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The map label for this gene is NanE

Identifier: 20808781

GI number: 20808781

Start: 2312373

End: 2312996

Strand: Reverse

Name: NanE

Synonym: TTE2420

Alternate gene names: 20808781

Gene position: 2312996-2312373 (Counterclockwise)

Preceding gene: 20808782

Following gene: 20808780

Centisome position: 86.0

GC content: 38.62

Gene sequence:

>624_bases
ATGGCGAAGATGGCTAAAGCTGCGGAGATTGGAGGGGCAGTAGCAATTAGAGCAAATGGTTATGAGGATATTGTTGCAAT
AAAGAAAGAGGTAAGTATTCCAGTAATAGGGCTTATAAAGAAAAGATACGAAGGATATGCCCCTTATATAACTCCAACAA
TGGAAGAAGTGGATAAAGTTATAGAAGCAGGAGCAGATATTGTTGCAATTGATGCTACTAAAGCTTATAAGCCGGGTGGT
TTAACAACGGGAGAGTTTTTAAAAAGGATAAAGGAGAAATATCCAAAAATATTGGTTATGGCAGATATTTCAACATACGA
GGAAGGTATAGAGGCGGAAAAGCTGGGTTTTGATCTAATCTCCACTACATTATCAGGTTATACAGAATATAGTCCGGAAT
TGGAAGGCCCAGATTATGAGTTAATAGAAAGATTGGCGAGAAAGGTAAATGTCCCAATAATAGCAGAAGGTAGAATATGG
ACTCCGGAGGAAGCTGTAAAAGCCTTAGAAAAAGGAGCGTATGCAGTTGTTGTAGGTACTGCTATTACCCGTCCTCATGA
GATCACAAGAAGGTTTGTGACTTTCATTAAGGAGAGGAGATATTCAAATGTCAGAGCAAAATAA

Upstream 100 bases:

>100_bases
ACAAAGAGGGATGCAGATGGATATAATACAAAAATTAGAAAACGGCTTAATAGTCTCATGTCAAGCTTTAGAAGGTGAAC
CTCTCCATAGTCCATTTATC

Downstream 100 bases:

>100_bases
TGGCAATGTAATATTAAAAATACAAAGTATATATAACTCTCTCACAAATGCGGAGAAAAAAGTGGCAGATTATGTGCTGG
AAAATGCTGAAAGCGTTATA

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MAKMAKAAEIGGAVAIRANGYEDIVAIKKEVSIPVIGLIKKRYEGYAPYITPTMEEVDKVIEAGADIVAIDATKAYKPGG
LTTGEFLKRIKEKYPKILVMADISTYEEGIEAEKLGFDLISTTLSGYTEYSPELEGPDYELIERLARKVNVPIIAEGRIW
TPEEAVKALEKGAYAVVVGTAITRPHEITRRFVTFIKERRYSNVRAK

Sequences:

>Translated_207_residues
MAKMAKAAEIGGAVAIRANGYEDIVAIKKEVSIPVIGLIKKRYEGYAPYITPTMEEVDKVIEAGADIVAIDATKAYKPGG
LTTGEFLKRIKEKYPKILVMADISTYEEGIEAEKLGFDLISTTLSGYTEYSPELEGPDYELIERLARKVNVPIIAEGRIW
TPEEAVKALEKGAYAVVVGTAITRPHEITRRFVTFIKERRYSNVRAK
>Mature_206_residues
AKMAKAAEIGGAVAIRANGYEDIVAIKKEVSIPVIGLIKKRYEGYAPYITPTMEEVDKVIEAGADIVAIDATKAYKPGGL
TTGEFLKRIKEKYPKILVMADISTYEEGIEAEKLGFDLISTTLSGYTEYSPELEGPDYELIERLARKVNVPIIAEGRIWT
PEEAVKALEKGAYAVVVGTAITRPHEITRRFVTFIKERRYSNVRAK

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=188, Percent_Identity=43.0851063829787, Blast_Score=131, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_THETN (Q8R7I7)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623952.1
- ProteinModelPortal:   Q8R7I7
- SMR:   Q8R7I7
- GeneID:   996750
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2420
- NMPDR:   fig|273068.3.peg.1824
- HOGENOM:   HBG296941
- OMA:   EHIVSWF
- ProtClustDB:   PRK01130
- BioCyc:   TTEN273068:TTE2420-MONOMER
- BRENDA:   5.1.3.9
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 22931; Mature: 22800

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKMAKAAEIGGAVAIRANGYEDIVAIKKEVSIPVIGLIKKRYEGYAPYITPTMEEVDKV
CCCHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
IEAGADIVAIDATKAYKPGGLTTGEFLKRIKEKYPKILVMADISTYEEGIEAEKLGFDLI
HHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHCCCHHHHHHHHH
STTLSGYTEYSPELEGPDYELIERLARKVNVPIIAEGRIWTPEEAVKALEKGAYAVVVGT
HHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCEECHHHHHHHHHCCCEEEEEEC
AITRPHEITRRFVTFIKERRYSNVRAK
HHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKMAKAAEIGGAVAIRANGYEDIVAIKKEVSIPVIGLIKKRYEGYAPYITPTMEEVDKV
CCHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
IEAGADIVAIDATKAYKPGGLTTGEFLKRIKEKYPKILVMADISTYEEGIEAEKLGFDLI
HHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHCCCHHHHHHHHH
STTLSGYTEYSPELEGPDYELIERLARKVNVPIIAEGRIWTPEEAVKALEKGAYAVVVGT
HHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCEECHHHHHHHHHCCCEEEEEEC
AITRPHEITRRFVTFIKERRYSNVRAK
HHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336