAKSMALLELGYDFTGTSTDAVVVVRDRN
CSKFYEYAGPESTLGKFIWEAVKEGVKRSLKD

Sequences:

>Translated_192_residues
METIIKPDIVIIKGNFYGLSSGILGGFGEVDFVFNHTIPEKVLDEFDKLNPKEYVKKVAQDNGIEGKYFGLITAVSMERL
RVVKRNEVTAFITAGIKNHNQKINAGTINIILHLEANLQDSALINAIITATEAKSMALLELGYDFTGTSTDAVVVVRDRN
CSKFYEYAGPESTLGKFIWEAVKEGVKRSLKD
>Mature_192_residues
METIIKPDIVIIKGNFYGLSSGILGGFGEVDFVFNHTIPEKVLDEFDKLNPKEYVKKVAQDNGIEGKYFGLITAVSMERL
RVVKRNEVTAFITAGIKNHNQKINAGTINIILHLEANLQDSALINAIITATEAKSMALLELGYDFTGTSTDAVVVVRDRN
CSKFYEYAGPESTLGKFIWEAVKEGVKRSLKD

Specific function: Converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route [H]

COG id: COG1865

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiZ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002808 [H]

Pfam domain/function: PF01955 CbiZ [H]

EC number: =3.5.1.90 [H]

Molecular weight: Translated: 21248; Mature: 21248

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIIKPDIVIIKGNFYGLSSGILGGFGEVDFVFNHTIPEKVLDEFDKLNPKEYVKKVAQ
CCCCCCCCEEEEECCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHH
DNGIEGKYFGLITAVSMERLRVVKRNEVTAFITAGIKNHNQKINAGTINIILHLEANLQD
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEECCCEEEEEEEEECCCCH
SALINAIITATEAKSMALLELGYDFTGTSTDAVVVVRDRNCSKFYEYAGPESTLGKFIWE
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHHH
AVKEGVKRSLKD
HHHHHHHHHCCC
>Mature Secondary Structure
METIIKPDIVIIKGNFYGLSSGILGGFGEVDFVFNHTIPEKVLDEFDKLNPKEYVKKVAQ
CCCCCCCCEEEEECCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHH
DNGIEGKYFGLITAVSMERLRVVKRNEVTAFITAGIKNHNQKINAGTINIILHLEANLQD
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEECCCEEEEEEEEECCCCH
SALINAIITATEAKSMALLELGYDFTGTSTDAVVVVRDRNCSKFYEYAGPESTLGKFIWE
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHHH
AVKEGVKRSLKD
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]